Couples therapy: effectiveness of treatment and long‐term follow‐up

Most couples therapy theories are developed and tested in the USA. In this clinical study, we investigated such therapies in a Swedish context. Over 300 couples were enrolled in the study of whom just under half completed the end‐of‐treatment assessment and just over 40 per cent a two‐year follow‐up. At the start, the study group displayed severe problems in marital adjustment, dyadic interactions and psychiatric symptoms. A relatively short treatment was used and 50 per cent of the couples attended less than nine sessions. Outcomes of treatment showed significant improvements in relationship matters, individual mental health and enhanced coping abilities. At long‐term follow‐up, all results remained the same and in some aspects improved for both sexes. This study confirms the effectiveness of such therapies in a Swedish context.     

Sidgwick's Problem

Henry Sidgwick regarded his failure to reconcile the claims of rational egoism with those of utilitarianism to reveal a fundamental contradiction within practical reason. However, the conflict that concerns him arises only in relation to a particular kind of agent. While Sidgwick construes his version of the problem to be a systematic formulation of a conflict that arises within the practical reasoning of ordinary people, it is actually an example of a worst-case scenario that reflects the common philosophical tendency to deal with issues in their most challenging form. But such a transformation of ordinary conflicts between self-interest and morality into an insoluble philosophical problem obscures the nature of the more typical practical conflict.     

Cellular memory in spinal nociceptive circuitry

Besides transmitting and processing, neurons may also store information for prolonged periods of time (e.g. by use-dependent change in synaptic strength). In 1966 long-term potentiation (LTP) of synaptic transmission was discovered in the hippocampus, an area implicated in learning and memory. Recent studies show that similar mechanisms apply to pain pathways, at least in the spinal cord, and may account for some forms of clinical problems like hyperalgesia, allodynia, and deafferentation pain states, such as phantom pain. In this review, we briefly summarize key aspects of synaptic plasticity known from the brain and in the spinal cord. Then we describe and discuss related changes in spinal nociceptive neurons based on results from our own laboratory.     

Perceptual,affective, and cognitive judgments of odors: pleasantness and handedness effects

The present study sought to examine the differential processing of pleasant, neutral, and unpleasant odors. The effects of the nostril stimulated (left or right) and the type of judgment (perceptual, affective, or cognitive) performed on the olfactory stimuli were also studied. To this end, 64 subjects were asked to smell pleasant, neutral, and unpleasant odors under four conditions (detection, intensity, pleasantness, and familiarity tasks). The participants were to perform these tasks as quickly as possible, while response times were recorded. The results showed that (i) unpleasant odors were assessed more rapidly than neutral or pleasant odors, and that this was specifically true (ii) during right nostril stimulation, and (iii) during pleasantness assessment, suggesting possible differential cerebral hemisphere involvement, with a right-side advantage for processing of unpleasant affect in olfaction. A handedness effect on familiarity judgment is also discussed.     

Dimensional analysis of sense of coherence using structural equation modelling

The sense of coherence (SOC) concept has been criticized on conceptual and psychometric grounds. The aim of this study was to develop the concept using structural equation modelling. The short 13‐item version of the SOC questionnaire was used and data were collected from two different samples. Each sample consisted of about 2000 individuals, selected to be representative of the Swedish population. A model with a general factor and two subordinate specific factors yielded a satisfactory solution in both samples. The two factors were labelled Social Comprehension and Commitment and Unpleasant Emotions and Inner Tension respectively. It was concluded that the 13‐item SOC scale could to a certain degree be regarded as a measure of negative affectivity and that the suggested model makes the SOC concept more theoretically coherent. Copyright © 1999 John Wiley & Sons, Ltd.     

Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain

Adenosine receptors in the central nervous system have been implicated in the modulation of different behavioural patterns and cognitive functions although the specific role of A(2A) receptor (A(2A)R) subtype in learning and memory is still unclear. In the present work we establish a novel transgenic rat strain, TGR(NSEhA2A), overexpressing adenosine A(2A)Rs mainly in the cerebral cortex, the hippocampal formation, and the cerebellum. Thereafter, we explore the relevance of this A(2A)Rs overexpression for learning and memory function. Animals were behaviourally assessed in several learning and memory tasks (6-arms radial tunnel maze, T-maze, object recognition, and several Morris water maze paradigms) and other tests for spontaneous motor activity (open field, hexagonal tunnel maze) and anxiety (plus maze) as modification of these behaviours may interfere with the assessment of cognitive function. Neither motor performance and emotional/anxious-like behaviours were altered by overexpression of A(2A)Rs. TGR(NSEhA2A) showed normal hippocampal-dependent learning of spatial reference memory. However, they presented working memory deficits as detected by performance of constant errors in the blind arms of the 6 arm radial tunnel maze, reduced recognition of a novel object and a lack of learning improvement over four trials on the same day which was not observed over consecutive days in a repeated acquisition paradigm in the Morris water maze. Given the interdependence between adenosinic and dopaminergic function, the present results render the novel TGR(NSEhA2A) as a putative animal model for the working memory deficits and cognitive disruptions related to overstimulation of cortical A(2A)Rs or to dopaminergic prefrontal dysfunction as seen in schizophrenic or Parkinson's disease patients.     

Body size estimation in early adolescence: factors associated with perceptual accuracy in a nonclinical sample

This study investigated body size estimation in Norwegian adolescents (aged 12-15; N=406) using a distorting photograph technique. The percentage of over- or underestimation was calculated for pictures of the subject, other persons and a neutral object. The Eating Disorders Inventory for Children (EDI-C) was also completed. Among adolescents at risk of eating problems, girls tended to overestimate their own body size while boys showed a pattern of underestimation, compared to a relatively accurate body perception for low-risk subjects. The groups did not differ in the perception of the neutral object. Important predictors of perceived body size included the size estimation of other children, preoccupation with weight and shape, self-esteem, and emotional instability. The results support the predictive value of body size estimation. Gender differences in judgement bias can be interpreted within present aesthetic ideals and their relation to self perception, body image, and eating problems in adolescence.     

Humor as aggression: effects of motivation on hostility expressed in humor appreciation

In 4 studies, the authors examined the hypothesis that relative to primed autonomy motivation, primed control would increase enjoyment of hostile (compared with nonhostile) humor as assessed by self-reported enjoyment and aversiveness and by nonverbal behavior. Results confirmed the hypothesis. Furthermore, initial state hostility moderated the effect such that high-hostility participants who were primed with control motivation especially enjoyed hostile humor. The 2 final studies showed that the effect was mediated by implicit aggression such that the combination of high initial state hostility and control priming led to implicit aggression, which in turn resulted in hostile humor enjoyment. Results are interpreted in terms of the effects of autonomy versus control motivation on intrapersonal self-regulatory processes, which influence interpersonal functioning.