Information processing in chronic pain disorder: A preliminary analysis

Researchers have alternately suggested selective attention, impaired stimulus filtering, and affective language deficiency models as accounting for multiple somatic complaints in persons with chronic pain disorder. The purpose of the present study was to establish the comparative usefulness of these three models for explaining somatic focus in a chronic pain population. Nine chronic pain patients evidencing high somatic focus (somatizing chronic pain patients), 10 chronic pain patients evidencing low somatic focus (nonsomatizing chronic pain patients), and 10 healthy control subjects were administered a computerized version of the emotional Stroop test as a test of these models. A total of 105 pain-, depression-, and neutral-content words were used as Stroop test stimuli. Stroop test color-naming response latencies were submitted to a two-way Group × Word Type mixed-model ANOVA, with Word Type as the repeated measure. Results reveal that neither the selective attention model nor the affective language deficiency model adequately explain Stroop test performance in somatizing chronic pain patients. Findings provide tentative support for the impaired stimulus filtering model, with somatizing chronic pain patients evidencing similar Stroop test response delays across all words. These results suggest that chronic pain sufferers misinterpret bodily sensations. Findings are discussed in terms of a bilevel approach for treatment of somatizing chronic pain patients that would include assisting the patient in accurate appraisal and interpretation of physical symptoms.     

Central inhibitory dysfunctions: mechanisms and clinical implications

Injury to the central or peripheral nervous system is often associated with persistent pain. After ischemic injury to the spinal cord, rats develop severe mechanical allodynia-like symptoms, expressed as a pain-like response to innocuous stimuli. In its short-lasting phase the allodynia can be relieved with the gamma-aminobutyric acid (GABA)-B receptor agonist baclofen, which also reverses the hyperexcitability of dorsal horn interneurons to mechanical stimuli. Furthermore, there is a reduction in GABA immunoreactivity in the dorsal horn of allodynic rats. Clinical neuropathic pain of peripheral and central origin often cannot be relieved by opiates at doses that do not cause side effects. The loss of sensitivity to opiates may be associated with the up-regulation of endogenous antiopioid substances, such as the neuropeptide cholecystokinin (CCK). CCK and its receptor (CCK-R) protein is normally not detectable in rat dorsal root ganglion cells. After peripheral nerve section, both CCK and CCK-R are up-regulated in the dorsal root ganglia. Furthermore, CI 988, an antagonist of the CCK-B receptor, chronically coadministered with morphine, reduces autotomy, a behavior that may be a sign of neuropathic pain following peripheral nerve section. Thus, opiate insensitivity may be due to the release of CCK from injured primary afferents. Similarly, in the chronic phase of the spinal ischemic model of central pain, the allodynia-like symptom is not relieved by systemic morphine, but is significantly reversed by the CCK-B antagonist. Consequently, up-regulation of CCK and CCK-R in the CNS may also underlie opiate drug insensitivity following CNS injury. Thus, dysfunction of central inhibition involving GABA and endogenous opioids may be a factor underlying the development of sensory abnormalities and/or pain following injury to neural tissue.     

Some test correlates of high level creativity in architects

The Rorschachs of 40 eminent architects, intensively studied at the Institute of Personality Assessment and Research (California) in 1959, were analyzed in terms of styles of responding (cognitive-affective controls). Level of creative talent (assessed by a competent jury of peers) was not related to styles of responding but the Rorschach data give us reason to believe that subjects with high degrees of repressive control may be more limited in creative expression. Qualitative analysis of Rorschach content suggests drive level is related to creative excellence.     

Cognitive and life stress predictors of relapse in remitted unipolar depressed patients: test of the congruency hypothesis.

Remitted depressed subjects (N = 59) were followed longitudinally to determine whether dependent or self-critical persons are more vulnerable to relapse after exposure to life events that have a bearing on interpersonal or achievement concerns. Regression analyses indicated that congruency effects, as measured by the occurrence of achievement-related adversity in the lives of self-critical subjects, accounted for a significant increment in relapse variance over each variable entered singly. When data from the 2 months just before relapse were analyzed, some evidence of congruency effects in dependent subjects experiencing interpersonal-related adversity was obtained. These findings highlight the dimensional qualities of life even impact and call for greater differentiation in modeling the activation of a diathesis and precipitation of depression after life stress.     

Depression,self-focus,and social interaction

The accuracy of depressed and nondepressed subjects' perceptions of their own and a social interactional partner's performance was investigated. Twenty depressed and twenty nondepressed college students participated in dyadic interactions and then rated their own and their partner's social behavior. The interactions were also rated by objective coders. Depressed subjects were differentiated from nondepressed subjects on several measures by both the coders and the subjects. Depressed subjects' self-ratings were correlated with the coders' ratings more often than were the nondepressives' ratings, suggesting depressives provided more accurate self-observations. Contrary to prediction, depressives were also more accurate in judging their partner's behavior. Depressives experienced heightened levels of self-focused attention, but this attentional focus did not mediate the relationship between depression level and self-accuracy. Finally, an analysis of the verbal statements suggests that performance differences between depressives and nondepressives may be a function of the quantity, rather than the quality, of the verbal production.     

Affiliative vocalizations in infant rhesus macaques (Macaca mulatta).

In Experiment 1, infant rhesus monkeys (Macaca mulatta) were separated and then reunited with mothers, united with a male, or placed in an empty cage. Infants girned more when with mothers or the male than when alone. Girns declined over time when infants were united with the male. Coo rates were high when the infant was alone or with the male. Shrieks, barks, and fear-related behavior were higher with the male. In Experiment 2 the vocalizations of infants were examined during separation when alone or when mothers or a male were in the same room. Infants cooed more when mothers or a male were present. Cooing increased over time, with a greater increase in the mothers' presence. Girns were given to both mothers and males, but more were given to mothers. Coos and girns are both affiliative vocalizations but are differentially modulated as infants cease cooing when they receive contact comfort.     

Primary process in creative persons

The major hypothesis that quantity, quality, and control of primary process contents would be different in two groups of artists as a function of age and experience were tested by means of the Rorschach test. The Holt system of scoring was employed. A group of art students, mean age 21.7, and a group of renowned, mature artists, mean age 41.7, were compared. It was found that while quantity of primary process did not differ, the quality, density, defense demand, efficiency of defenses and controls, form level and REGO significantly differentiated experienced from inexperienced artists.     

The cybernetic approach to the treatment of neurotic disorders

This work is an attempt at a cybernetic analysis of the process of treatment of neurotic disorders. This approach is based on the consideration of a patient as an object of control. Assuming that the neurosis is an expression of some imbalance in an organism, the process of treatment is reduced to the exertion of influence on the system thrown out of balance (i.e., the patient) so that its homeostasis with the environment is restored. Thus the treatment of neurotic disorders consists of the use of negative feedback, both internal (those within the patients organism) and external (those within the system created by the interaction of patient and environment).