论个体差异与诊疗决策

诊疗决策最优化的过程,本质上是针对特定的患者,制定最适合其个体差异的决策过程.对个体差异认知方式,经验医学基于对个体的不完全归纳,循证医学基于对群体随机、双盲、对照、大样本,人类基因组学基于对人类基因的差异表达、单核苷酸多态和复制变异的研究.最优化的治疗方案应体现关注患者心理、社会差异、关注生命质量、远离趋利性等人文特征;体现针对个体病患生物学特性差异、个体病程病期和个体最佳疗效差异等科学特征.     

满川风雨看潮生——《医学与哲学》激流勇进30年

30年来,<医学与哲学>立足于医学哲学之形而上的思想高地,关注医学发展重大问题,铸造医学人文精神;为我国医学事业的发展提供正确的导向和精神动力;矢志不移地致力于我国人文社会医学的学科建设,将学术期刊建构成为全国性的人文社会医学高端学术平台.<医学与哲学>形成的特色和业绩,构成了值得关注和研究的"<医学与哲学>现象".     

Anticipating intentional actions: The effect of eye gaze direction on the judgment of head rotation

Using a representational momentum paradigm, this study investigated the hypothesis that judgments of how far another agent’s head has rotated are influenced by the perceived gaze direction of the head. Participants observed a video-clip of a face rotating 60° towards them starting from the left or right profile view. The gaze direction of the face was either congruent with, ahead of, or lagging behind the angle of rotation. Following this, two static faces, at varying angles of rotation with respect to the end-point angle of the face in the video-clip, were presented simultaneously. The task of the participants was to decide which of the two heads was at an angle best resembling the angle of the end-point of the moving face. The critical test condition consisted of one test face oriented at 10° before, and the other at 10° after the end-point. The ‘lagging behind’ gaze condition elicited a significant underestimation of the rotation compared to the ‘congruent’ and ‘ahead’ gaze conditions. Participants did not exhibit similar biases when judging the rotation of several non-face control stimuli with visual features that mimicked different aspects of gaze direction. The findings suggest that when the gaze direction of a perceived agent is incongruent with the direction of the agent’s head motion observers automatically utilise this discrepancy to adjust their inferences about the agent’s intended heading direction.     

Self‐esteem as a source of evaluative conditioning

This study was designed to examine whether self‐esteem can be used as a source of evaluative conditioning, and whether implicit or explicit self‐esteem was more predictive of the evaluative conditioning effect. Moreover, the role of contingency awareness in the acquisition of the evaluative conditioning effect was also examined. Words related to the self and a general other were served as unconditioned stimuli (USs) in the evaluative conditioning process in order to see whether the evaluation could be transferred to neutral, abstract paintings after 10 times of pairing. An evaluative conditioning effect was demonstrated in that the evaluation of the paintings became more positive after repeatedly paired with words about the self but not words about general others. Implicit self‐esteem predicted the magnitude of the evaluative conditioning effect, while the association between explicit self‐esteem and the evaluative conditioning effect was nonsignificant, both with and without the effect of contingency awareness being controlled for. Copyright © 2009 John Wiley & Sons, Ltd.     

大学生学习适应量表的编制

对当代大学生学习适应问题进行了深入分析,在有关研究的基础上,探讨了当代大学生学习适应的主要因素,并编制一套适合当代大学生学习适应的测验。对四类院校918名大学生进行了施测,对调查数据进行了探索性因素分析和验证性因素分析。探索性因素分析结果表明,大学生学习适应的主要因素包括学习动机、教学模式、学习能力、学习态度、环境因素等5个方面;验证性因素分析结果表明,所提取的5个因素与构想模型拟合较好,测验具有较好的信、效度     

自我超越生命意义对压力和健康关系的调节作用

研究目的是检验一个新的应激应对资源—自我超越生命意义的健康调节作用。自我超越生命意义的理论基础是东方的佛教哲学和道家哲学。研究的测量工具有：大学校园压力量表,一般健康问卷（GHQ-20）,自尊量表和自我超越生命意义量表。被试为来自北京市三所高校的788名大学生。研究结果为：自我超越生命意义可以调节应激条件下的忧郁情绪、一般健康问题和自尊,但是对于焦虑情绪和自我肯定的调节作用不明显。研究结论是：自我超越生命意义对心理健康的某些方面具有调节作用     

5岁儿童能够理解假装的心理表征:对Moe任务的质疑

本研究通过三个实验对Lillard的Moe假装任务进行了重复与改进,旨在探讨儿童对假装行为中知识状态作用的理解,进而讨论儿童对假装的心理本质的理解。实验一表明,“是否”问题使得5岁儿童在该任务上表现出肯定回答倾向;实验二表明．当改变提问方式,在问题中提供选择项目后,5岁儿童在该任务上的通过率有显著提高．肯定回答倾向明显减弱;实验三表明,当减少指导语中相互矛盾的信息、明确指出主人公知道某物而不知道另一物以及减弱对未知状态和知道状态的强调的情况下．5岁儿童能根据主人公所知道的事物来推断出其行为是在假装成该事物,能理解到知识状态在假装行为中的作用。这一结果表明5岁儿童能够理解到假装中所隐含的心理表征,Lillard所提出的Moe任务范式低估了儿童对假装的心理本质的理解能力。     

工作绩效的结构及其与胜任特征的关系

本研究旨在验证党政领导干部对下级工作绩效评定的结构,并探讨其与胜任特征之间的关系。两个省市的450名党政领导干部完成了对自己下级的工作绩效和胜任特征的评定。结果表明,评定下级干部工作绩效的两因素结构,即任务指向和个人素质,得到了验证;分别以工作绩效的两个二阶因素为因变量,以胜任特征的七个维度为预测变量进行逐步回归分析,胜任特征可以解释工作绩效的“才”和“德”成分54．5％和55．3％的变异。胜任特征和工作绩效中“德”和“才”的成分之间存在复杂的关系,既可以相互促进,也可以交互抑制。文中还对这一结果的含义及本土化研究的意义进行了深入讨论。     

序数表征及其脑机制

人类天生就具有一些初级的数概念。研究表明,顶内沟是基数表征的脑基础,这一区域受损或发展受阻将导致计算失能等与数有关的认知障碍。尽管序数与基数存在相似的行为效应,但与序数相联系的皮层通路不同于基数,序数表征主要激活前额皮层与颞叶皮层区域。序数是否也存在符号效应以及跨文化差异等问题有待进一步研究