Predictive testing and oncogenes

Case vignette: sharing unanticipated genetic information. The Questor family has experienced an unusual number of malignancies in the past two generations and has been advised by an oncologist that the p53 oncogene known as Li-Fraumeni Syndrome may be present in the family genome. The option of predictive genetic testing has been raised and several branches of the family have chosen to undergo screening to determine whether they are at risk for cancer because of the gene. Roger and Liz Questor have arranged for screening of themselves and their three children, ages 12, 10, and 7. The couple has, by all appearances, been happily married for 14 years. None of the family members are found to carry the oncogene; however, the geneticist conducting the analyses has made an interesting incidental discovery. The 10-year-old child is not the biological progeny of Roger Questor. Although the 12- and 7-year-olds are clearly the biological children of the couple, it is evident that the 10-year-old born to Liz Questor was fathered by a person other than Roger. What are the ethical obligations of the geneticist with respect to any sharing or disclosure of the information that has been discovered incidentally? What course of action, if any, do you recommend?     

护士职业的人格特质研究

采用Ｙ－Ｇ性格测验问卷,对临床护士和在读护生共３９０人,进行了心理测评,展开了护士职业的人格特质研究。研究结果表明：优秀护士群体的性格类型和某些人格特质显著地优于一般护士群体;优秀护士与一般护士间所显现出显著差异的人格特质,对于护士角色人格的构成具有决定性影响;Ｙ－Ｇ性格测验的Ａ型性格类型评定对于护士职业的心理选拔显现特异性趋势;整个测评研究结果,基本支持＂护士个体人格特质与角色人格特质的匹配模式＂等理论假设．     

合作学习对小学生同伴关系、成就动机和成就影响的研究

旨在探讨在我国开展合作学习教学的可行性,以及合作学习对小学生同伴关系、成就动机和成就水平的影响,运用自然实验和测量相结合的方法,选择了北京师范大学实验小学三年级两个班进行实验研究,其中一个班为实验班（ｎ＝３５）,另一个班为控制班（ｎ＝３７）．实验为期三个月。结果表明：合作学习在小学教学中不但是可行的,而且效果较为显著;合作学习对同伴关系的改善有着积极的影响,学生间的接纳度和被接纳度都有普遍的提高;合作学习在较大程度上激发了学生的成就动机水平,学生对合作学习的课程兴趣明显提高．成绩较差的学生表现得更为明显;合作学习对提高学生的学习成绩有一定的促进作用。     

Differences in influence between pitched-from-vertical lines and slanted-from-frontal horizontal lines on egocentric localization

The visual field exerts powerful effects on egocentric spatial localization along both horizontal and vertical dimensions. Thus, (1) prism-produced visual pitch and visual slant generate similar mislocalizations of visually perceived eye level (VPEL) and visually perceived straight ahead (VPSA) and (2) in darkness curare-produced extraocular muscle paresis under eccentric gaze generates similar mislocalizations in VPEL and VPSA that are essentially eliminated by introducing a normal visual field. In the present experiments, however, a search for influences of real visual slant on VPSA to correspond to the influences of visual pitch on VPEL failed to find one. Although the elevation corresponding to VPEL changes linearly with the pitch of a visual field consisting of two isolated 66.5°-long pitched-from-vertical lines, the corresponding manipulation of change in the slant of either a horizontal two-line or a horizontal four-line visual field on VPSA did not occur. The average slope of the VPEL-versus-pitch function across 5 subjects was +0.40 over a ±30° pitch range, but was indistinguishable from 0.00 for the VPSA-versus-slant function over a ±30° slant range. Possible contributions to the difference between susceptibility of VPEL and VPSA to visual influence from extraretinal eye position information, gravity, and several retinal gradients are discussed.     

