Effects of COMT genotype on behavioral symptomatology in the 22q11.2 Deletion Syndrome.

The 22q11.2 Deletion Syndrome (DiGeorge/velocardiofacial syndrome) is associated with elevated rates of psychosis, and is also characterized by severe attentional difficulties and executive dysfunction. Behavioral manifestations of this syndrome could result from haploinsufficiency of the catechol-O-methyltransferase (COMT) gene, located within the 22q11 region. The goal of the present study was to examine COMT genotype in relation to behavioral symptomatology in this syndrome. Val158/108Met was genotyped in 38 patients (16 Met/-, 22 Val/-) with confirmed 22q11.2 deletions who had received the Child Behavior Checklist (CBCL) as part of a comprehensive evaluation. Results indicated that the Val genotype was associated with significantly greater internalizing and externalizing behavioral symptomatology in children with 22q11.2 deletions. Val allele status was associated with a greater-than-four-fold increase in risk for clinically significant behavior problems in children with this syndrome. These data are consistent with previous findings of increased psychopathology associated with the Val genotype in normal individuals and suggest that a functional genetic polymorphism in the 22q11 region may influence behavior in individuals with COMT haploinsufficiency.     

Defensive Responding on the MMPI-2 in Pre-Surgical Candidates

The MMPI-2 is frequently used for a variety of pre-surgical evaluations that can have life changing consequences for the patient being examined. While it intuitively makes sense that a proportion of examinees will attempt to downplay distress in order to avoid any perceived questions about their surgical candidacy, this hypothesis has received scant research attention. This study cluster analyzed the MMPI-2 L, F, & K validity scales for 890 pre-surgical candidates. Depending on the standard utilized, between one-third and two-thirds of our sample displayed some degree of defensive responding. These results suggest that traditional markers of test validity may need to be adjusted in populations with high base rates for defensiveness. The difficulty in ascribing personality characteristics based on validity scale scores and directions for further research are also discussed.     

Meanings of Education for University Students: Academic Motivation and Personal Values as Predictors

We conducted two studies to determine the meanings that undergraduate students ascribe to their education and how these meanings relate to relevant psychological constructs: academic motivation and values. Ten meanings emerged: career preparation, independence, finding direction for the future, learning, self-development, taking the next step, making social connections, changing the world, stress, and escape. Support was found for many of the predicted relationships. For example, enjoyment motivation positively predicted all of the meanings, except taking the next step, stress, and escape. Also as expected, the values of intellectualism and academic achievement positively predicted learning, self-development, and changing the world. However, contrary to expectations, valuing physical development also emerged as a significant predictor of several of the meanings of education.     

Three kinds of rhymes: An ERP study

In a simple prime-target visual rhyming paradigm, pairs of words, nonwords, and single letters elicited similar event-related potential (ERP) rhyming effects in young adults. Within each condition, primes elicited contingent negative variation (CNV) while nonrhyming targets elicited more negative waveforms than rhyming targets within the 320-500ms (N400/N450) time window. The target rhyming effect, apparently primarily an index of phonological processing, was similar across conditions but tended to be smaller in mean amplitude for letters. One of the first reports of such a letter rhyming effect in the ERP literature, these findings could be important developmentally because letter rhyme tasks simultaneously index the two best predictors of ease of learning to read: letter name knowledge and phonological awareness.     

Feminist Consciousness Among Russians and Americans

Most empirical research on feminist consciousness has been conducted with North American women. In this study we examined feminist consciousness and attitudes toward women's issues among Russian and American women and men. Survey data from undergraduate students provide evidence of both cross-cultural and gender-related differences. Women scored higher than men on 4 of the 5 aspects of feminist consciousness measured in this study. American students scored higher on three aspects of feminist consciousness; however, Russian students were higher on sensitivity to sexism. Data concerning attitudes toward specific women's issues are also presented. Findings suggest that judgments about feminist consciousness based solely on these attitudes could lead to misconceptions about levels of feminist consciousness across cultures.     

