Hippocampal synaptic plasticity during instrumental learning

present research examined the role of hippocampal NMDA-dependent synaptic potentiation on appetitive instrumental conditioning under a continuous reinforcement schedule. In the first experiment, low (.025 mg.kg) or moderate (.05 mg/kg) dosages of the NMDA receptor antagonist, MK801, failed to increase the number of training days required to reach acquisition criterion; number of training days required to reach criterion for extinction were also unaffected. In the second experiment, a higher dosage (.10 mg/kg) of MK801 or induction of long-term potentiation failed to alter the number of responses occurring during acquisition. These data suggest that hippocampal synaptic potentiation does not play a prominent role in instrumental learning with simple contingency conditions. It is suggested that hippocampal LTP reflects a perceptual process that contributes differentially to spatial cognition, classical and instrumental conditioning.     

Adaptiveness: A moderator of the adverse impact of hassles?

Adaptiveness constitutes coping consistently with Stressors so to reduce distress or, at worst, not aggravate it. Accordingly, it should moderate the adverse impact of hassles. Undergraduate volunteers (N = 200) responded to measures of hassles, adaptiveness, and the criteria of subjective distress, psychiatric symptomatology and minor physical ailments. In all three regression analyses, hassles made a substantial positive contribution and adaptiveness a small negative contribution to adverse outcome. The interaction between hassles and adaptiveness was non-significant in all three cases. Alternative interpretations were identified to guide further research.     

Hippocampal synaptic plasticity during instrumental learning

present research examined the role of hippocampal NMDA-dependent synaptic potentiation on appetitive instrumental conditioning under a continuous reinforcement schedule. In the first experiment, low (.025 mg.kg) or moderate (.05 mg/kg) dosages of the NMDA receptor antagonist, MK801, failed to increase the number of training days required to reach acquisition criterion; number of training days required to reach criterion for extinction were also unaffected. In the second experiment, a higher dosage (.10 mg/kg) of MK801 or induction of long-term potentiation failed to alter the number of responses occurring during acquisition. These data suggest that hippocampal synaptic potentiation does not play a prominent role in instrumental learning with simple contingency conditions. It is suggested that hippocampal LTP reflects a perceptual process that contributes differentially to spatial cognition, classical and instrumental conditioning.     

THE CREDIBLE SHRINKING ROOM:

Abstract— Becoming a proficient symbol user is a universal developmental last in the first years of life, but delecting and mentally representing symbolic relations can be quite challenging for young children To test the extent to which symbolic reasoning per se is problematic, we compared the performance of 2-year-olds in symbolic and nonsymbolic versions of a search task. The children had to use their knowledge of the location of a toy hidden in a room to draw an inference about where to find a miniature toy in a scale model of the room (and vice versa) Children in the nonsymbolic condition believed a shrinking machine had caused the room to become the model They were much more successful than children in the symbolic condition, for whom the model served as a symbol of the room The symbol understanding and use.     

TIME COURSE OF ACTIVATING BRAIN AREAS IN GENERATING VERBAL ASSOCIATIONS

Abstract— Generating a use far a visual word in comparison with reading the word aloud activates frontal attention areas first (170 MS), a left lateral frontal area next (250 ms), and then a left temporoparietal (Wernicke's) area (650 ms). A brief period of practice reduces these activations. If subjects are asked to respond to a word from the same practiced list by giving a novel use, the original activations reappear and are joined by activity similar in location and time to Wernicke's activation but in the right hemisphere. These findings demonstrate the time course of activations of neuroanatomical areas in word processing and indicate a role for the right hemisphere when semantic processing is more difficult, such as in generating a less frequent association in the presence of a highly practiced one.     

Family Functioning and Mental Illness: A Comparison of Psychiatric and Nonclinical Families

The primary objective of the present investigation was to examine adaptive functioning in the families of patients with a wide range of psychiatric disorders. Seven dimensions of family functioning, as measured by the Family Assessment Device (FAD), were compared across families of patients with a schizophrenia spectrum disorder (n = 61 ), bipolar disorder (n = 60 ), major depression (n = 111 ), anxiety disorder (n = 15 ), eating disorder (n = 26 ), substance abuse disorder (n = 48 ), and adjustment disorder (n = 46 ). Families in each psychiatric group were also compared to a control group of nonclinical families (N = 353 ). Results indicated that regardless of specific diagnosis, having a family member in an acute phase of a psychiatric illness was a risk factor for poor family functioning compared to the functioning of control families. However, with few exceptions, the type of the patient's psychiatric illness did not predict significant differences in family functioning. Thus, having a family member with a psychiatric illness is a general stressor for families, and family interventions should be considered for most patients who require a psychiatric hospitalization for either the onset of, or an acute exacerbation of, any psychiatric disorder.     

