An immunochemical approach to model and long-term suppression of depressive and anxiety behavior

The inhibitor of monoaminooxydase isatin and the ligand of B-receptors cholecystokinin-4 play a significant role in the suppression and induction of depressive and anxiety states. We induced the formation of auto-antibodies to these compounds against their conjugates with antigen-carrier by immunization of white rats. The result was long-term (more than 2 months) stimulation of depressive and anxiety behavior after immunization to isatin and, in contrast, the suppression of such behavior after immunization to cholecystokinin. The perspective of immunochemical approach to long-term correction of behavior is discussed.     

Autobiographical memories for places

The purpose of the present exploratory study was to investigate operations and contents of a naturally occurring reminiscence for physical places in 26 Swedish participants. Using Conway and Pleydell-Pearce's (2000) model of autobiographical memory as a framework, two main questions were examined. First, in what sense are physical places ingredients of our selves-that is, of our self-knowledge-and, if so, how are they and their characteristics organised in the autobiographical knowledge base? Second, what form do personal memories for places take and what kinds of meanings and emotional contents do we bind to this type of reminiscence? The results showed that the Swedish participants' most important places in their lives were mainly childhood- and cottage-related rural types of milieus, and mostly categorised as summarised events; that is, frequently revisited. The personal recollections of the place-related event-specific knowledge were mostly of the generic imagery type, comprising semantic, perceptual, and emotional contents related to the "self", "others", and the "environment". The memories mainly reflected on the participants' growth period and feelings of activation and pleasantness. This was more pronounced in older (M = 59) than in younger (M = 35) participants. All this indicates that physical places can serve as thematic pathways guiding reminiscence and self-knowing consciousness as we recollect details of perceptual, semantic, and emotional characters of periods in our lives.     

Mapping Creativity: Creativity Measurements Network Analysis

This article borrowed network analysis tools to discover how the construct formed by the set of all measures of creativity configures itself. To this end, using a variant of the meta-analytical method, a database was compiled simulating 42,381 responses to 974 variables centered on 64 creativity measures. Results, although preliminary, indicate the existence of a core dimension filled with variables that indicate novelty, which is surrounded by the paired dimensions of negative affect and social leadership, and high cognitive performance and positive affect. As for the measurement instruments, it was found that, although tests of divergent thinking, self-reported biographies, and composite scores are the most appropriate tools to gauge creativity itself, both attitude and personality inventories are best for diagnosing the different kinds of creators.     

Qualia Compression

Color qualia inversion scenarios have played a key role in various philosophical debates. Most notably perhaps, they have figured in skeptical arguments for the fundamental unknowability of other persons’ color experiences. For these arguments to succeed, it must be assumed that a person's having inverted color qualia may go forever unnoticed. This assumption is now generally deemed to be implausible. The present paper defines a variant of color qualia inversion—termed ‘‘color qualia compression’’—and argues that the possibility of undetectable color qualia compression is immune to the objections that have been levelled against color qualia inversion arguments, and that color qualia compression scenarios support full‐blown skepticism regarding other people's color experiences.     

The Probabilities of Conditionals Revisited

According to what is now commonly referred to as “the Equation” in the literature on indicative conditionals, the probability of any indicative conditional equals the probability of its consequent of the conditional given the antecedent of the conditional. Philosophers widely agree in their assessment that the triviality arguments of Lewis and others have conclusively shown the Equation to be tenable only at the expense of the view that indicative conditionals express propositions. This study challenges the correctness of that assessment by presenting data that cast doubt on an assumption underlying all triviality arguments.     

Visual image retention does not contribute to modulation of event-related potentials by mental rotation

Rotation of a visual image in mind is associated with a slow posterior negative deflection of the event-related potential (ERP), termed rotation-related negativity (RRN). Retention of a visual image in short-term memory is also associated with a slow posterior negative ERP, termed negative slow wave (NSW). We tested whether short-term memory retention, indexed by the NSW, contributes to the RRN. ERPs were recorded in the same subjects in two tasks, a mental rotation task, eliciting the RRN, and a visual short-term memory task, eliciting the NSW. Over both right and left parietal scalp, no association was found between the NSW and the RRN amplitudes. Furthermore, adjusting for the effect of the NSW had no influence on a significant association between the RRN amplitude and response time, an index of mental rotation performance. Our data indicate that the RRN reflects manipulation of a visual image but not its retention in short-term memory.     

Simultaneous attentional guidance by working-memory and selection history reveals two distinct sources of attention

Recent theories of attention have proposed that selection history is a separate, dissociable source of information that influences attention. The current study sought to investigate the simultaneous involvement of selection history and working-memory on attention during visual search. Experiments 1 and 2 used target feature probability to manipulate selection history and found significant effects of both working-memory and selection history, although working-memory dominated selection history when they cued different locations. Experiment 3 eliminated the contribution of voluntary refreshing of working-memory and replicated the main effects, although selection history became dominant. Using the same methodology, but with reduced probability cue validity, both effects were present in Experiment 4 and did not significantly differ in their contribution to attention. Effects of selection history and working-memory never interacted. These results suggest that selection history and working-memory are separate influences on attention and have little impact on each other. Theoretical implications for models of attention are discussed.     

Lewis on fallible knowledge

Lewis has offered a contextualist epistemology that he claims is non-fallibilist. The present note aims to show that, while there seems to be a simple argument for Lewis's claim, the argument is fallacious, and Lewis's epistemology is fallibilist after all.     

The Educational Community as In-tentional Community

This paper reassesses a perennial concern of philosophy of education: the nature of the educational community and the role of the teacher in relation to such a community. As an entry point into this broader question, we turn to Philosophy for children (P4C), which has consistently emphasized the importance of community. Yet, not unlike pragmatist notions of community more broadly, the P4C community has largely focused on the goal-directed, purposive, aspect of the process of inquiry. The purpose of our paper is to move beyond P4C (as it has traditionally been conceived) in order to theorize a non-instrumental, in-tentional, educational community without pre-conceived goals or intentions. Drawing largely from the work of Italian philosopher Giorgio Agamben, we describe the P4C-classroom as one that refuses to be operative (moving forward toward reaching common goals) and thus undermines the taken-for-granted logic of means and ends that underlies how educational communities are typically depicted and justified. Again drawing from Agamben, we identify the specific ways in which the experience of love and friendship (both of which are pure means rather than means to an end) constitute the in-tentional community. The silence of the voice of the teacher enables the experience of love and friendship to come about. Being included as an exclusion via his/her silence, the teacher is neither immanent (facilitator of student learning) nor transcendent (outside or beyond learning) but alongside the community as a paradigm of friendship.     

Colorism and educational outcomes of Asian Americans: evidence from the National Longitudinal Study of Adolescent Health

Using a nationally representative longitudinal data set, the current study examines the link between colorism and educational attainment of Asian American young adults. Three levels of educational attainment are used as outcomes: high school diploma, some college and a Bachelor’s degree or higher. Independent variables include skin tone, ethnic origin, parental income and education, family structure, parental involvement, family social support and others. Given the fact that colorism affects genders disparately, the analyses are conducted separately for males and females. The findings suggest that, compared to their co-ethnics with light brown skin tone, Asian American males and females with white skin are more likely to be college educated. Conversely, the odds of getting a Bachelor’s degree or higher are significantly higher for Asian Americans with light skin tone than for their co-ethnics with dark brown skin tone. All in all, the findings point to the pattern of the inverse relationship between educational attainment and the darkness of skin tone.