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We present an overview of two of our on-going projects relating processes in the hippocampus to memory. We are trying to understand why retrograde amnesia occurs after damage to the hippocampus. Our experiments establish the generality of several new retrograde amnesia phenomena that are at odds with the consensus view of the role of the hippocampus in memory. We show in many memory tasks that complete damage to the hippocampus produces retrograde amnesia that is equivalent for recent and remote memories. Retrograde amnesia affects a much wider range of memory tasks than anterograde amnesia. Normal hippocampal processes can interfere with retention of a long-term memory stored outside the hippocampus. We conclude that the hippocampus competes with nonhippocampal systems during memory encoding and retrieval. Finally, we outline a project to understand and manipulate adult hippocampal neurogenesis in order to repair damaged hippocampal circuitry to recover lost cognitive functions.  相似文献   
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Transcranial magnetic stimulation (TMS)-induced virtual lesions in healthy subjects can be used to test neurofunctional models of disease. The interhemispheric rivalry model of heminglect is well suited for such investigations, as simple predictions derived from clinical data can be tested without the caveats normally associated with lesion studies. One of these predictions is that release from contralateral inhibition should lead to increased parietal responsiveness, which, in turn, would enhance spatial attention. Here, we detail studies showing TMS-induced paradoxical functional facilitation of attention in healthy individuals and highlight their contribution to the understanding and treatment of neglect syndromes.  相似文献   
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Reasoning, defined as the production and evaluation of reasons, is a central process in science. The dominant view of reasoning, both in the psychology of reasoning and in the psychology of science, is of a mechanism with an asocial function: bettering the beliefs of the lone reasoner. Many observations, however, are difficult to reconcile with this view of reasoning; in particular, reasoning systematically searches for reasons that support the reasoner’s initial beliefs, and it only evaluates these reasons cursorily. By contrast, reasoners are well able to evaluate others’ reasons: accepting strong arguments and rejecting weak ones. The argumentative theory of reasoning accounts for these traits of reasoning by postulating that the evolved function of reasoning is to argue: to find arguments to convince others and to change one’s mind when confronted with good arguments. Scientific reasoning, however, is often described as being at odds with such an argumentative mechanisms: scientists are supposed to reason objectively on their own, and to be pigheaded when their theories are challenged, even by good arguments. In this article, we review evidence showing that scientists, when reasoning, are subject to the same biases as are lay people while being able to change their mind when confronted with good arguments. We conclude that the argumentative theory of reasoning explains well key features of scientists’ reasoning and that differences in the way scientists and laypeople reason result from the institutional framework of science.  相似文献   
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According to the limited strength model (Muraven, Tice & Baumeister, 1998), exerting self-control causes ego depletion: a depletion of cognitive resources resulting in poorer performance on later self-control tasks. Previous studies have demonstrated a positive effect of self-awareness on self-control performance. The present study examined whether the occurrence of ego depletion can be circumvented by increasing self-awareness. Initially depleted participants who received a neutral prime exhibited the classic ego depletion pattern: their performance on a subsequent physical self-control task decreased significantly. In contrast, no decrease in performance was observed for depleted participants who were exposed to a self-awareness prime. The latter group performed equally well compared to low depleted participants.  相似文献   
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The authors compare Black and White college student alcohol and other drug use. Significant differences were noted showing alcohol abuse to be less of a problem for Black students.  相似文献   
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