Invited Address at the Occasion of the Bertelson Award 2005 Impairments in visual discrimination in amnesia: Implications for theories of the role of medial temporal lobe regions in human memory

A prominent and long-standing view of human long-term memory is that structures within the medial temporal lobe (MTL) work together to support the acquisition of memory for facts and events. In contrast to this view, recent studies in rats and non-human primates suggest dissociations in function between regions comprising the MTL. Evidence in support of such specialisation in humans, however, has been inconclusive, leading some researchers to propose that human MTL functions as a unitary system uniquely specialised for the acquisition and storage of long-term memory. This paper reviews some of the key studies from the animal and human literature that support an account of functional differentiation and discusses the different theoretical positions that have emerged from their findings. A series of recent experiments in humans designed to determine whether there is functional homogeneity in MTL regions across species are also reviewed and an alternative account of human memory—in which long-term memory is dependent upon representations distributed throughout the human brain rather than one specialised system—is proposed.     

Chronic psychological stress and the regulation of pro-inflammatory cytokines: a glucocorticoid-resistance model.

This study examined whether chronic stress impairs the immune system's capacity to respond to hormonal signals that terminate inflammation. Fifty healthy adults were studied; half were parents of cancer patients, and half were parents of healthy children. Parents of cancer patients reported more psychological distress than parents of healthy children. They also had flatter diurnal slopes of cortisol secretion, primarily because of reduced output during the morning hours. There was also evidence that chronic stress impaired the immune system's response to anti-inflammatory signals: The capacity of a synthetic glucocorticoid hormone to suppress in vitro production of the pro-inflammatory cytokine interleukin-6 was diminished among parents of cancer patients. Findings suggest a novel pathway by which chronic stress might alter the course of inflammatory disease.     

The effect of repeated experience on children's suggestibility across two question types

There is a discrepancy in the literature regarding the effect of repeated experience on children's suggestibility. Some researchers have concluded that repeated experience increases children's suggestibility for variable details whereas others have reported no detrimental effect. This study demonstrated that the type of question used to test memory (cued‐recall versus yes/no questions) could account for the different reported conclusions. Children aged 5–6 years took part in an event either once or four times. Three or 21 days later, they were given a suggestive interview about the single/final occurrence of the event during which half of the event details were inaccurately described. When later asked yes/no questions, the children with repeated experience agreed with more of the suggestions than did those in the single‐experience condition, especially at the longer delay. In relation to cued‐recall questions, however, experience did not mediate the number of times that false suggestions from the biasing interview were reported. This latter finding was revealed irrespective of the retention interval. Copyright © 2002 John Wiley & Sons, Ltd.     

Treatment Adherence in Children with Sickle Cell Disease: Disease-Related Risk and Psychosocial Resistance Factors

To identify disease-related risk factors and psychosocial resistance factors that impact adherence to prescribed treatment in the context of admission to a Hematology Acute Care Unit (HACU) designed to provide acute care for children with sickle cell disease (SCD) presenting with pain or fever. A total of 73 primary caregivers and 24 children (if age 8 or older) completed standardized forms during the HACU admission. Treatment adherence variables (medical staff rating, SCD-related care activities, percentage of agreement between treatment recommendations made and care activities, and attendance at hematology clinic) indicated moderate-to-high adherence. Based on regression analyses, the risk variable of disease-related stress and the resistance variables of family flexibility and less reliance on passive coping accounted for significant portions of the variance in treatment adherence. Empirical evaluation of interventions designed to improve communication regarding expectations for the care of children with SCD and to support active family problem solving during times of SCD-related stress must be ongoing.     

Influence of self-construals on the perception of different self-presentation styles in Korea

The present study investigated how perceivers' self-construals influence the perception of others who use self-enhancement or self-effacement in communication. It was predicated that independent self and interdependent self would differently affect the evaluation of self-enhancing presentation and self-effacing presentation. Two hundred and forty-six Korean college students read a scenario depicting a person using bragging, and positive and negative self-presentations for his/her accomplishment, and then evaluated the presenter in the scenario on intention of future interaction, satisfaction with conversation and likeability. Results showed that people with independent self evaluated the positive presentation more favorably than people with interdependent self, whereas people with interdependent self evaluated the negative presentation more favorably than people with independent self. No significant difference was found in the evaluation of bragging presentation. The results imply that although the purpose of self-presentation is to give positive self to others, it is differently expressed through self-enhancement in North American culture and through self-effacement in East Asian culture. The results also supported previous cross-cultural studies on self-enhancement and self-effacement by providing an examination from individual level analysis.     

汉语语句重音的分类和分布

通过两个独立进行的重音标注实验对汉语语句重音的分类和分布进行了初步探讨。实验l是由60位普通被试参加的音节重音突显度的知觉实验。实验2是由本文三位作者参加的重音类别标注实验,在此实验中语句重音被划分为节奏重音和语义重音。实验2中对于语句重音的分类性标注结果得到了实验l中普通被试对音节重音突显度知觉结果的支持,这说明人们确实能够感知到两种不同类型的重音。实验结果还表明,节奏重音倾向于出现在较大韵律单元内的最末韵律词的末音节上,并且与适当的停延相伴生,语义重音的分布则与语句的韵律结构的关系不大。     

Chisholm's Legacy on Intentionality

Abstract: The problem of intentionality, or how mind and language can take things in the world as “intentional objects,” engaged Chisholm throughout his philosophical career. This essay reviews and discusses his seminal contributions on this problem, from his early work in “Sentences about Believing” and Perceiving during the 1950s to his last and most mature account in The First Person, published in 1981 . Chisholm's final view was that de se reference, or a subject's directly taking himself as an intentional object, is fundamental and primitive, and that all other forms of intentional reference, such as de re and de dicto, can be understood on the basis of de se intentionality. The essay ends with a discussion of the worry that this account might lead to what may be called “intentional solipsism,” the proposition that the self is the only genuine object of intentional reference.     

Preparing Rural Adolescents for Post‐High School Transitions

In this study, the authors evaluated the impact of 4 career development curricular strategies and emotional/instrumental support in preparing rural adolescents to make successful post‐high school transitions. Curriculum strategies and perceived support helped 8th‐, 10th‐, and 12th‐grade students attain critical aspects of career development, enhanced student satisfaction that their education was better preparing them to achieve future educational and career goals, and increased student intentions to enter post‐high school settings that required greater levels of education and training. Girls reported earning higher grades and participating in more work‐based learning activities and intended to enter post–high school training settings that required more education than did boys.     

Cognitive development of lead exposed children from ages 6 to 15 years: an application of growth curve analysis.

The effect of lead exposure on cognitive growth patterns was assessed in a longitudinal study of 196 children. Performances on tests of verbal comprehension and perceptual organization (Vocabulary & Block Design, Wechsler Intelligence Scales for Children) were measured at ages 6.5, 11 and 15 years. Growth curve analyses revealed that the quadratic model best described the relationship between test scores and age. Children with higher lead levels, as measured at age 15 years, demonstrated lower verbal comprehension scores over time and greater decline in their rate of Vocabulary development at age 15 years, as compared to children with lower lead levels. Lead exposure was not significantly associated with growth in perceptual organization test scores. Socioeconomic status and maternal intelligence were statistically significantly associated with growth patterns for both test scores, independent of the effects of lead. The findings suggest that lead negatively impacts the developmental progression of specific cognitive skills from childhood through adolescence.