Remapping the cognitive and neural profiles of children who struggle at school

Our understanding of learning difficulties largely comes from children with specific diagnoses or individuals selected from community/clinical samples according to strict inclusion criteria. Applying strict exclusionary criteria overemphasizes within group homogeneity and between group differences, and fails to capture comorbidity. Here, we identify cognitive profiles in a large heterogeneous sample of struggling learners, using unsupervised machine learning in the form of an artificial neural network. Children were referred to the Centre for Attention Learning and Memory (CALM) by health and education professionals, irrespective of diagnosis or comorbidity, for problems in attention, memory, language, or poor school progress (n = 530). Children completed a battery of cognitive and learning assessments, underwent a structural MRI scan, and their parents completed behavior questionnaires. Within the network we could identify four groups of children: (a) children with broad cognitive difficulties, and severe reading, spelling and maths problems; (b) children with age‐typical cognitive abilities and learning profiles; (c) children with working memory problems; and (d) children with phonological difficulties. Despite their contrasting cognitive profiles, the learning profiles for the latter two groups did not differ: both were around 1 SD below age‐expected levels on all learning measures. Importantly a child's cognitive profile was not predicted by diagnosis or referral reason. We also constructed whole‐brain structural connectomes for children from these four groupings (n = 184), alongside an additional group of typically developing children (n = 36), and identified distinct patterns of brain organization for each group. This study represents a novel move toward identifying data‐driven neurocognitive dimensions underlying learning‐related difficulties in a representative sample of poor learners.     

When There Is Not Enough to Go Around: How Black People’s Perceptions of Competition for Black Mates Affects Forced Black Identity Ascriptions of Black/White Multiracial People

Using a resource scarcity framework, the current study investigated whether Black people’s perceptions of competition for Black mates related to ascribing a Black identity onto Black/White Multiracial people. Participants took online questionnaires that assessed competition for Black mates, likelihood of forcing a Black identity onto a self-identified Black/White Multiracial person, essentialism, and contact with Multiracial people. Results indicated that increased perceptions of competition for Black mates was related to increased forced Black identity onto self-identified Black/White Multiracial people, above and beyond levels of essentialism and contact. This relationship was stronger for sexual minorities. The current research supports the proposition that scarcity of resources (i.e., mates) affects ideologies regarding Black/White Multiracial people’s identities.     

Representation of Functions and Total Antisymmetric Relations in Monadic Third Order Logic

Journal of Philosophical Logic - We analyze the representation of binary relations in general, and in particular of functions and of total antisymmetric relations, in monadic third order logic,...     

MOVERS AND SHAKERS: HOW AND WHY WOMEN BECOME AND REMAIN ENGAGED IN COMMUNITY LEADERSHIP

This research examines women's narratives regarding the experiences that lead to becoming, sustaining, and challenging active community leaders. Seventeen women neighborhood leaders, age 28 to 73 years, completed in-depth interviews. Qualitative thematic content analyses identified prominent themes in participants' responses that were subsequently linked to a generativity framework. Analyses revealed that leaders reported circuitous rather than linear paths of emerging community participation and growing up among others who demonstrated an ethos of care in informal as well as formal community practices. Women's initial community engagement was most often in response to invitations to address community needs. Both communal and agentic rewards and challenges to community involvement were identified. Based upon the findings, strategies for promoting and sustaining women's community leadership are identified.     

Symmetry as a Criterion for Comprehension Motivating Quine’s ‘New Foundations’

A common objection to Quine’s set theory “New Foundations” is that it is inadequately motivated because the restriction on comprehension which appears to avert paradox is a syntactical trick. We present a semantic criterion for determining whether a class is a set (a kind of symmetry) which motivates NF. Presented by Melvin Fitting     

Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit

N-Methyl-D-aspartate receptors (NMDARs) mediate certain forms of synaptic plasticity and learning. We used a touchscreen system to assess NR2A subunit knockout mice (KO) for (1) pairwise visual discrimination and reversal learning and (2) acquisition and extinction of an instrumental response requiring no pairwise discrimination. NR2A KO mice exhibited significantly retarded discrimination learning. Performance on reversal was impaired in NR2A KO mice during the learning phase of the task; with no evidence of heightened perseverative responses. Acquisition and extinction of an instrumental behavior requiring no pairwise discrimination was normal in NR2A KO mice. The present findings demonstrate a significant and selective deficit in discrimination learning following loss of NR2A.     