A Whiff of Reality: Empirical Evidence Concerning the Effects of Pleasant Fragrances on Work-Related Behavior1

Two studies were conducted to investigate the potential effects on workrelated behavior of one environmental variable: pleasant fragrances. In Study 1, participants performed a word construction task under low or high stress while in the presence or absence of pleasant fragrances. Performance was significantly enhanced by fragrance in both stress conditions. In addition, exposure to pleasant fragrances significantly increased performance on an additional task (decoding written messages) completed by participants following exposure to stress. In Study 2, both exposure to pleasant fragrances and receipt of a small gift increased performance on the same word construction task used in Study 1. In addition, fragrance and a gift increased participants' willingness to engage in both immediate and delayed helping. Together, the results of these studies offer support for the view that pleasant fragrances can influence work-related behavior, and that such effects may be mediated, at least in part, by increments in positive affect.     

Decision-making incapacity among nursing home residents: results from the 1987 NMES survey. National Medical Expenditure Survey

Recent legislative and regulatory developments have focused attention on older adults' capacity for involvement in health care decision-making. The Omnibus Budget Reconciliation Act of 1987 (OBRA 87) focused attention on the rights of nursing home residents to be involved in health care decision-making to the fullest extent possible. This article uses data from the 1987 National Medical Expenditure Survey (NMES) to examine rates of incapacity for health care decision-making among nursing home residents. Elements of the Oklahoma statute were used to operationalize decision-making incapacity: disability or disorder, difficulty in decision-making or communicating decisions, and functional disability. Fifty-three percent of nursing home residents had a combination of either physical or mental impairment and an impairment in either self-care or money management. The discussion focuses on the policy and practice implications of significant rates of incapacity among nursing home residents.     

Are All Hostility Scales Alike? Factor Structure and Covariation Among Measures of Hostility1

Few studies have examined the correlational and structural relationships between measures of hostility that may predict coronary heart disease. Using data from a population-based study (N= 2,682), we examined the factor structure among the five subscales from Siegel's (1986) Multi-dimensional Anger Inventory, the three subscales from Spielberger et al.'s (1985) anger expression scales, a Cook-Medley (Cook & Madley, 1954) hostility subscale that measures cynicism, and items measuring hostility from four scales that assess Type A behavior. Eight separate factors were identified: hostile anger expression, perceived control over the expression of one's anger, frequency of anger, ease of anger provocation, brooding, hostile outlook, cynicism, and sullenness. These results suggest that the structure of hostility measures is more complex than previous factor analyses have suggested. Our findings point to the dangers in assuming that a factor structure can be generalized beyond the data on which it is based to provide theoretical statements about psychological structure. The new scales appear to be valid because they correlate with demographic variables and indicators of social support in the expected directions.     

Behavioral Intentions: Which Ones Predict Fertility Behavior in Married Couples?1

The published literature on the relationship between behavioral intentions and fertility behavior exhibits four major problems: inconsistent and confusing use of theoretical constructs, limited use of different types of intentions, use of nonbehavioral outcomes, and failure to explore adequately the couple aspects of the intentions/behavior relationship. The study reported here addresses these problems by using a theoretical framework that characterizes the psychological/behavioral sequence leading to a planned conception, three different types of fertility intentions, a behavioral outcome variable, and data from 196 married couples with no children and 185 married couples with one child. Data analysis results in a simultaneous equation, constrained regression model which indicates that child-timing intentions are the most important predictors of proceptive behavior over a 3-1/2 year period and that childbearing intentions are next in importance; that behavioral intentions are the final common pathway through which fertility motivations, attitudes, beliefs, and desires affect behavior; that the use of proceptive behavior as an outcome variable improves the explanatory power of our models; and that the interaction of couple intentions do not demonstrate greater husband or wife influence over couple proceptive behavior but do demonstrate that disagreement has a delaying effect on the onset of that behavior.