A Relational Approach to Career Counseling: Theoretical Integration and Practical Application

This article reviews the current status of career theory in practice and presents a theoretical overview of relational theory and its logical extension to the career domain. Despite the emergence of literature regarding the interconnectedness of career progress and the quality of relationships in one's life (e.g., D. L. Blustein, 2001; D. L. Blustein, M. S. Prezioso, & D. E. P. Schultheiss, 1995; D. E. P. Schultheiss, H. M. Kress, A. J. Manzi, & J. M. Glasscock, 2001), counseling practice is limited by the absence of a meaningful approach to intervene in clients' relational and career worlds. The relational career counseling approach moves counseling toward a contextually based relational perspective to facilitating career progress. This approach is illustrated with a case example.     

MATERIALISM, SOCIOCULTURAL APPEARANCE MESSAGES, AND PATERNAL ATTITUDES PREDICT COLLEGE WOMEN'S ATTITUDES ABOUT COSMETIC SURGERY

Rates of cosmetic surgery procedures have increased dramatically over the past several decades, but only recently have studies of cosmetic surgery attitudes among the general population begun to appear in the literature. The vast majority of those who undergo cosmetic surgery are women. We examined cosmetic surgery attitudes among 218 undergraduate women, most of whom were White. Specifically, we examined their acceptance of cosmetic surgery and expressed desire to undergo cosmetic surgery procedures, and several potential predictors: appearance attitudes of mothers, fathers, and friends; awareness and internalization of sociocultural appearance messages; and materialism. Multiple regression analyses indicated that materialism and internalization of sociocultural messages consistently emerged as significant predictors of acceptance of cosmetic surgery and desire for cosmetic surgery procedures. Paternal attitudes positively predicted acceptance of cosmetic surgery for social reasons and desire for cosmetic surgery; nonmaterialism negatively predicted considering cosmetic surgery and the desire for cosmetic surgery procedures.     

Hiding and finding: The relationship between visual concealment and visual search

As an initial step toward developing a theory of visual concealment, we assessed whether people would use factors known to influence visual search difficulty when the degree of concealment of objects among distractors was varied. In Experiment 1, participants arranged search objects (shapes, emotional faces, and graphemes) to create displays in which the targets were in plain sight but were either easy or hard to find. Analyses of easy and hard displays created during Experiment 1 revealed that the participants reliably used factors known to influence search difficulty (e.g., eccentricity, target—distractor similarity, presence/absence of a feature) to vary the difficulty of search across displays. In Experiment 2, a new participant group searched for the targets in the displays created by the participants in Experiment 1. Results indicated that search was more difficult in the hard than in the easy condition. In Experiments 3 and 4, participants used presence versus absence of a feature to vary search difficulty with several novel stimulus sets. Taken together, the results reveal a close link between the factors that govern concealment and the factors known to influence search difficulty, suggesting that a visual search theory can be extended to form the basis of a theory of visual concealment.     

The effect of ethanol treatment on social behavior in male rats

The effect of 0.50 g/kg of EtOH in male rats interacting with a stimulus male juvenile in a newly developed test of social interaction was examined. The adult male rats were treated with EtOH (8.0 to 12.0 g/kg/day) or equicaloric dextrin maltose for 2 weeks (studies 1 and 2) or 8 weeks (study 3) and social interaction was assessed both before and after chronic drug treatment was ended in study 1 and after chronic drug treatment was ended in studies 2 and 3. It was found that prior to chronic drug treatment, in study 1, 0.50 g/kg of EtOH increased both aggressive behavior and time spent interacting with the stimulus juvenile male from the first presentation of the juvenile to the second presentation (20 min apart) while saline injection decreased it. After chronic drug treatment was ended, in study 1 animals treated chronically with EtOH were more aggressive when they were not intoxicated than when they had been treated with 0.50 g/kg of EtOH. In studies 2 and 3, after chronic drug treatment was ended, aggressive behavior and time spent interacting with the juvenile were greater in the animals treated chronically with EtOH, regardless of whether they were injected with saline or 0.50 g/kg of EtOH. The results of these studies showed that chronic EtOH treatment can produce long-lasting changes in social behavior after drug treatment is over and can alter the animal's normal response to EtOH in a social setting.