The LMPCA program: A graphical user interface for fitting the linked-mode PARAFAC-PCA model to coupled real-valued data

In behavioral research, PARAFAC analysis, a three-mode generalization of standard principal component analysis (PCA), is often used to disclose the structure of three-way three-mode data. To get insight into the underlying mechanisms, one often wants to relate the component matrices resulting from such a PARAFAC analysis to external (two-way two-mode) information, regarding one of the modes of the three-way data. To this end, linked-mode PARAFAC-PCA analysis can be used, in which the three-way and the two-way data set, which have one mode in common, are simultaneously analyzed. More specifically, a PARAFAC and a PCA model are fitted to the three-way and the two-way data, respectively, restricting the component matrix for the common mode to be equal in both models. Until now, however, no software program has been publicly available to perform such an analysis. Therefore, in this article, the LMPCA program, a free and easy-to-use MATLAB graphical user interface, is presented to perform a linked-mode PARAFAC-PCA analysis. The LMPCA software can be obtained from the authors at http://ppw.kuleuven.be/okp/software/LMPCA. For users who do not have access to MATLAB, a stand-alone version is provided.     

Playing God in Frankenstein’s Footsteps: Synthetic Biology and the Meaning of Life

The emergent new science of synthetic biology is challenging entrenched distinctions between, amongst others, life and non-life, the natural and the artificial, the evolved and the designed, and even the material and the informational. Whenever such culturally sanctioned boundaries are breached, researchers are inevitably accused of playing God or treading in Frankenstein’s footsteps. Bioethicists, theologians and editors of scientific journals feel obliged to provide an authoritative answer to the ambiguous question of the ‘meaning’ of life, both as a scientific definition and as an explication with wider existential connotations. This article analyses the arguments mooted in the emerging societal debates on synthetic biology and the way its practitioners respond to criticism, mostly by assuming a defiant posture or professing humility. It explores the relationship between the ‘playing God’ theme and the Frankenstein motif and examines the doctrinal status of the ‘playing God’ argument. One particularly interesting finding is that liberal theologians generally deny the religious character of the ‘playing God’ argument—a response which fits in with the curious fact that this argument is used mainly by secular organizations. Synthetic biology, it is therefore maintained, does not offend so much the God of the Bible as a deified Nature. While syntheses of artificial life forms cause some vague uneasiness that life may lose its special meaning, most concerns turn out to be narrowly anthropocentric. As long as synthetic biology creates only new microbial life and does not directly affect human life, it will in all likelihood be considered acceptable.     

Further Evidence for Reliability and Validity of the Triarchic Psychopathy Measure in a Forensic Sample and a Community Sample

Psychopathy is often described as a constellation of personality characteristics encompassing features such as impulsivity and antisociality, and a lack of empathy and guilt. Although the use of self-reports to assess psychopathy is still debated, there are distinct advantages to such measures and recent research suggests that they may not be as problematic as previously thought. This study further examined the reliability and validity of the Triarchic Psychopathy Measure (TriPM) in a community sample (N = 496) and forensic psychiatric patient sample (N = 217). Results indicated excellent internal consistencies. Additionally, the TriPM total and subscale scores related as expected to different subscales of the Psychopathic Personality Inventory –Revised (PPI-R) and to the Reactive and Proactive Aggression Questionnaire, reflecting good construct validity. Most importantly, ROC curve analyses showed that the TriPM evidenced better discrimination between the community sample and forensic psychiatric patients than the PPI-R. The current study extends the existent evidence demonstrating that the TriPM can be used as an efficient self-report instrument.     

Factors associated with experts' opinions regarding criminal responsibility in The Netherlands

In many jurisdictions, offenders need to have freely chosen to commit their crimes in order to be punishable. A mental defect or disorder may be a reason for diminished or total absence of criminal responsibility and may remove culpability. This study aims to provide an empirically based understanding of the factors on which experts base their judgements concerning criminal responsibility. Clinical, demographic and crime related variables, as well as MMPI-2 profiles, were collected from final reports concerning defendants of serious crime submitted to the observation clinic of the Dutch Ministry of Justice for a criminal responsibility assessment. Criminal responsibility was expressed along a five-point scale corresponding to the Dutch legal practice. Results showed that several variables contributed independently to experts' opinions regarding criminal responsibility: diagnosis (Axis I and II), cultural background, type of weapon used in committing the crime, and whether the defendant committed the crime alone or with others. In contract to jurisdictions involving a sane/insane dichotomy, the Dutch five-point scale of criminal responsibility revealed that Axis II personality disorders turned out to be mostly associated with a diminished responsibility. MMPI-2 scores also turned out to have a small contribution to experts' opinions on criminal responsibility, independently of mere diagnostic variables. These results suggest that experts base their judgements not only on the presence or absence of mental disorders, but also on cultural and crime related characteristics, as well as dimensional information about the defendant's personality and symptomatology.     

