Engaging in imagery versus verbal processing of worry: Impact on negative intrusions in high worriers

Chronic, excessive, and uncontrollable worry is the defining characteristic of generalised anxiety disorder. Worry largely consists of verbal thought and it has been postulated that this predominance of verbal thought in worry may contribute to its perseveration. In an investigation of this issue, high worriers were trained to engage in either imagery or verbal processing. Mentation was sampled before and after a five-minute period of worry during which participants engaged in either imagery of the worry topic or verbal processing of the worry topic. Verbal worry resulted in a significant increase in negative intrusions, consistent with previous research. Furthermore, imagery was associated with a decrease in negative intrusions. The results support the theory that the predominantly verbal nature of worry may be responsible for the uncontrollability and maintenance of worry.     

Psychiatric care in Leipzig--10 years' regionalized care in a large city by 3 major clinics

The paper deals with experience gained in the town of Leipzig in the course of the implementation of the regionalized organisation of psychiatric care. The idea behind the organisational structure is that of a complete psychiatric system of treatment, covering hospitalised, partially hospitalised, and out-patient treatment, supported by ancillary services, to provide continued care. The organisational structure has proved effective for basic psychiatric care in a large town.     

Use of pocket computers for self-administration of cognitive tests in the field

A pocket computer is described that can be used by subjects to self-administer cognitive tests in field situations. Two cognitive tests, a vigilance and an encoding task, were developed for this computer and used to test cognitive performance during a 30-day military field exercise.     

Excitatory conditioning of individual Drosophila melanogaster

Testing individual animals from a heterogenic population of Drosophila melanogaster, we demonstrate conditioning of the proboscis extension reflex. The presentation of paired (conditioning) stimuli produced (a) an increase in the average number of conditioned responses over trials, (b) measured differences in performance levels among individual subjects, and (c) a sex difference, with more males conditioned than females, and those that did did so more quickly. The presentation of unpaired (control) stimuli produced significantly lower average levels of acquisition responding and a change in the distribution of individual response patterns. Neither central excitatory state nor sensitization induced by the conditioned or unconditioned stimuli directly affected the conditioned response, whereas unconditioned stimulus preexposure adversely affected performance levels. Presenting the unpaired (extinction) stimuli after conditioning produced less of a decline in responding than did an extinction procedure with removal of the unconditioned stimulus. With the ability to identify individual differences in acquisition and extinction patterns, and given the relatively large number of individuals that can be tested simultaneously on the automated stimulation apparatus, it is now possible to make precise behavioral measurements on samples large enough for the behavior-genetic analysis of D. melanogaster with conditioning as the phenotype.     

Fatigue and Quality of Life in Hepatitis C: Fact or Fiction?

The chronic hepatitis C virus (HCV) has traditionally been impossible to treat. Recently there has been increased attention in the treatment of HCV due to the development of drug treatments (i.e., Interferon and Ribavirin). As clinical attention to the assessment and treatment of HCV has increased, the issue of fatigue has become a central concern. Fatigue is one of the major symptoms reported by those suffering from HCV but it is not clear whether fatigue should be treated as a major symptom that is an important focus on attention or if it is a minor and irrelevant concern. In this paper, we examine the issues of fatigue in HCV in light of the importance of health-related quality of life in HCV. We present evidence to suggest that fatigue is a major issue that warrants clinical attention. We also propose that fatigue be reconceptualized as lassitude and provide an operationalized definition of dysfunctional lassitude, a new clinical construct that may have value as a psychological diagnosis. The purpose of this paper is to provide those interested in psychological issues in HCV, and chronic illnesses for which fatigue is a major symptom, guidelines for future clinical and research efforts.     

Impaired positive inferential bias in social phobia

People with social phobia report anticipatory and retrospective judgments about social situations that appear consistent with a negative interpretative bias. However, it is not at all clear that biased interpretative inferences are made "on-line;" that is, at the time that ambiguous information is first encountered. In a previous study, volunteers who were anxious about interviews were found to lack the positive on-line inferential bias that was characteristic of nonanxious controls but also failed to show a bias favoring threatening inferences (C. R. Hirsch & A. Mathews, 1997). This finding was confirmed in the present study, in which social phobic patients showed no evidence of making on-line emotional inferences, in contrast with socially nonanxious controls who were again clearly biased in favor of positive inferences. The authors concluded that nonanxious individuals are characterized by a benign on-line inferential bias, but that this is impaired in people with social phobia.     

On Rationales for Cognitive Values in the Assessment of Scientific Representations

Cognitive values like simplicity, broad scope, and easy handling are properties of a scientific representation that result from the idealization which is involved in the construction of a representation. These properties may facilitate the application of epistemic values to credibility assessments, which provides a rationale for assigning an auxiliary function to cognitive values. In this paper, I defend a further rationale for cognitive values which consists in the assessment of the usefulness of a representation. Usefulness includes the relevance of a representation regarding the investigation of a given problem and its practicability for the users. This rationale builds on the claim that any evaluation of scientific representations should pursue two aims: providing information about their credibility and providing information about their usefulness. Cognitive values relating to the usefulness of a representation and epistemic values relating to its credibility both perform a first-order function. Cognitive values are abstract, and several values with first-order functions may conflict in their application. Thus, in order for cognitive values to account for the sort of problem that is to be investigated by means of a representation, they need to be appropriately specified and weighed. Comprehensiveness, complexity, high resolution, and easy handling, for instance, may be required in a first-order function for model-based prediction of regional climate impacts but not for explaining how the global climate system works. Specifying and weighing cognitive and epistemic values relative to a given problem is a legitimate second-order function of social values.