Effects of cocaine and alcohol, alone and in combination, on human learning and performance.

The acute effects of cocaine hydrochloride (4 to 96 mg/70 kg) and alcohol (0 to 1.0 g/kg), administered alone and in combination, were assessed in two experiments with human volunteers responding under a multiple schedule of repeated acquisition and performance of response chains. Subjects were intermittent users of cocaine and regular drinkers who were not cocaine or alcohol dependent. Alcohol was mixed with orange juice and ingested in six drinks within 30 min; cocaine was administered intranasally 45 min after completion of drinking. In each component of the multiple schedule, subjects completed response sequences using three keys of a numeric keypad. In the acquisition component, a new sequence was learned each session. In the performance component, the response sequence always remained the same. Results were consistent in both experiments, despite variations in the order in which the drugs were tested alone and in combination. Alcohol administered alone increased overall percentage of errors and decreased rates of responding in the acquisition component, whereas responding in the performance component generally was unaffected. Cocaine administered alone decreased rates of responding but did not affect accuracy of responding in the acquisition component, and enhanced accuracy of responding without affecting rates of responding in the performance component. The combined doses of cocaine and alcohol attenuated the effects observed with alcohol and cocaine alone. These results suggest that, under the conditions investigated in this study, (a) alcohol produces greater behavioral disruption than cocaine or cocaine-alcohol combinations, (b) cocaine and alcohol each attenuate effects of the other, and (c) such attenuation is most pronounced for cocaine attenuating the disruptive effects of alcohol.     

Intervention for Children Exposed to Interparental Violence (IPV): Assessment of Needs and Research Priorities

In this paper we review the development of interventions for children who have been exposed to interparental violence (IPV), assess current needs in the evaluation of interventions, and provide suggestions for research priorities in this area. Interventions for negative outcomes associated with exposure to IPV only recently have been carefully designed and evaluated, thus knowledge regarding program effectiveness is minimal. Three of the most comprehensive interventions that have been evaluated are presented. Each has demonstrated effectiveness, and focuses on children with different levels of symptoms and distress. However, many questions remain regarding which interventions are beneficial for diverse children with different kinds and intensities of problems. A number of research priorities and suggestions for further improvements in the evaluation of effectiveness of interventions are identified.     

An assessment of cerebral dominance in language-disordered children via a time-sharing paradigm

A time-sharing paradigm was used to assess language lateralization in language-disordered and normal children aged 4–7 years. Several expressive language tasks as well as a vocal, but nonlinguistic, task were administered concurrently with unimanual finger tapping. Dependent variables were percent disruption scores and number of syllables produced per concurrent trial. All language concurrent tasks produced tapping reductions for both hands for both groups. This result contrasts to similar time-sharing studies claiming asymmetrical interference and hence language lateralization in children (N. White & M. Kinsbourne, 1980, Brain and Language, 10, 215–223; J. Obrzut, G. Hynd, A. Obrzut, & J. Leitgeb, 1980, Brain and Language, 11, 181–194). A multiple regression analysis revealed a significant interaction effect differentiating language-disordered from normal children. Normals exhibited a parallel response pattern for speech and tapping (both increased or decreased in rate) under all lateralization conditions. Language-disordered children exhibited an inverse response pattern (e.g., if speech output increased, tapping rate decreased) only under left-hemisphere time-sharing.     

Stereotyping and victim blaming of individuals with a laryngectomy

This study examined whether individuals with a laryngectomy are at risk for stereotyping and victim blaming. Undergraduate students (3 men and 41 women) volunteered to listen to a recording of a man who used tracheoesophageal speech or a man who was a typical adult speaker. A written vignette was provided prior to the listening activity to assess whether knowing that the speaker did or did not have a history of smoking affected the listeners' judgments of the speaker. Semantic differential data and qualitative responses indicated that participants did not report victim blaming; however, they did report that users of tracheoesophageal speech were less highly employable than typical adult speakers. Participants also indicated they relied on the vocal characteristics of speakers and used empathy- or experienced-based reactions to make judgments about users of such speech.     