On the emergence of deprivation-reducing behaviors: Subliminal priming of behavior representations turns deprivation into motivation

Building on recent research into the emergence of human motivation and goal pursuit in the absence of the conscious awareness of the source of this pursuit, the present article aimed to shed light on how states of deprivation (e.g., deprivation of fluid) actually produce the motivation and corresponding behavior that lifts the deprivation. Two studies established that when participants were relatively deprived of fluids, they experienced enhanced motivation to drink and consumed more fluid in an alleged tasting test, and these effects were more pronounced when the concept of drinking was rendered accessible by subliminal priming. These results suggest that specific motivational goal states and corresponding behaviors do not arise directly from deprivation per se, but that accessible goal-related cognitions play a role in this process. Implications for theory and research on deprivation and non-conscious goal pursuit are briefly discussed.     

Nonconscious goal pursuit and the surmounting of physical and social obstacles

The ability to overcome obstacles is widely regarded as a sign of motivation. Building on recent research on nonconscious goal pursuit, two experiments are presented that test whether activating the goal of helping outside people's awareness by exposure to social stereotypes causes them to overcome physical and social obstacles. Experiment 1 established that although overall participants were less inclined to pick up a tissue that was accidentally dropped on the floor by the experimenter when this tissue was dirty instead of clean, they were able to overcome their aversion toward picking up the physical object when they were primed with the mental representation of a social group (e.g., nurse) containing the goal of helping. Results were replicated in Experiment 2, in which participants had to overcome a social obstacle by providing feedback to a student of a negatively evaluated ethnic minority group, and explanations in terms of demand characteristics and mood were excluded. Implications for the literature on nonconscious goal pursuit are briefly discussed. Copyright © 2007 John Wiley & Sons, Ltd.     

Debating ethical expertise

This paper explores the relevance of the debate about ethical expertise for the practice of clinical ethics. We present definitions, explain three theories of ethical expertise, and identify arguments that have been brought up to either support the concept of ethical expertise or call it into question. Finally, we discuss four theses: the debate is relevant for the practice of clinical ethics in that it (1) improves and specifies clinical ethicists' perception of their expertise; (2) contributes to improving the perception of moral competence of non-ethicists; (3) gives insight into complementary styles of argumentation of ethicists and non-ethicists; and (4) contributes to the awareness of the problem of profession-building of (clinical) ethicists.     

Neuroticism and attachment insecurity as predictors of bereavement outcome

Adult attachment dimensions as well as the personality trait neuroticism have been shown to be related to psychological adjustment after bereavement. No investigations so far have studied the relative contribution of these constructs to grief and depression. In our study of 219 bereaved parents, the two adult attachment dimensions, attachment anxiety and attachment avoidance, were compared to the personality trait neuroticism in predicting psychological adjustment. The attachment dimensions explained a unique part over and above neuroticism, but contrary to expectations, neuroticism explained more variance than attachment dimensions. Implications are discussed.     

In search of the nonconscious sources of goal pursuit: Accessibility and positive affective valence of the goal state

Two experiments tested the hypothesis that the mere priming of the representation of a goal state motivates people to pursue this state to the extent that it is associated with positive affect. In Experiment 1, all participants completed an affective priming task in which the goal concept of “socializing” was primed and tested for positive valence. Subsequently, they were given an instrumental task which provided the opportunity to pursue that state. It was established that participants put more effort in the task to attain the primed goal state when the implicitly assessed affective valence of the state was more positive. Experiment 2 replicated and extended these effects by showing that a stronger association of the goal state with positive affect—as assessed by the EAST—led to more effort to attain the state, but only when “socializing” was primed.     

Behavioral cues to others’ motivation and goal pursuits: The perception of effort facilitates goal inference and contagion

Recent research demonstrates that people spontaneously, i.e., without conscious intent, infer and pursue the goals perceived in others’ behavior, a phenomenon termed goal contagion [Aarts, H., Gollwitzer, P., & Hassin, R. R. (2004). Goal contagion: perceiving is for pursuing. Journal of Personality and Social Psychology, 87, 23-27]. Three experiments extend this work by studying the basic role of perceived behavioral effort in goal inference and pursuit. In an adaptation of the Animated Film Technique, participants were exposed to a movie featuring movements of a ball that implied the goal of helping. The amount of effort in pursuing the implied goal was experimentally varied. Results showed that an increase in perceived effort led to stronger inferences of the implied goal, as was established by enhanced accessibility of the goal representation in a word completion and lexical decision task. Furthermore, as a result of these inferences, participants more strongly pursued the inferred goal of helping. Implications for research on goal inferences and pursuit are briefly discussed.