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The ability to compute probability, previously shown in nonverbal infants, apes, and monkeys, was examined in three experiments with pigeons. After responding to individually presented keys in an operant chamber that delivered reinforcement with varying probabilities, pigeons chose between these keys on probe trials. Pigeons strongly preferred a 75% reinforced key over a 25% reinforced key, even when the total number of reinforcers obtained on each key was equated. When both keys delivered 50% reinforcement, pigeons showed indifference between them, even though three times more reinforcers were obtained on one key than on the other. It is suggested that computation of probability may be common to many classes of animals and may be driven by the need to forage successfully for nutritional food items, mates, and areas with a low density of predators.  相似文献   
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Soluble oligomeric forms of amyloid beta (AβO) are regarded as a main cause of synaptic and cognitive dysfunction in Alzheimer’s disease (AD) and have been a primary target in the development of drug treatments for AD. The present study utilized a mouse model of AD induced by intrahippocampal injection of AβO (10 μM) to investigate the effects of Gami-Chunghyuldan (GCD), a standardized multi-herbal medicinal formula, on the presentation of memory deficits and neurohistological pathogenesis. GCD (10 and 50 mg/kg/day, 5 days, p.o.) improved AβO-induced memory impairment as well as reduced neuronal cell death, astrogliosis, and microgliosis in the hippocampus. In addition, GCD prevented AβO-triggered synaptic disruption and cholinergic fiber loss. These results suggest that GCD may be useful in the prevention and treatment of AD.  相似文献   
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Applied Research in Quality of Life - This study aimed to present normative data of Quality of life (QoL) and to evaluate the relationship between sociodemographic factors, multidimensional QoL and...  相似文献   
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Ho  Wing-Chung 《Human Studies》2008,31(4):383-397
The bone of contention that divides Alfred Schutz and Talcott Parsons in their 1940–1941 debate is that Schutz acknowledges an ontological break between the commonsense and scientific worlds whereas Parsons only considers it “a matter of refinement.” Schutz’s ontological distancing that disconnects the “world of consociates” where social reality is directly experienced in face-to-face contacts, and the “world of contemporaries” where the Other is experienced in terms of “types” has been crucial to social scientists. Implicated in the break is that all intellectual attempts to understand experiences of Others must be based on the “models” constructed in the “world of contemporaries” (or “predecessors”); hence, epistemologically, to grasp the subjective point of view with a here-and-now understanding is an outright impossibility. Based on a Schutzian perspective, the author suggests that the sociologist must objectivize the Thou-orientations involved in his/her analysis in order that s/he can possibility grasp the subjective point of view in objective terms.
Wing-Chung HoEmail:
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Research on cognitive models of depression has identified negative cognitive styles and rumination as risk factors for depression. The present study examined the hypothesis that rumination mediates the effect of negative cognitive styles on depression. Specifically, we evaluated the differential effects of two aspects of rumination, characterized by brooding and reflection, on the relationship between negative cognitive styles and level of depressive symptoms. A total of 115 college students and 38 patients suffering from depressive disorders completed a battery of questionnaires measuring levels of depressive symptoms, brooding, reflection, and negative cognitive styles. The results support the notion that there exist two distinct dimensions of rumination and that, of the two, it is brooding and not reflection that mediates the relationship between negative cognitive styles and depression and contributes to its negative outcomes.  相似文献   
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Body dissatisfaction, its risk factors and association with depressed mood have been well investigated in the West. However, more studies are needed to examine further the relation between body dissatisfaction and depressive symptoms and the factors influencing body dissatisfaction in non-Western cultures. The present study examined in a sample of Hong Kong Chinese adolescents the relation between body dissatisfaction and depressive symptoms, and the relation of maternal appraisal of their adolescent's figure to the adolescent's body dissatisfaction and depressive symptoms. We obtained information from 379 boys and 254 girls about their body dissatisfaction and depressive symptoms. Their mothers provided information about their appraisal of their adolescent's body shape and size compared to ideal. Body dissatisfaction was related to depressive symptoms in girls (B = 2.58, p <.01), but not in boys (B = -0.08, p >.10). Negative maternal appraisal did not have direct effects on adolescents' depressive symptoms (B = 0.14, p =.75), but the association between negative maternal appraisal and body dissatisfaction was significantly stronger in adolescents whose ideal was smaller than they perceived themselves to be (B = 0.32, p <.01) than those whose ideal was larger than their own perception (B = 0.14, p < .01). Our findings suggest that maternal appraisal had indirect effects on mood, acting through adolescents' body dissatisfaction, and that body dissatisfaction may be a sex-specific risk factor for depression. This study points to the need for testing and adapting programs to reduce body dissatisfaction particularly in girls at risk for depression, and to raise mothers' awareness of the link between their negative appraisals and their adolescents' body dissatisfaction and depressive symptoms.  相似文献   
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