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In this study, the authors aimed to identify patterns of autonomic dysfunction and neurocognitive deficit recovery. The authors performed laboratory assessments on 66 patients with schizophrenia immediately after an acute psychotic episode and 6, 12, and 18 months later. Shortly after the psychotic episode, the patients displayed cardiovascular hyperarousal at rest, cardiovascular and electrodermal hyporeactivity during 2 Continuous Performance Tasks (CPTs) and deficits in 2 behavioral CPT measures (i.e., reaction time and omission error rate) compared with 29 normal controls. In the subsequent postpsychotic course, changes indicative of a process of recovery occurred in all measurement areas, although with regard to autonomic hyporeactivity amelioration was limited to a subgroup of schizophrenics with complete and persistent symptomatic remission. Neurocognitive improvement in CPTs did not appear to depend on unimpaired autonomic reactivity mechanisms. 相似文献
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Extensions of Natural Deduction to Substructural Logics of IntuitionisticLogic are shown: Fragments of Intuitionistic Linear, Relevantand BCK Logic. Rules for implication, conjunction, disjunctionand falsum are defined, where conjunction and disjunction respectcontexts of assumptions. So, conjunction and disjunction areadditive in the terminology of linear logic. Explicit contractionand weakening rules are given. It is shown that conversionsand permutations can be adapted to all these rules, and thatweak normalisation and subformula property holds. The resultsgeneralise to quantification. 相似文献
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We examined selective attention to threat stimuli as a function of individual differences in adult attachment. Participants completed a dot-probe task in which a general threat word, attachment-related threat word, general positive or attachment-related positive word was presented together with a neutral word. Results showed that attachment anxiety and avoidance were associated with an attentional bias away from attachment threat words. This attentional avoidance effect was best predicted by the interaction between attachment anxiety and avoidance and not by their unique main effects. The findings are discussed in terms of attachment theory and its relation to attentional biases observed in psychopathology. 相似文献
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Ernst M. Falzeder John C. Burnham 《The International journal of psycho-analysis》2007,88(5):1223-1244
An eyewitness account provides evidence of a significant clandestine effort to neutralize the legitimacy and authority of psychoanalysis. In a letter, the witness confirms the existence of a perfectly staged concerted action among German psychiatrists against Freud's influence in 1913. Their congress in Breslau was meant to present the united front of German psychiatrists, who were going on record as being against psychoanalysis and, in that context, to give Eugen Bleuler, a leading psychiatrist, whose (however half-hearted) support for psychoanalysis had alarmed his colleagues, a public opportunity for back-pedalling. The letter shows that Freud and his allies were not the only ones who tried to manage an intellectual movement by using informal networks and 'behind the scenes' manoeuvring. 相似文献
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Stephan Heinzel Stefanie Schulte Johanna Onken Quynh-Lam Duong Thomas G. Riemer Andreas Heinz 《Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition》2014,21(2):146-173
Previous studies on working memory training have indicated that transfer to non-trained tasks of other cognitive domains may be possible. The aim of this study is to compare working memory training and transfer effects between younger and older adults (n = 60). A novel approach to adaptive n-back training (12 sessions) was implemented by varying the working memory load and the presentation speed. All participants completed a neuropsychological battery of tests before and after the training. On average, younger training participants achieved difficulty level 12 after training, while older training participants only reached difficulty level 5. In younger participants, transfer to Verbal Fluency and Digit Symbol Substitution test was found. In older participants, we observed a transfer to Digit Span Forward, CERAD Delayed Recall, and Digit Symbol Substitution test. Results suggest that working memory training may be a beneficial intervention for maintaining and improving cognitive functioning in old age. 相似文献
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Matthew B. Pontifex Andrew C. Parks Patrick C. O’Neil Adriel R. Egner Joseph T. Warning Karin A. Pfeiffer Kimberly M. Fenn 《Cognitive, affective & behavioral neuroscience》2014,14(3):1132-1141
Epidemiological investigations have revealed increases in the prevalence of sedentary behaviors in industrialized societies. However, the implications of those lifestyle choices and related cardiorespiratory fitness levels for memory function are not well-understood. To determine the extent to which cardiorespiratory fitness relates to the integrity of multiple memory systems, a cross-sectional sample of young adults were tested over the course of 3 days in areas related to implicit memory, working memory, long-term memory, and aerobic fitness. Findings revealed an association between aerobic fitness and memory function such that individuals with lower cardiorespiratory fitness exhibited poorer implicit memory performance and poorer long-term memory retention. These data indicate that cardiorespiratory fitness may be important for the optimal function of neural networks underlying these memory systems. 相似文献