Inducing and modulating intrusive emotional memories: a review of the trauma film paradigm

Highly affect-laden memory intrusions are a feature of several psychological disorders with intrusive images of trauma especially associated with post-traumatic stress disorder (PTSD). The trauma film paradigm provides a prospective experimental tool for investigating analogue peri-traumatic cognitive mechanisms underlying intrusion development. We review several historical papers and some more recent key studies that have used the trauma film paradigm. A heuristic diagram is presented, designed to simplify predictions about analogue peri-traumatic processing and intrusion development, which can also be related to the processing elements of recent cognitive models of PTSD. Results show intrusions can be induced in the laboratory and their frequency amplified/attenuated in line with predictions. Successful manipulations include competing task type (visuospatial vs. verbal) and use of a cognitive coping strategy. Studies show that spontaneous peri-traumatic dissociation also affects intrusion frequency although attempts to manipulate dissociation have failed. It is hoped that further use of this paradigm may lead to prophylactic training for at risk groups and an improved understanding of intrusions across psychopathologies.     

Effects of threat cues on attentional shifting, disengagement and response slowing in anxious individuals

According to cognitive models of anxiety, attentional biases for threat may cause or maintain anxiety states. Previous research using spatial cueing tasks has been interpreted in terms of difficulty in disengaging attention from threat in anxious individuals, as indicated by contrasts of response times (RTs) from threat cue versus neutral cue trials. However, on spatial cueing tasks, differences in RT between threat cue and neutral cue trials may stem from a slowing effect of threat on RT, as well as effects on allocation of visuospatial attention. The present study examined the effects of threat cues on both attentional cueing and response slowing. High and low anxious individuals completed a central cue task, which assessed threat-related response slowing, and a spatial cueing task, which assessed attentional biases for angry, happy and neutral faces. Results indicated that interpretation of the anxiety-related bias for threat depended on whether the effect of response slowing was taken into account. The study illustrates an important problem in using the modified spatial cueing task to assess components of threat-related attentional bias. As this experimental method may reflect both threat-related attentional cueing and response slowing effects, it cannot be assumed to provide pure measures of shift or disengagement components of attention bias.     

Links between rapid ERP responses to fearful faces and conscious awareness

To study links between rapid ERP responses to fearful faces and conscious awareness, a backward‐masking paradigm was employed where fearful or neutral target faces were presented for different durations and were followed by a neutral face mask. Participants had to report target face expression on each trial. When masked faces were clearly visible (200 ms duration), an early frontal positivity, a later more broadly distributed positivity, and a temporo‐occipital negativity were elicited by fearful relative to neutral faces, confirming findings from previous studies with unmasked faces. These emotion‐specific effects were also triggered when masked faces were presented for only 17 ms, but only on trials where fearful faces were successfully detected. When masked faces were shown for 50 ms, a smaller but reliable frontal positivity was also elicited by undetected fearful faces. These results demonstrate that early ERP responses to fearful faces are linked to observers' subjective conscious awareness of such faces, as reflected by their perceptual reports. They suggest that frontal brain regions involved in the construction of conscious representations of facial expression are activated at very short latencies.     

Infants lost in (peripersonal) space?

A significant challenge in developing spatial representations for the control of action is one of multisensory integration. Specifically, we require an ability to efficiently integrate sensory information arriving from multiple modalities pertaining to the relationships between the acting limbs and the nearby external world (i.e. peripersonal space), across changes in body posture and limb position. Evidence concerning the early development of such spatial representations points towards the independent emergence of two distinct mechanisms of multisensory integration. The earlier-developing mechanism achieves spatial correspondence by representing body parts in their typical or default locations, and the later-developing mechanism does so by dynamically remapping the representation of the position of the limbs with respect to external space in response to changes in postural information arriving from proprioception and vision.