Expansion of Genetic Services Utilizing a General Genetic Counseling Clinic

We established a general genetic counseling clinic (GCC) to help reduce long wait times for new patient appointments and to enhance services for a subset of patients. Genetic counselors, who are licensed in Tennessee, were the primary providers and MD geneticists served as medical advisors. This article describes the clinic referral sources, reasons for referral and patient dispositions following their GCC visit(s). We obtained patients by triaging referrals made to our medical genetics division. Over 24 months, our GCC provided timely visits for 321 patients, allowing the MD geneticists to focus on patients needing a clinical exam and/or complex medical management. Following their GCC visit(s), over 80 % of patients did not need additional appointments with an MD geneticist. The GCC allowed the genetic counselor to spend more time with patients than is possible in our traditional medical genetics clinic. Patient satisfaction surveys (n?=?30) were very positive overall concerning the care provided. Added benefits for the genetic counselors were increased professional responsibility, autonomy and visibility as health care providers. We conclude that genetic counselors are accepted as health care providers by patients and referring providers for a subset of clinical genetics cases. A GCC can expand genetic services, complement more traditional genetic clinic models and utilize the strengths of the genetic counselor health care provider.     

Inverse effectiveness, multisensory integration, and the bodily self: Some statistical considerations

A recent report in Consciousness and Cognition provided evidence from a study of the rubber hand illusion (RHI) that supports the multisensory principle of inverse effectiveness (PoIE). I describe two methods of assessing the principle of inverse effectiveness (‘a priori’ and ‘post-hoc’), and discuss how the post-hoc method is affected by the statistical artefact of ‘regression towards the mean’. I identify several cases where this artefact may have affected particular conclusions about the PoIE, and relate these to the historical origins of ‘regression towards the mean’. Although the conclusions of the recent report may not have been grossly affected, some of the inferential statistics were almost certainly biased by the methods used. I conclude that, unless such artefacts are fully dealt with in the future, and unless the statistical methods for assessing the PoIE evolve, strong evidence in support of the PoIE will remain lacking.     

Illusory recollection of voices

We investigated source misattributions in the DRM false memory paradigm (Deese, 1959, Roediger & McDermott, 1995). Subjects studied words in one of two voices, manipulated between‐lists (pure‐voice lists) or within‐list (mixed‐voice lists), and were subsequently given a recognition test with voice‐attribution judgements. Experiments 1 and 2 used visual tests. With pure‐voice lists (Experiment 1), subjects frequently attributed related lures to the corresponding study voice, despite having the option to not respond. Further, these erroneous attributions remained high with mixed‐voice lists (Experiment 2). Thus, even when their related lists were not associated with a particular voice, subjects misattributed the lures to one of the voices. Attributions for studied items were fairly accurate in both cases. Experiments 3 and 4 used auditory tests. With pure‐voice lists (Experiment 3), subjects frequently attributed related lures and studied items to the corresponding study voice, regardless of the test voice. In contrast, with mixed‐voice lists (Experiment 4), subjects frequently attributed related lures and studied items to the corresponding test voice, regardless of the study voice. These findings indicate that source attributions can be sensitive to voice information provided either at study or at test, even though this information is irrelevant for related lures.     

Occurrence of imagery and its link with early memories in agoraphobia

Recent cognitive models suggest that mental imagery can help us understand the maintenance of anxiety disorders (e.g., de Silva, 1986; Hackmann, Surawy, & Clark, 1998). However, imagery is relatively unexplored within agoraphobia. Such images are also thought to be useful in uncovering memories that occurred around the onset of a disorder (Hackmann, Clark, & McManus, 2000). A total of 20 patients with agoraphobia and 20 matched controls took part in this investigation. Participants described any recurrent images they experienced in agoraphobic situations, and also any associated memories. All patients with agoraphobia (but no control participants) reported having distinct recurrent images in “agoraphobic situations”. Most images involved several sensory modalities and in the majority of cases appeared to be linked with unpleasant memories of events experienced many years previously. While these exploratory findings require replication, potential treatment implications are discussed.     

Fostering relationship resilience: An intervention for low self-esteem individuals

Low self-esteem individuals (LSEs) tend to react to relationship threats with self-protective and relationship-destructive behaviors that decrease their partners’ satisfaction with the relationship over time (Murray, Bellavia, Rose, & Griffin, 2003). In the current studies, we examined the effects of a theoretically driven intervention on LSEs’ relationship-destructive responses to threats. Participants were induced to reframe their partners’ compliments in a more abstract, meaningful way (the “abstract reframing intervention” or ARI), an intervention that has been shown to increase LSEs’ security in their relationships (Marigold, Holmes, & Ross, 2007). In Study 1, the ARI prevented LSEs from exaggerating the significance of relationship threats and self-protectively derogating their relationship (reported by LSEs in a one-time experimental situation). In Study 2, the ARI reduced LSEs negative, critical behaviors towards their partners (reported by LSEs’ partners for a 2-3 week period). The findings have important implications for breaking the self-fulfilling cycle of insecurity.     

Reflecting on imagery: a clinical perspective and overview of the special issue of memory on mental imagery and memory in psychopathology

The authors provide an overview of the papers in the special issue of Memory on mental imagery and memory in psychopathology. The papers address emotional, intrusive mental imagery across a range of psychological disorders including post-traumatic stress disorder (PTSD), agoraphobia, body dysmorphic disorder, mood disorders, and psychosis. They include work on information processing issues including modelling cravings, conditioning, and aversions, as well as imagery qualities such as vividness and emotionality. The overview aims to place the articles in a broader context and draw out some exciting implications of this novel work. It provides a clinical context to the recent growth in this area from a cognitive behavioural therapy (CBT) perspective. We begin with PTSD, and consider links to imagery in other disorders. The clinical implications stemming from this empirical work and from autobiographical memory theory are discussed. These include consideration of a variety of techniques for eliminating troublesome imagery, and creating healthy, realistic alternatives.     

Paradoxes in Double Extension Set Theories

Three systems of double extension set theory have been proposed by Andrzej Kisielewicz in two papers. In this paper, it is shown that the two stronger systems are inconsistent, and that the third, weakest system does not admit extensionality for general sets or the use of general sets as parameters in its comprehension scheme. The parameter-free version of the comprehension principle of double extension set theory is also shown to be inconsistent with extensionality. The definitions of the systems and a self-contained exposition of their properties is given, sufficient to develop the inconsistency proofs.     

English semantic word-pair norms and a searchable Web portal for experimental stimulus creation

As researchers explore the complexity of memory and language hierarchies, the need to expand normed stimulus databases is growing. Therefore, we present 1,808 words, paired with their features and concept–concept information, that were collected using previously established norming methods (McRae, Cree, Seidenberg, & McNorgan Behavior Research Methods 37:547–559, 2005). This database supplements existing stimuli and complements the Semantic Priming Project (Hutchison, Balota, Cortese, Neely, Niemeyer, Bengson, & Cohen-Shikora 2010). The data set includes many types of words (including nouns, verbs, adjectives, etc.), expanding on previous collections of nouns and verbs (Vinson & Vigliocco Journal of Neurolinguistics 15:317–351, 2008). We describe the relation between our and other semantic norms, as well as giving a short review of word-pair norms. The stimuli are provided in conjunction with a searchable Web portal that allows researchers to create a set of experimental stimuli without prior programming knowledge. When researchers use this new database in tandem with previous norming efforts, precise stimuli sets can be created for future research endeavors.