A suit for protecting chronically implanted devices in monkeys

The plastic barrel suit provides complete protection of chronically implanted fistulas and electrical connectors. The lost time, expense, and the frustrations of having these devices damaged was avoided.     

Psychophysical parameters of the perception of orally-retained liquid bulk

Bulk of liquid held in the mouth may be judged on its subjective volume. Over the range I ml-31 ml, scaling by the constant method and by ratio estimation yielded a Weber fraction which was not constant and decreased with stimulus magnitudes and a psychophysical power function with an exponent of 0.96. A “negative threshold” effect is reported.     

Experimental design symbolization and model derivation

A method of design symbolization (DS) is given for a class of designs in which all factors are related by complete crossing or by nesting. Characterization of acceptable DS's, and logical relational properties are given. It is shown how the design model can be obtained from the DS.The preparation of this article was supported by NIH Grant GM-11128, and by grants to the Institute of Human Learning by NSF and NIH.     

The 3RT Test: Three reaction time tasks for IBM PC computers

The 3RT Test consists of a simple, a choice, and a conditional reaction time (RT) task. The three tasks involve comparable visual stimuli and require identical manual responses, but they differ in the complexity of cognitive processing required. The nonverbal stimuli convey commonly known meanings. Responses can be made either on the keyboard or on response keys connected to the computer’s serial port. The computer’s internal timer/counter is used for millisecond timing. The test administration program allows flexible setting of the test conditions. The data analysis program provides summary data not only for each RT task as a whole, but also for separate trial types within each task. Summary statistics include measures of variation and central value that are not affected by extreme scores. In addition to laboratory studies with normal adults, the 3RT Test is suitable for life-span developmental studies, cross-cultural comparisons, and other uses in various clinical settings.     

Potentiation of the pressor response to stress by tolbutamide in dogs

Tolbutamide has previously been shown to amplify the pressor effects of “exogenous” catecholamines in conscious dogs, possibly due to sensitization of the α₁-adrenoreceptor-mediated vasoconstriction. The objective of this study was to examine if tolbutamide also amplifies the pressor effects of “endogenous” catecholamines released during psychological stress (classical Pavlovian aversive conditioning). Experiments were conducted in β-adrenoreceptor-blocked (propranolol, 1 mg/kg, i.v.) conscious dogs (n=4) trained in classical aversive conditioning. Conditioning was accomplished by following a tone (CS+) with a 1/2 second shock; another tone (CS-) was not followed by any shock and served as control. With saline pretreatment, aversive conditioning (i.e., CS+) increased mean arterial pressure (MAP) only by approximately 4.7% when compared to CS-, whereas with tolbutamide (45 mg/kg, i.v.) pretreatment, the increase in MAP induced by CS+ beyond what was induced by the CS- (approximately 6.2%) was significantly (p<0.05) larger than that with saline pretreatment. In isolated canine femoral arterial segments (n=4), the vasoconstrictor effect of phenylephrine (an α₁-agonist) at 5×10^?6M (which was the EC₅₀ value) was amplified by 2×10^?2M of tolbutamide from 54.0±2.0% to 66.9±2.1%. In conclusion, tolbutamide amplifies the pressor effects of “endogenous” catecholamines in conscious dogs, possibly by sensitization of the α₁-adrenoreceptor-mediated vasoconstriction. This mechanism of action is novel and has not been reported with other agents.     

Parental conflict and children's coping styles in litigating separated families: Relationships with children's adjustment

The influence of interparental verbal and physical aggression, children's coping styles, and relevant demographic factors on children's adjustment was examined in a group of 52 families who were disputing custody and/or access arrangements after separation. It was hypothesized that parental conflict and specific children's coping strategies (i.e., cognitive redefinition and social support seeking) would be important predictors of children's adjustment. Consistent with previous research, aggressive styles of resolving conflict between parents were related to more frequent and severe behavior problems and diminished competence among children. Conversely, greater flexibility in coping and greater use of cognitive coping strategies among children were related to decreased behavioral disturbance. The unique and combined influence of these variables is discussed.This research was supported in part through a grant from the LaMarsh Research Programme on Violence and Conflict Resolution, York University, Toronto, Ontario. The author acknowledges the help of Cathy Melville and Susan Dickens in the data analyses. In addition, the author thanks the staff and families at the Toronto and London, Ontario, Family Court clinics who participated in this project.