缺陷儿童人格诊断量表的修订

缺陷儿童人格诊断量表是日本特殊教育领域的一种专门用于测量缺陷儿童人格的著名量表。作者用三年时间对其进行了修订,建立了包括弱智、聋哑、盲等缺陷儿童的中国常模。该量表具有较高的信度与效度,是一个较好的心理测量工具。     

恐惧发生与预防的实验研究：──Ⅱ、强噪音下不同处理背景动物身心变化的观察分析

采用生理心理学的实验方法．对强噪音下四组不同处理背景大鼠的旷场反应、援食、饮水、排泄和尿生物化学等方面进行比较。结果发现：①Ⅰ组（强刺激组）的各类指标均发生情绪性（恐惧）改变。与２组（预防训练Ⅰ组）、３组（预防训练Ⅱ组）、４组（控制组）以及自身基线（ＭＡＯ）比较差异显著;②适应性训练有助于防止大鼠恐惧发生及上述各类指标发生异常．③由于训练的方法不同,预防的效果也不同。３组与４组比较无显著差异,２组与４组比较某些指标有显著差异。④１组和２组部分大鼠出现皮肤、消化道病变。     

Misalignment effects in 3-D versions of Poggendorff displays

Strong misalignment effects are found in three-dimensional (3-D) versions of Poggendorff displays viewed binocularly. The components of the standard 2-D Poggendorff figure—the parallels and the oblique segments—were presented in 3-D depth as a flat rectangular object with occluding edges and an oblique line situated behind the object. Three experiments investigated the misalignment effects under three different observation instructions: Subjects were told to look at the oblique (Experiment 1), at the rectangle (Experiment 2), or at the background (Experiment 3). Experiments 1 and 2 examined the effects on judgments of alignment of varying the distance in depth that separates the oblique from the rectangle. Experiment 3 examined the effects of varying the distance between the fixated background and the 3-D Poggendorff figure. Both standard and reversed misalignment effects were obtained. When the viewing condition produces crossed disparity for the oblique, perceived misalignment occurs in the usual Poggendorff direction, but it is reversed with uncrossed disparity. Moreover, the amount of misalignment is related to the amount of disparity, and it can be much stronger than is usual in the 2-D versions of the Poggendorff. The misalignment effects can be explained by binocular integration to produce a single cyclopean image.     

与年龄相关的认知速度减慢及学习改善过程

该工作应用人机对话方式完成心算、符号数字、数字鉴别和计数四项作业认知速度年老减慢及学习改善过程的研究,被试３５０人,４６—７５岁。研究结果表明：四项认知作业速度随年老进行性减慢;然而,老年人经学习训练认知作业速度可明显改善。上述变化程度与作业所需时间有密切关系,提示年老过程中枢信息加工过程速度的减慢快于外周感觉─运动过程速度的减慢,学习改善作用也可能主要是中枢过程速度的提高。     

非词语性认知作业速度年老衰减规律的数学描述

应用两维年龄多作业回归分析方法,研究了四项非词语性认知作业速度年老衰减规律的数学描述形式。被试共７３４名,４６─７５岁。结果表明：五个年老组与４６─５０岁组作业时间之间呈线性函数关系,其线性方程的斜率值随年老组的增龄而增大。     

The role of theory in treating adolescent substance abuse

The adolescent substance abuser, like adult addicts, is most commonly considered from the perspective of the disease model. The usefulness of the disease model in conceptualizing adolescent substance abuse is questioned, and an alternative view of the topic is set forth. Substance abuse, is regarded as an adaptive aspect of the ongoing interactive processes within the family. The developmental process of the adolescent substance abuser is seen as a functional dynamic in the family's preservation. Three characteristic elements of parental interaction common to the development of adolescent substance abuse are highlighted.An earlier version of this paper was presented at the Texas Association for Marriage and Family Therapy annual conference on January 28, 1993 in Houston Texas.a research associate and director of the Don D. Jackson Archive at the Mental Research Institute, Palo Alto, CA. Authors are listed alphabetically.