LEX I and II: Two databases of surface word forms for psycholinguistic research in Spanish

Two databases of Spanish surface word forms are presented. Surface word forms are words considered as orthographically or phonologically specified without reference to their meaning or syntactic category. The databases are based on the productive written vocabulary of children between the ages of 6 and 10 years. Statistical and structural information is presented concerning surface word-form frequency, consonant-vowel (CV) structure, number of syllables, syllables, syllable CV structure, and subsyllabic units. LEX I was intended to aid in the study of reading processes. Entries were orthographic surface word forms; words were divided in their components following orthographic criteria. LEX II was designed for spoken language research. Accordingly, words were transcribed phonologically and phonological criteria were applied in extracting the internal units. Information about stress location was also provided. Together, LEX I and LEX II represent a useful tool for psycholinguists interested in the study of people acquiring Spanish as a first or foreign language and of Spanish-speaking populations in general.     

Prosodic Awareness Skills and Literacy Acquisition in Spanish

There has been very little research in Spanish on the potential role of prosodic skills in reading and spelling acquisition, which is the subject of the present study. A total of 85 children in 5th year of Primary Education (mean age 10 years and 9 months) performed tests assessing memory, stress awareness, phonological awareness, reading and spelling. In written language tests, errors were classified as phonological (grapheme-to-phoneme conversion rules) or stress-related (placement of the stress mark). Regression analyses showed that, once memory and phonological awareness were controlled, stress awareness partially explained reading and spelling performance as well as error type; however, differences were found between reading and spelling errors. These results show a relationship between prosodic skills--namely stress sensitivity--and the acquisition of reading and spelling skills that seems to be independent of phonological awareness skills.     

Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c

Homer1 belongs to a family of scaffolding proteins that interact with various post-synaptic density proteins including group I metabotropic glutamate receptors (mGluR1/5). Previous research in our laboratory implicates the Homer1c isoform in spatial learning. Homer1 knockout mice (H1-KO) display cognitive impairments, but their synaptic plasticity properties have not been described. Here, we investigated the role of Homer1 in long-term potentiation (LTP) in the hippocampal CA1 region of H1-KO mice in vitro. We found that late-phase LTP elicited by high frequency stimulation (HFS) was impaired, and that the induction and maintenance of theta burst stimulation (TBS) LTP were reduced in H1-KO. To test the hypothesis that Homer1c was sufficient to rescue these LTP deficits, we delivered Homer1c to the hippocampus of H1-KO using recombinant adeno-associated virus (rAAV). We found that rAAV-Homer1c rescued HFS and TBS-LTP in H1-KO animals. Next, we tested whether the LTP rescue by Homer1c was occurring via mGluR1/5. A selective mGluR5 antagonist, but not an mGluR1 antagonist, blocked the Homer1c-induced recovery of late-LTP, suggesting that Homer1c mediates functional effects on plasticity via mGluR5. To investigate the role of Homer1c in spatial learning, we injected rAAV-Homer1c to the hippocampus of H1-KO. We found that rAAV-Homer1c significantly improved H1-KO performance in the Radial Arm Water Maze. These results point to a significant role for Homer1c in synaptic plasticity and learning.     

The Princess and the Penis: A Post Postmodern Queer-y Tale

This paper explores whether postmodern gender theory can fully account for how a “cis” gender (gender and biology match) therapist works with a “trans” gender patient in a relational way. Inspiring contemporary queer theory exists courtesy of experts in the field, but how does a nongender expert deal with the complicated enactments that occur when patient transitions her gender from female to male and then decides to become pregnant? It is suggested that this case may more accurately represent an example of a post-postmodern analysis, in that it holds the dialectic of constructed gender within the realities of a social system that remains deeply gender binaried.     

Emotion-specific modulation of early visual perception

Exposure to fearful facial expressions enhances vision at low spatial-frequencies and impairs vision at high spatial-frequencies. This perceptual trade-off is thought to be a consequence of a fear-related activation of the magnocellular visual pathway to the amygdala. In this study we examined the generality of the effect of emotion on low-level visual perception by assessing participants' orientation sensitivity to low and high spatial-frequency targets following exposure to disgust, fear, and neutral facial expressions. The results revealed that exposure to fear and disgust expressions have opposing effects on early vision: fearful expressions enhanced low spatial-frequency vision and impaired high spatial-frequency vision, while disgust expressions, like neutral expressions, impaired low spatial-frequency vision and enhanced high spatial-frequency vision. Thus we show the effect of exposure to fear on visual perception is not a general emotional effect, but rather one that may that depend on amygdala activation, or one that may be specific to fear.     

Between Dolev and Dummett: Some Comments on ‘Antirealism,Presentism and Bivalence’

Abstract

It is well known that, according to some, philosophical reflection on zombies (i.e. bodies without minds) poses a problem for physicalism. But what about ghosts, i.e., minds without bodies? Does philosophical reflection on them pose a problem for physicalism? Descartes, of course, thought so, and lately rumours have been surfacing that has was right after all, that ghosts pose a problem for both a priori and a posteriori physicalism, and for any kind of physicalism in between. This paper argues that physicalists have nothing to fear from ghosts, since the central consideration employed to motivate ghostly arguments against physicalism – i.e. that ghosts are conceivable – is false: ghosts aren’t conceivable.