Sexual experience and preference for males or females in the female rat

The influence of sexual experience on preference behavior was investigated in adult female rats. In the first experiment, preference behavior for sexually active males versus estrous females was investigated in female rats who were experienced with mounting behavior. Preference of these mount experienced females was compared to preference of females who were naive in this respect. Mount experience with estrous females induced a female-directed preference in ovariectomized female rats, irrespective of whether the females were treated with OIL or with testosterone-propionate (500 micrograms TP, injected once 48 h prior to testing). Sexually naive, OIL-treated females did not show a preference for males or females, but TP induced a preference for a male. Individual differences in mount frequency were not correlated with preference behavior. In the second experiment, the influence of experience with feminine sexual responses on preference behavior was investigated. OIL-treated and TP-treated females oriented equally toward males and females when they had been given the opportunity to copulate with males prior to the preference tests. The results strongly suggest that prior sexual experience is an important determinant of preference behavior. The female's behavior during sexual interactions was, however, not predictive of later preference.     

Observed behaviors during clinical interviews predict improvement in depression

A considerable percentage of depressed patients do not respond to antidepressive treatment. Early indicators of prognosis are needed. The aims of this study are to examine (a) whether the interpersonal behavior of patients and psychiatrist, as assessed by means of direct observation of behavior during a baseline clinical interview, might have predictive value with respect to therapeutic outcome and (b) which predictive potency measures of psychomotor activation, as assessed by less refined methods, such as global clinical judgment, might have. In the analysis used, speech-pause behavior was taken as the basic structure of the interaction. The relations of other behaviors such as looking and hand and head movement with this structure were determined. Evidence is presented that in a group of 31 depressives, improvement after a period of 10 weeks was related to observed behaviors during a baseline interview. The behaviors of the patients are interpreted as relational or nonrelational. The relational behaviors (i.e., looking yesnodding, gesturing) occur less in patients who will improve, whereas the nonrelational behaviors (i.e., intensive body touching, head movements) occur more in these patients. The nonrelational behaviors are presumed to be indicative of the state of arousal. The predictive potency of these variables could not be explained by their relationship with the baseline severity of depression, which in itself also predicted improvement. Moreover, global clinical assessment of psychomotor activation (i.e., retardation and agitation) could not be related to outcome.     

Cognitive determinants of lactate-induced anxiety

The effects of lactate infusion on subjective mood change were studied in two differently instructed groups, in a double-blind, placebo-controlled, cross-over study. Ss who were told that infusions would produce anxiety reported a significant change in the expected direction after lactate but not after glucose. Ss who were told that infusions would produce a state of pleasant excitement showed no change after either infusion. The possible role of cognitive parameters in experimentally-induced anxiety is discussed.     

On the relation between indistinguishability of identical particles and (anti)symmetry of the wave function in quantum mechanics

Two different concepts of distinguishability are often mixed up in attempts to derive in quantum mechanics the (anti)symmetry of the wave function from indistinguishability of identical particles. Some of these attempts are analyzed and shown to be defective. It is argued that, although identical particles should be considered as observationally indistinguishable in (anti)symmetric states, they may be considered to be conceptually distinguishable. These two notions of (in)distinguishability have quite different physical origins, the former one being related to observations while the latter has to do with the preparation of the system.     

Substance P facilitation of memory: effects in an appetitively motivated learning task

Food deprived, heterogeneous strain (HS/IBG) mice were trained on two different discrimination tasks for food reinforcement. In one experiment animals were trained to make spatial discriminations in a T maze. Immediately after training they were given subcutaneous injections of either substance P (1 ng/g) or vehicle. Twenty-four hours later the animals were given reversal training in the same maze. The results showed that substance P-treated animals took significantly longer to acquire the reversal habit than did control mice. In a second experiment, animals were trained to make visual discriminations in a T maze. Immediately after reaching acquisition criterion animals were injected with either substance P (1 ng/g) or vehicle. Different groups of mice were retrained on the same task either 1, 2, 3, or 7 days after original learning. Savings scores were calculated and, at every interval, substance P-treated mice retained the task better than control animals. One interpretation of these data is that substance P-treated mice remembered the original task significantly better than vehicle-injected control animals.     

Evidence that fixation digits can contribute to visual field asymmetries in lateralized tachistoscopic tasks

Fixation point digits have been widely used in tachistoscopic laterality studies as a simple and convenient means of ensuring unihemispheric projection of stimulus materials to the hemispheres. Previous findings demonstrate that fixation digits do not influence asymmetries in recognition accuracy studies with adult Ss. Present results, comparing four conditions differing in their use of fixation digits, show that in the naming latency paradigm the requirement to remember and report fixation control digits significantly augments RVF superiority. Implications for other latency tasks are discussed.     

Some evidence for correlated separate activation in a simple letter-detection task

This study investigates the separate activation versus coactivation issue for redundant targets in a simple letter-detection paradigm with latency as the dependent variable. The results of a one-response visual-search task are reported. Since, on single-target trials, only the target was presented and no accompanying noise element, no “distraction decrement” caused by irrelevant noise elements (Grice et al., 1984) was to be expected. The data obtained showed a clear redundantsignal effect. Subsequent detailed analysis of the latency data using Miller’s (1982) procedure indicated that the results were consistent with a separate activation model and failed to provide convincing evidence in favor of coactivation models. A further analysis of the data indicated that, in the present study, the separate channels were negatively correlated for a range of fast RTs and positively correlated for intermediate and larger RTs. No evidence in favor of Grice et al.’s (1984) distraction-decrement hypothesis was found. The conclusions of this study are that (1) a separate activation model summarizes the essential features of information processing in this simple visual search task, and (2) no convincing evidence in favor of coactivation in visual search tasks has been reported in the literature up to now.