Inverse effectiveness, multisensory integration, and the bodily self: Some statistical considerations

A recent report in Consciousness and Cognition provided evidence from a study of the rubber hand illusion (RHI) that supports the multisensory principle of inverse effectiveness (PoIE). I describe two methods of assessing the principle of inverse effectiveness (‘a priori’ and ‘post-hoc’), and discuss how the post-hoc method is affected by the statistical artefact of ‘regression towards the mean’. I identify several cases where this artefact may have affected particular conclusions about the PoIE, and relate these to the historical origins of ‘regression towards the mean’. Although the conclusions of the recent report may not have been grossly affected, some of the inferential statistics were almost certainly biased by the methods used. I conclude that, unless such artefacts are fully dealt with in the future, and unless the statistical methods for assessing the PoIE evolve, strong evidence in support of the PoIE will remain lacking.     

Intracranial EEG power spectra and phase synchrony during consciousness and unconsciousness

Power density spectra and phase synchrony measurements were taken from intracranial electrode grids implanted in epileptic subjects. Comparisons were made between data from the waking state and from the period of unconsciousness immediately following a generalised tonic–clonic seizure. Power spectra in the waking state resembled coloured noise. Power spectra in the unconscious state resembled coloured noise from 1 to about 5 Hz, but at higher frequencies changed in two out of three subjects to resemble white noise. This boosted unconscious gamma power to a higher level than conscious gamma power. For both gamma and beta passbands, synchrony measurements showed more widespread phase synchrony in the unconscious than the conscious state. We conclude that neither gamma activity per se nor phase synchrony per se are neural correlates of consciousness.     

EMERGENCE OF TACTS FOLLOWING MAND TRAINING IN YOUNG CHILDREN WITH AUTISM

This study sought to examine the effects of training mands on the emergence of tacts with the same response forms. Results indicated that training adjective sets as mands resulted in the emergence of adjective sets as tacts under modified, but not standard, antecedent conditions. The findings suggested that the apparent functional independence of mands and tacts may be explained by a lack of appropriate antecedent control over responding.     

When less is more: An exploration of psychoanalytically oriented hospital‐based treatment for severe personality disorder4

This paper discusses the main findings of a prospective study based at the Cassel Hospital, a centre dedicated to the psychoanalytically informed residential treatment of severe personality disorders. The results‐showing that significantly greater improvements on a number of outcome indicators were found in patients exposed to the psychoanalytically informed treatment programmes compared to a general psychiatric approach based on management and pharmacotherapy alone‐underscores the importance and the centrality of the psychoanalytic input in the treatment of severe personality disorders. However, the results of the study also suggested that some features of long‐term hospital treatment might carry the risk of iatrogenic and anti‐therapeutic effects for a sub‐group of patients with severe borderline core pathology. The authors present the clinical and psychodynamic implications of the study results based on an understanding of the internal and interpersonal mode of functioning of borderline patients.     

Yohimbine impairs extinction of cocaine-conditioned place preference in an alpha2-adrenergic receptor independent process

Extinction, a form of learning that has the ability to reshape learned behavior based on new experiences, has been heavily studied utilizing fear learning paradigms. Mechanisms underlying extinction of positive-valence associations, such as drug self-administration and place preference, are poorly understood yet may have important relevance to addiction treatment. Data suggest a major role for the noradrenergic system in extinction of fear-based learning. Employing both pharmacological and genetic approaches, we investigated the role of the alpha(2)-adrenergic receptor (alpha(2)-AR) in extinction of cocaine-conditioned place preference (CPP) and glutamatergic transmission in the bed nucleus of the stria terminalis (BNST). We found that pre-extinction systemic treatment with the alpha(2)-AR antagonist yohimbine impaired cocaine CPP extinction in C57BL/6J mice, an effect that was not mimicked by the more selective alpha(2)-AR antagonist, atipamezole. Moreover, alpha(2A)-AR knockout mice exhibited similar cocaine CPP extinction and exacerbated extinction impairing effects of yohimbine. Using acute brain slices and electrophysiological approaches, we found that yohimbine produces a slowly evolving depression of glutamatergic transmission in the BNST that was not mimicked by atipamezole. Further, this action was extant in slices from alpha(2A)-AR knockout mice. Our data strongly suggest that extinction-modifying effects of yohimbine are unlikely to be due to actions at alpha(2A)-ARs.     

The Quality of Response Time Data Inference: A Blinded,Collaborative Assessment of the Validity of Cognitive Models

Psychonomic Bulletin & Review - Most data analyses rely on models. To complement statistical models, psychologists have developed cognitive models, which translate observed variables into...     

Social acceptance and self-esteem: tuning the sociometer to interpersonal value

The authors draw on sociometer theory to propose that self-esteem is attuned to traits that garner others' acceptance, and the traits that garner acceptance depend on one's social role. Attunement of self-esteem refers to the linkage, or connection, between self-esteem and specific traits, which may be observed most clearly in the association between self-esteem and specific self-evaluations. In most roles, appearance and popularity determine acceptance, so self-esteem is most attuned to those traits. At the same time, interdependent social roles emphasize the value of communal qualities, so occupants of those roles have self-esteem that is more attuned to communal qualities than is the general norm. To avoid the biases of people's personal theories, the authors assessed attunement of self-esteem to particular traits indirectly via the correlation between self-esteem and self-ratings, cognitive accessibility measures, and an experiment involving social decision making. As hypothesized, self-esteem was generally more attuned to appearances than to communal qualities, but interdependent social roles predicted heightened attunement of self-esteem to qualities like kindness and understanding.     

Patient perceptions of factors influencing adherence to medication following kidney transplant

Research has shown that most patients with end-stage kidney failure prefer treatment by transplantation. This entails taking immunosuppressant drugs daily throughout the life of the kidney. Failure to do so causes transplant rejection and a return to dialysis, or sometimes even death. Up to 50% of transplanted patients report failing to take their medication as prescribed. This qualitative study used focus groups to explore patients' lived experience in relation to medication adherence. Data were analysed using thematic analysis. The main themes to emerge were: fear of kidney failure, loyalty to the renal team and donors, health beliefs, forgetting and side-effects. Reasons for adherence were to avoid kidney failure and to acknowledge their gratitude to the renal team and donors. Participants suggested that non-adherence was largely due to forgetting.     

Task feedback effects on conflict monitoring and executive control: relationship to subclinical measures of depression

Emerging evidence suggests that depression is associated with executive dysfunction, particularly after committing errors or receiving negative performance feedback. To test this hypothesis, 57 participants performed two executive tasks known to elicit errors (the Simon and Stroop Tasks) during positive or negative performance feedback. Participants with elevated depressive symptoms (Beck Depression Inventory scores >or= 13) were characterized by impaired posterror and postconflict performance adjustments, especially during emotionally negative task-related feedback. Additionally, for both tasks, depressive symptoms were inversely related to postconflict reaction time adjustments following negative, but not positive, feedback. These findings suggest that subclinical depression is associated with impairments in behavioral adjustments after internal (perceived failure) and external feedback about deficient task performance.