Hand preference in attention deficit hyperactivity disorder

In our Outpatient Department, we studied 56 subjects (41 males, 15 females; aged 5-16 yr.) with Attention Deficit Hyperactivity Disorder (ADHD) with respect to hand use in functional tasks via parental report. Left-hand use was markedly preferred, compared to that of a control group, more for complex than simple and for external (touching food and objects) than internal (scratching, rubbing eyes) tasks, suggesting a deficit in cerebral control of right-hand use. More patients were reported to have a left-hand preference than in the non-ADHD population. Furthermore, extent of laterality was greater for complex than simple external tasks and for external than for internal.     

Posttraumatic stress and depressive symptoms in a college population one year after the September 11 attacks: the effect of proximity

As a follow-up to our earlier report [Behav. Res. Ther., in press] on the level of posttraumatic stress symptoms (PTSS), depressive symptoms, and frequency of diagnoses of probable posttraumatic stress disorder (PTSD) among college students at three public universities (Albany, NY, Augusta, GA, and Fargo, ND) resulting from the September 11, 2001. Terrorist attacks, we surveyed comparable groups of students (total, n = 1313) from these three institutions in the weeks following the first anniversary (2002) of the attacks. We found proximity effects (Albany higher than Augusta which was higher than Fargo) for PTSS and depressive symptoms but not for frequency of diagnoses of probable PTSD. Within the Albany site data, proximity of county of residence to New York City (NYC) also showed a proximity effect on PTSS. Although depressive symptoms were significantly different in 2002 versus 2001, the arithmetic differences in PTSS or in frequency of diagnoses of probable PTSD were not significant. The September 11 attacks continued to exert a psychic toll on college students even a year later.     

Histidine-decarboxylase knockout mice show deficient nonreinforced episodic object memory, improved negatively reinforced water-maze performance, and increased neo- and ventro-striatal dopamine turnover

The brain's histaminergic system has been implicated in hippocampal synaptic plasticity, learning, and memory, as well as brain reward and reinforcement. Our past pharmacological and lesion studies indicated that the brain's histamine system exerts inhibitory effects on the brain's reinforcement respective reward system reciprocal to mesolimbic dopamine systems, thereby modulating learning and memory performance. Given the close functional relationship between brain reinforcement and memory processes, the total disruption of brain histamine synthesis via genetic disruption of its synthesizing enzyme, histidine decarboxylase (HDC), in the mouse might have differential effects on learning dependent on the task-inherent reinforcement contingencies. Here, we investigated the effects of an HDC gene disruption in the mouse in a nonreinforced object exploration task and a negatively reinforced water-maze task as well as on neo- and ventro-striatal dopamine systems known to be involved in brain reward and reinforcement. Histidine decarboxylase knockout (HDC-KO) mice had higher dihydrophenylacetic acid concentrations and a higher dihydrophenylacetic acid/dopamine ratio in the neostriatum. In the ventral striatum, dihydrophenylacetic acid/dopamine and 3-methoxytyramine/dopamine ratios were higher in HDC-KO mice. Furthermore, the HDC-KO mice showed improved water-maze performance during both hidden and cued platform tasks, but deficient object discrimination based on temporal relationships. Our data imply that disruption of brain histamine synthesis can have both memory promoting and suppressive effects via distinct and independent mechanisms and further indicate that these opposed effects are related to the task-inherent reinforcement contingencies.     

Consumer information processing strategies in middle and late adulthood

The purpose of the present study was to investigate the extent to which performance of a complex cognitive task of a type resembling that encountered in everyday life is maintained through adulthood. A total of 80 subjects participated; 20 in their thirties, 20 in their fifties, 20 in their sixties, and 20 in their seventies. Subjects were asked to make preference judgments with respect to 32 pocket-size notebooks of a sort they might encounter as consumers in a stationery or variety store. Independently, they were also asked to express their preferences with respect to each of the four dimensions on which the notebooks varied. With only minor differences across age groups, most subjects demonstrated the ability to integrate their individual dimension preferences into a complex preference judgment of an object embodying those dimensions, in a logically consistent manner.     

Das tschechoslowakische Modell des Sozialismus — Ursachen,Ziele, Folgen

Ohne Zusammenfassung     

Local and Relational Aspects of Face Distinctiveness

Distinctiveness contributes strongly to the recognition and rejection of faces in memory tasks. In four experiments we examine the role played by local and relational information in the distinctiveness of upright and inverted faces. In all experiments subjects saw one of three versions of a face: original faces, which had been rated as average in distinctiveness in a previous study (Hancock, Burton, & Bruce, 1996), a more distinctive version in which local features had been changed ( D-local ), and a more distinctive version in which relational features had been changed ( D-rel ). An increase in distinctiveness was found for D-local and D-rel faces in Experiment 1 (complete faces) and 3 and 4 (face internals only) when the faces had to be rated in upright presentation, but the distinctiveness of the D-rel faces was reduced much more than that of the D-local versions when the ratings were given to the faces presented upside-down (Experiments 1 and 3). Recognition performance showed a similar pattern: presented upright, both D-local and D-rel revealed higher performance compared to the originals, but in upside-down presentation the D-local versions showed a much stronger distinctiveness advantage. When only internal features of faces were used (Experiments 3 and 4), the D-rel faces lost their advantage over the Original versions in inverted presentation. The results suggest that at least two dimensions of facial information contribute to a face's apparent distinctiveness, but that these sources of information are differentially affected by turning the face upside-down. These findings are in accordance with a face processing model in which face inversion effects occur because a specific type of information processing is disrupted, rather than because of a general disruption of performance.