Electrophysiological evidence for cognitive control during conflict processing in visual spatial attention

Event-related potentials were measured to investigate the role of visual spatial attention mechanisms in conflict processing. We suggested that a more difficult target selection leads to stronger attentional top-down control, thereby reducing the effects of arising conflicts. This hypothesis was tested by varying the selection difficulty in a location negative priming (NP) paradigm. The difficult task resulted in prolonged responses as compared to the easy task. A behavioral NP effect was only evident in the easy task. Psychophysiologically the easy task was associated with reduced parietal N1, enhanced frontocentral N2 and N2pc components and a prolonged P3 latency for the conflict as compared to the control condition. The N2pc effect was also obvious in the difficult task. Additionally frontocentral N2 amplitudes increased and latencies of N2pc and P3 were delayed compared to the easy task. The differences at frontocentral and parietal electrodes are consistent with previous studies ascribing activity in the prefrontal and parietal cortex as the source of top-down attentional control. Thus, we propose that stronger cognitive control is involved in the difficult task, resulting in a reduced behavioral NP conflict.     

Multimodal encoding in a simplified model of intracellular calcium signaling

Many cells use calcium signaling to carry information from the extracellular side of the plasma membrane to targets in their interior. Since virtually all cells employ a network of biochemical reactions for Ca²⁺ signaling, much effort has been devoted to understand the functional role of Ca²⁺ responses and to decipher how their complex dynamics is regulated by the biochemical network of Ca²⁺-related signal transduction pathways. Experimental observations show that Ca²⁺ signals in response to external stimuli encode information via frequency modulation (FM) or alternatively via amplitude modulation (AM). Although minimal models can capture separately both types of dynamics, they fail to exhibit different and more advanced encoding modes. By arguments of bifurcation theory, we propose instead that under some biophysical conditions more complex modes of information encoding can also be manifested by minimal models. We consider the minimal model of Li and Rinzel and show that information encoding can occur by AM of Ca²⁺ oscillations, by FM or by both modes (AFM). Our work is motivated by calcium signaling in astrocytes, the predominant type of cortical glial cells that is nowadays recognized to play a crucial role in the regulation of neuronal activity and information processing of the brain. We explain that our results can be crucial for a better understanding of synaptic information transfer. Furthermore, our results might also be important for better insight on other examples of physiological processes regulated by Ca²⁺ signaling.     

Multimodal encoding in a simplified model of intracellular calcium signaling

Many cells use calcium signaling to carry information from the extracellular side of the plasma membrane to targets in their interior. Since virtually all cells employ a network of biochemical reactions for Ca²⁺ signaling, much effort has been devoted to understand the functional role of Ca²⁺ responses and to decipher how their complex dynamics is regulated by the biochemical network of Ca²⁺-related signal transduction pathways. Experimental observations show that Ca²⁺ signals in response to external stimuli encode information via frequency modulation (FM) or alternatively via amplitude modulation (AM). Although minimal models can capture separately both types of dynamics, they fail to exhibit different and more advanced encoding modes. By arguments of bifurcation theory, we propose instead that under some biophysical conditions more complex modes of information encoding can also be manifested by minimal models. We consider the minimal model of Li and Rinzel and show that information encoding can occur by AM of Ca²⁺ oscillations, by FM or by both modes (AFM). Our work is motivated by calcium signaling in astrocytes, the predominant type of cortical glial cells that is nowadays recognized to play a crucial role in the regulation of neuronal activity and information processing of the brain. We explain that our results can be crucial for a better understanding of synaptic information transfer. Furthermore, our results might also be important for better insight on other examples of physiological processes regulated by Ca²⁺ signaling.     

Nonlinear visuomotor transformations: locus and modularity

Participants in two experiments moved a mouse-like device to the right to move a cursor on a computer screen to a target position. The cursor was invisible during motion but reappeared at the end of each movement. The relationship between the amplitudes of the cursor movement and the mouse movement was exponential in Experiment 1 and logarithmic in Experiment 2 for two groups of participants, while it was linear for the control groups in both experiments. The results of both experiments indicate that participants adjusted well to the external transformation by developing an internal model that approximated the inverse of the external transformation. We introduce a method to determine the locus of the internal model. It indicates that the internal model works at a processing level that either preceded specification of movement amplitude, or had become part of movement amplitude specification. Limited awareness of the nonlinear mouse-cursor relationship and the fact that a working-memory task had little effect on performance suggest that the internal model is modular and not dependent on high-level cognitive processes.     

A framework for the unification of the behavioral sciences

The various behavioral disciplines model human behavior in distinct and incompatible ways. Yet, recent theoretical and empirical developments have created the conditions for rendering coherent the areas of overlap of the various behavioral disciplines. The analytical tools deployed in this task incorporate core principles from several behavioral disciplines. The proposed framework recognizes evolutionary theory, covering both genetic and cultural evolution, as the integrating principle of behavioral science. Moreover, if decision theory and game theory are broadened to encompass other-regarding preferences, they become capable of modeling all aspects of decision making, including those normally considered "psychological," "sociological," or "anthropological." The mind as a decision-making organ then becomes the organizing principle of psychology.     

结构方程模型检验：拟合指数与卡方准则

讨论了Hu和Bentler（1998,1999）推荐的检验结构方程模型的7个拟合指数准则,对这7个指数的历史、特点和表现做了比较详细的述评。指出了他们基于这7个指数的单指数准则和2-指数准则的不足之处。提出了超低显著性水平下的卡方准则,并部分重复他们的模拟例子,将卡方准则与这7个指数准则比较,结果说明新的卡方准则优于其中的6个,与另一个相当。最后简要说明了应当如何检视拟合指数进行模型检验和模型比较。     

Religious Fundamentalism and Gender Differences

The role of religious fundamentalism and its relationship to shame and guilt was evaluated in 107 students who attend a church-sponsored university. A number of personality measures were given and gender differences were analyzed. The role of externalization was similar for males in this sample to that of earlier studies. However, it was found that females showed positive correlations between externalization and both shame and guilt. For females, more fundamentalistic religious training may help to contribute to an external orientation at the expense of identifying with a personal religion, and appropriate guilt.