Hypothalamo-Pituitary-Adrenocortical Regulation Following Lesions of the Central Nucleus of the Amygdala

Previous reports indicate that the central nucleus of the amygdala (CeA) stimulates adrenocorticotropin and corticosterone secretion, suggesting a role for this region in central hypothalamo-pituitary-adrenocortical (HPA) stress regulation. To evaluate this hypothesis, this study assessed the impact of CeA lesion on the response of hypophysiotrophic paraventricular nucleus (PVN) neurons to acute restraint and chronic unpredictable stress exposure. In contrast to previous reports, CeA lesions did not affect corticosterone or ACTH secretion induced by acute stress. Acute restraint increased PVN corticotropin releasing hormone (CRH) mRNA expression, increased the number of parvocellular PVN neurons expressing the co-secretagogue arginine vasopressin (AVP), and induced cFOS mRNA expression in the parvocellular PVN. However, there was no additional effect of CeA lesion on any measure of PVN activation. Chronic unpredictable stress exposure induced long-term activation of the HPA axis, noted by thymic involution, adrenal hypertrophy and increased PVN CRH mRNA expression. Stress-induced changes in thymus and adrenal weights were not affected by CeA lesion. Further, CeA lesion rats did not differ from controls in post-stress CRH mRNA expression. However, basal CRH mRNA expression was increased in the PVN of CeA rats, suggesting that the CeA plays a role in long-term inhibition of the PVN. The results of these studies are not consistent with the hypothesis that the CeA is necessary for stress-induced pituitary-adrenocortical activation. Rather, this region may play a stressor-specific modulatory role in regulation of HPA function.     

Gender-role conflict and gender-role orientation in a sample of gay men

This exploratory study was designed to examine the relationship between gender role dimensions derived from the Bem Sex-Role Inventory (BSRI) and the 4 dimensions of gender role conflict represented on the Gender Role Conflict Scale (GRCS) using a sample (N = 400) composed of exclusively gay men. Results from regression of 3 BSRI scores (femininity, social masculinity, personal masculinity) on the 4 subscale scores of the GRCS indicated that gender role conflict was most strongly and positively associated with the negative aspect of masculinity (social masculinity), accounting for about 11% of variability in social masculinity scores. In particular, the success-power-competition dimension of the GRCS was the major predictor of social masculinity in gay men. Gender role conflict was also strongly but negatively associated with femininity, accounting for approximately 10% of the variance in femininity scores among the men in the sample. Implications and recommendations for further studies are discussed.     

Imageability effects in word naming: an individual differences analysis.

The present research was designed to extend research by Strain, Patterson, and Seidenberg (1995) who found that imageability facilitates naming of low-frequency irregular words. Experiment 1 shows that the impact of imageability on word naming varies with phonological coding skill. In Experiment 2, the effect of imageability on naming low-frequency irregular words was shown to occur across an extended set of items. Together, the present findings support the notion that semantics may play a role in phonological coding when the mappings between orthography and phonology are weak.     

Directed attention and perception of temporal order.

The present research examined the effects of directed attention on speed of information transmission in the visual system. Ss judged the temporal order of 2 stimuli while directing attention toward 1 of the stimuli or away from both stimuli. Perception of temporal order was influenced by directed attention: Given equal onset times, the attended stimulus appeared to occur before the unattended stimulus. Direction of attention also influenced the perception of simultaneity. The findings support the notion that attention affects the speed of transmission of information in the visual system. To account for the pattern of temporal order and simultaneity judgments, a model is proposed in which the temporal profile of visual responses is affected by directed attention.     

Attentional resource demands of visual word recognition in naming and lexical decisions.

Attentional demands of lexical access were assessed with dual-task methodology. Subjects performed an auditory probe task alone (single-task) or combined (dual-task) with either a lexical decision or a naming task. In Experiment 1, probe performance showed a decrement from single- to dual-task conditions during recognition of words in both lexical decision and naming tasks. In addition, decrements in probe performance were larger during processing of low-frequency compared with high-frequency words in both of the word recognition tasks. Experiment 2 showed that the time course of frequency-sensitive demands was similar across lexical decision and naming tasks and that attention is required early in the word recognition sequence. The results support the assumption that lexical access is both frequency sensitive and attention demanding.     

Naming cAsE aLtErNaTeD words

A dual-route approach was used as an initial framework to examine the relation between presentation format and lexical processing in a naming task. In Experiments 1 and 3, words were presented in lowercase versus case-alternated format. Presentation format interacted with word frequency and regularity: For irregular words (e.g., pint), case alternation was additive with frequency, whereas for regular words (e.g., mint), case alternation and frequency interacted. Experiment 2 dissociated the locus of case-alternation effects from those of stimulus intensity. Stimulus intensity was additive with frequency and regularity, suggesting that whereas stimulus intensity affects encoding, case alternation affects lexical processing at a postencoding stage in the word recognition system. It was concluded that a dual-route approach provides a suggestive but incomplete account of how case alternation influences lexical processing. As an alternative to a dual-route approach, we show that the present results can be addressed and successfully simulated using an implemented version of Norris's (1994) multilevel model.