Alternatives to switch-cost scoring in the task-switching paradigm: Their reliability and increased validity

In the task-switching paradigm, the latency switch-cost score—the difference in mean reaction time between switch and nonswitch trials—is the traditional measure of task-switching ability. However, this score does not reflect accuracy, where switch costs may also emerge. In two experiments that varied in response deadlines (unlimited vs. limited time), we evaluated the measurement properties of two traditional switch-cost scoring methods (the latency switch-cost score and the accuracy switch-cost score) and three alternatives (a rate residual score, a bin score, and an inverse efficiency score). Scores from the rate residual, bin score, and inverse efficiency methods had comparable reliability for latency switch-cost scores without response deadlines but were more reliable than latency switch-cost scores when higher error rates were induced with a response deadline. All three alternative scoring methods appropriately accounted for differences in accuracy switch costs when higher error rates were induced, whereas pure latency switch-cost scores did not. Critically, only the rate residual and bin score methods were more valid indicators of task-switching ability; they demonstrated stronger relationships with performance on an independent measure of executive functioning (the antisaccade analogue task), and they allowed the detection of larger effect sizes when examining within-task congruency effects. All of the three alternative scoring methods provide researchers with a better measure of task-switching ability than do traditional scoring methods, because they each simultaneously account for latency and accuracy costs. Overall, the three alternative scoring methods were all superior to the traditional latency switch-cost scoring method, but the strongest methods were the rate residual and bin score methods.     

Role of resilient personality on lower achieving first grade students' current and future achievement

This study investigated a measurement model of personality resilience and the contribution of personality resilience to lower achieving first grade students' academic achievement. Participants were 445 ethnically diverse children who at entrance to first grade scored below their school district median on a test of literacy. Participants were administered an individual achievement test in first grade and 1 year later. Confirmatory factor analysis confirmed a second-order latent construct of resilient personality defined by teacher-rated conscientiousness, agreeableness, and ego-resiliency that was distinct from measures of externalizing behaviors and IQ. Using latent structural equation modeling and controlling for baseline economic adversity, IQ, and externalizing symptoms, resilient personality predicted children's concurrent and future achievement (controlling also for baseline achievement in the prospective analyses). Model fit was invariant across gender.     

Interpreting inclusion: A contribution to the study of the child's cognitive and linguistic development

Six experiments are reported which examine the young child's ability to compare included and nonincluded sets. Results indicate that with certain forms of task presentation most 3- to 5-year-old children can compare part with whole. Further, errors which occur in inclusion tasks are similar to errors which occur in tasks involving comparison of nonincluded sets. Thus young children can solve inclusion problems, and their customary failure to do so does not arise because the problem requires comparison of a whole with an included part. Employing a distinction between intended tasks (those which the adult wishes the child to complete) and received tasks (those which the child, in fact, completes) the studies indicate how linguistic and perceptual aspects of the presented information may interact with the child's assumptions about the nature of the task to be completed.     

Fluorescent lighting: A purported source of hyperactive behavior

Seven first-grade children with conduct disorders and/or hyperactivity attended full-day sessions at a laboratory school classroom. During an 8- week period, the classroom lighting conditions alternated at the end of each week. During oddnumbered weeks, the classroom was illuminated by a standard coolwhite fluorescent system. On even-numbered weeks, illumination was a daylightsimulating fluorescent system of equal footcandles with controls for purported soft X rays and radio frequency (RF). There were no effects of lighting conditions on hyperactive behavior as assessed by (a) independent observations of task orientation or (b) ratings of activity level. A Critical Flicker Fusion (CFF) measure, a reported indicator of visual-sensory fatigue, indicated that the daylight-simulating condition was associated with a decreasing CFF across weeks.This research was a joint endeavor initiated by Alan Rosenbaum and directed by Dr. Daniel O'Leary. Dr. Philip Hughes and Mr. Frank LaGuisa and their associates at the General Electric Lighting Development Section consulted with us in all phases regarding lighting and electromagnetic radiation. We are very grateful to Dr. Susan O'Leary, director, and Marlene Schneider, head teacher, of the University Laboratory School, where this study was conducted. Special thanks go to Mark Durand, Ruth Shepard, and Michael Mignone, who contributed to variousphases of this study. The observers were Wilma Meyers and Frank Tucci. This research was supported in part by General Electric and in part by the State University of New York, Stony Brook. Detailed technical information concerning the lighting and measurement is available in a full text from the authors.     

Assessing pain behaviour of low-back pain patients in real time: concurrent validity and examiner sensitivity

Several systems for measuring pain behaviour have been developed for clinical settings. The present study reports on a real-time system for coding five categories of pain behaviour for low-back pain patients: guarding, touching, sounds, words, and facial expression. Unique features of the system are the use of refined measures of facial expression and integration of the measurements with a standardized physical examination. 176 sub-acute and chronic low-back pain patients underwent a physical examination while their pain behaviour was coded. Concurrent measures of subjective pain, medically-incongruent signs, and independent global ratings of pain behaviour were taken. Analyses indicated that the pain behaviours, particularly guarding and facial expression, varied systematically with the alternative measures, supporting the concurrent validity of the behaviour observation system. While pain behaviours, especially use of words and facial expressions, were significantly associated with the examiners' independent ratings, the strength of the associations suggested that, in the absence of direct training, examiners' performance was relatively poor. Implications for training of clinicians in detecting pain behaviour are discussed.