The anthropological tradition in the philosophy of medicine

The tradition of anthropological medicine in philosophy of medicine is analyzed in relation to the earlier interest in epistemological issues in medicine around the turn of the century as well as to the current interest in medical ethics. It is argued that there is a continuity between epistemological, anthropological and ethical approaches in philosophy of medicine. Three basic ideas of anthropologically-oriented medicine are discussed: the rejection of Cartesian dualism, the notion of medicine as science of the human person, and the necessity of a comprehensive understanding of disease. Next, it is discussed why the anthropological movement has been superseded by the increasing interest in medical ethics. It is concluded that the present-day moral issues cannot be interpreted and resolved without clarification of the underlying anthropological images.     

Techniques for rotating two or more loading matrices to optimal agreement and simple structure: A comparison and some technical details

Matrices of factor loadings are often rotated to simple structure. When more than one loading matrix is available for the same variables, the loading matrices can be compared after rotating them all (separately) to simple structure. An alternative procedure is to rotate them to optimal agreement, and then compare them. In the present paper techniques are described that combine these two procedures. Specifically, five techniques that combine the ideals of rotation to optimal agreement and rotation to simple structure are compared on the basis of contrived and empirical data. For the contrived data, it is assessed to what extent the rotations recover the underlying common structure. For both the contrived and the empirical data it is studied to what extent the techniques give well matching rotated matrices, to what extent these have a simple structure, and to what extent the most prominent parts of the different loading matrices agree. It was found that the simple procedure of combining a Generalized Procrustes Analysis (GPA) with Varimax on the mean of the matched loading matrices performs very well on all criteria, and, for most purposes, offers an attractive compromise of rotation to agreement and simple structure. In addition to this comparison, some technical improvements are proposed for Bloxom's rotation to simple structure and maximum similarity.This research has been made possible by a fellowship from the Royal Netherlands Academy of Arts and Sciences to the author. The author is obliged to René van der Heijden for assistance in programming the procedures in the simulation study reported in this paper, and to Jos ten Berge, three anonymous reviewers and an associate editor for helpful comments on an earlier version of this paper.     

Three-mode orthomax rotation

Factor analysis and principal components analysis (PCA) are often followed by an orthomax rotation to rotate a loading matrix to simple structure. The simple structure is usually defined in terms of the simplicity of the columns of the loading matrix. In Three-mode PCA, rotational freedom of the so called core (a three-way array relating components for the three different modes) can be used similarly to find a simple structure of the core. Simple structure of the core can be defined with respect to all three modes simultaneously, possibly with different emphases on the different modes. The present paper provides a fully flexible approach for orthomax rotation of the core to simple structure with respect to three modes simultaneously. Computationally, this approach relies on repeated (two-way) orthomax applied to supermatrices containing the frontal, lateral or horizontal slabs, respectively. The procedure is illustrated by means of a number of exemplary analyses. As a by-product, application of the Three-mode Orthomax procedures to two-way arrays is shown to reveal interesting relations with and interpretations of existing two-way simple structure rotation techniques.This research has been made possible by a fellowship from the Royal Netherlands Academy of Arts and Sciences to the author. The author is obliged to Jos ten Berge and two anonymous reviewers for useful comments on an earlier version of this paper.     

Explicit candecomp/parafac solutions for a contrived 2 × 2 × 2 array of rank three

Kruskal, Harshman and Lundy have contrived a special 2 × 2 × 2 array to examine formal properties of degenerate Candecomp/Parafac solutions. It is shown that for this array the Candecomp/Parafac loss has an infimum of 1. In addition, the array will be used to challenge the tradition of fitting Indscal and related models by means of the Candecomp/Parafac process.     

Medicine and the Cartesian image of man

The contemporary philosophy of medicine may be characterized as a continuous struggle with the Cartesian heritage, in order to reach a more satisfying image of man. This paper outlines the influence of Cartesian dualism on the foundations of medicine. The notion of a real distinction between the mental and physical, particularly the mechanistic conception of the human body, made possible the development of the natural sciences as well as scientific medicine, not hampered any longer by the risk of colliding with religion or Church. The Cartesian machine model of man immediately appealed to seventeenth century physicians: Dutch Cartesians (Regius, Craanen) and followers of the iatrophysical school (Santorio, Borelli). Dichotomizing between mind and body, subject and object, self and world, self and other, knower and knowledge is constitutive for modern medicine conceiving itself as a natural science.     

An alternating least squares algorithm for fitting the two- and three-way dedicom model and the idioscal model

The DEDICOM model is a model for representing asymmetric relations among a set of objects by means of a set of coordinates for the objects on a limited number of dimensions. The present paper offers an alternating least squares algorithm for fitting the DEDICOM model. The model can be generalized to represent any number of sets of relations among the same set of objects. An algorithm for fitting this three-way DEDICOM model is provided as well. Based on the algorithm for the three-way DEDICOM model an algorithm is developed for fitting the IDIOSCAL model in the least squares sense.The author is obliged to Jos ten Berge and Richard Harshman.     

Convergence properties of an iterative procedure of ipsatizing and standardizing a data matrix,with applications to parafac/candecomp preprocessing

Centering a matrix row-wise and rescaling it column-wise to a unit sum of squares requires an iterative procedure. It is shown that this procedure converges to a stable solution. This solution need not be centered row-wise if the limiting point of the interations is a matrix of rank one. The results of the present paper bear directly on several types of preprocessing methods in Parafac/Candecomp.     

Fitting the off-diagonal dedicom model in the least-squares sense by a generalization of the harman and jones minres procedure of factor analysis

Harshman's DEDICOM model providesa framework for analyzing square but asymmetric materices of directional relationships amongn objects or persons in terms of a small number of components. One version of DEDICOM ignores the diagonal entries of the matrices. A straight-forward computational solution for this model is offered in the present paper. The solution can be interpreted as a generalized Minres procedure suitable for handing asymmetric matrices.     

Reciprocity: Choice shift in a social trap

In the present study it was investigated if choice behaviour in a social trap situation was affected by feedback about the choice of others. On top of the social trap reward structure investigated by Schroeder, Jensen, Reed, Sullivan and Schwab (1983) a bonus was added. In the individual bonus condition subjects were promised an unspecified bonus if they would obtain more points than any other group member of one's group. In the group bonus condition subjects would obtain a bonus if the own group acquired more points than the other group. As expected, in the group bonus condition one took fewer points than in the individual bonus condition. As suggested by the reciprocity explanation of choice behaviour (Liebrand, Wilke, Vogel and Wolters 1986; Liebrand, Jansen and Rijken 1986) it appeared that first choice corresponded strongly with one's expectations about the choices of others. Before the second choice and also before the third choice one received purported feedback about the choices of other members of one's group. In the conserving condition one learned that all others made a conserving choice, whereas in the consuming condition one learned that all others made a consuming choice. According to the reciprocity explanation it was found that when choice behaviour was in agreement with own previous expectations and previous choice, no choice change did occur. Shifts took place in conditions in which own previous expectations about the choices of others and own choice were disconfirmed by information about choices of others.     

Individual risk taking for self and others

In this experimental study, individual risk taking for self and others was observed for three experimental situations (the choice dilemma situations of Kogan and Wallach, 1964, the Pruitt and Teger gambling situation, 1969, and a simple one-trial gamble game). The results of the present study suggest that one takes as much risk for oneself as for somebody else. An attempt was made to determine to what degree the results could be explained by properties of the experimental situations.