Catechol-O-methyltransferase Val158Met genotype affects neural correlates of aversive stimuli processing

It was previously shown that variation of the catechol-O-methyltransferase (COMT) gene modulates brain activity during the processing of stimuli with negative valence, but not for pleasant stimuli. Here, we tested whether the COMT genotype also modulates the electrophysiological correlates of emotional processing and explored whether the environmental factor of life stress influences this effect. Using the early posterior negativity (EPN) paradigm, event-related brain potentials were measured in 81 healthy individuals during the processing of pictures that evoked emotions of positive and negative valence. As was hypothesized, the COMT genotype affected the EPN amplitudes for unpleasant stimuli, but not for pleasant ones. Specifically, Met/Met carriers respond more sensitively to unpleasant stimuli, as compared with Val/Val carriers. We did not find evidence that life stress moderates the effect of the COMT genotype on emotional stimuli processing.     

A Model of Therapist Competencies for the Empirically Supported Cognitive Behavioral Treatment of Child and Adolescent Anxiety and Depressive Disorders

While a plethora of cognitive behavioral empirically supported treatments (ESTs) are available for treating child and adolescent anxiety and depressive disorders, research has shown that these are not as effective when implemented in routine practice settings. Research is now indicating that is partly due to ineffective EST training methods, resulting in a lack of therapist competence. However, at present, the specific competencies that are required for the effective implementation of ESTs for this population are unknown, making the development of more effective EST training difficult. This study therefore aimed to develop a model of therapist competencies for the empirically supported cognitive behavioral treatment of child and adolescent anxiety and depressive disorders using a version of the well-established Delphi technique. In doing so, the authors: (1) identified and reviewed cognitive behavioral ESTs for child and adolescent anxiety and depressive disorders, (2) extracted therapist competencies required to implement each treatment effectively, (3) validated these competency lists with EST authors, (4) consulted with a panel of relevant local experts to generate an overall model of therapist competence for the empirically supported cognitive behavioral treatment of child and adolescent anxiety and depressive disorders, and (5) validated the overall model with EST manual authors and relevant international experts. The resultant model offers an empirically derived set of competencies necessary for effectively treating children and adolescents with anxiety and depressive disorders and has wide implications for the development of therapist training, competence assessment measures, and evidence-based practice guidelines for working with this population. This model thus brings us one step closer to bridging the gap between science and practice when treating child and adolescent anxiety and depression.     

The role of socio-communicative rearing environments in the development of social and physical cognition in apes

The cultural intelligence hypothesis (CIH) claims that humans’ advanced cognition is a direct result of human culture and that children are uniquely specialized to absorb and utilize this cultural experience ( Tomasello, 2000 ). Comparative data demonstrating that 2.5‐year‐old human children outperform apes on measures of social cognition but not on measures of physical cognition support this claim ( Herrmann et al., 2007 ). However, the previous study failed to control for rearing when comparing these two species. Specifically, the human children were raised in a human culture whereas the apes were raised in standard sanctuary settings. To further explore the CIH, here we compared the performance on multiple measures of social and physical cognition in a group of standard reared apes raised in conditions typical of zoo and biomedical laboratory settings to that of apes reared in an enculturated socio‐communicatively rich environment. Overall, the enculturated apes significantly outperformed their standard reared counterparts on the cognitive tasks and this was particularly true for measures of communication. Furthermore, the performance of the enculturated apes was very similar to previously reported data from 2.5‐year‐old children. We conclude that apes who are reared in a human‐like socio‐communicatively rich environment develop superior communicative abilities compared to apes reared in standard laboratory settings, which supports some assumptions of the cultural intelligence hypothesis.     

Chunking versus foraging search patterns by rats in the hierarchically baited radial maze

Rats were exposed to a radial maze containing six black smooth arms and six wire-grid-covered arms and a striped 'exit arm' in experiment 1. The probability of a black or grid arm being baited (5/6 vs 1/6) with sunflower seeds was associated with its proximal cue for some rats (the Relevant Arm Cue group) but not for others (the Irrelevant Arm Cue group). All rats could terminate a trial and receive a highly preferred morsel of apple by entering the exit arm only after having sampled all six seed-baited arms. Relevant Arm Cue rats usually chose some arms from the more densely baited set before choosing an arm from the less densely baited set and made fewer reentries than Irrelevant Arm Cue rats. Although such clustered, higher choice accuracy in the Relevant Arm Cue group corresponds to human clustered, better recall of verbal items from lists hierarchically organized by categories, these rats did not similarly exhaustively retrieve items (arm locations). That is, when required to terminate a trial by entering the 'exit' arm for an apple morsel after having sampled all seed-baited arms, both groups were equally unable to withhold making nonrewarded premature exits. This nonexhaustive foraging search pattern was maintained in the next two experiments in which the radial maze was reduced to three black and three grid arms along with the striped 'exit' arm and in which black and grid arm cues were paired with number of seeds (eight or one) in an arm for Relevant Arm Cue rats. Although Relevant Arm Cue rats displayed perfect clustering by entering all eight-seeded arms before a one-seeded arm, they made more premature exits and reentries into eight-seeded arms in experiment 2 or when forced to enter all eight-seeded arms in experiment 3 than did Irrelevant Arm Cue rats. These foraging tendencies prevent accurate estimations of the amount of information (i.e., arm locations) rats can 'chunk'. Electronic Publication     

The use of perceptual features in categorization by orangutans (<Emphasis Type="Italic">Pongo abelli</Emphasis>)

The extent to which categorization of natural classes in animals reflects a generalization based on perceptual similarity versus an abstract conceptual representation remains unclear. Here, two experiments were conducted to identify the perceptual features used by orangutans when categorizing pictures. In Experiment 1, subjects were trained and tested for transfer on a concrete discrimination (gorillas or orangutans vs. other primates). Analysis of performance on both positive and negative exemplars revealed that performance was best on photos with faces, particularly close-ups. Moreover, error trials did not seem to reflect instances of mistaken identity, but rather, exemplars that may have been distracting for other reasons, such as novel coloration or morphology. In Experiment 2, photos were modified to test the effects of various features. Color modifications caused the biggest decrease in performance, and eye modifications also affected performance deleteriously. Therefore, two perceptual features, namely eye regions and color, played a key role in subjects' ability to categorize. However, performance based on an underlying concept cannot be ruled out, because both of these features are highly relevant in terms of defining category membership. Although a subset of features was identified as playing a key role in categorization, these features differed depending on whether feature-use was studied indirectly, as in Experiment 1, or directly, as in Experiment 2.     

Contingency experiences of 3-month-old children and their relation to later developmental achievements

In this study, the authors investigated the relation between early social contingency experiences and infants' competencies to detect nonsocial contingencies. In this study of 87 three-month-old infants, the authors operationalized early social contingencies as prompt, contingent maternal responses and coded microanalytically on the basis of video-recorded mother-infant interactions. The authors assessed competence to detect nonsocial contingencies by 2 methods: (a) the mobile conjugate reinforcement paradigm, which focuses on detecting contingencies between the infants' actions (kicking) and nonsocial consequences (mobile moving) and (b) the visual expectation paradigm, which focuses on detecting contingencies between 1 event (a smiley face projected on a screen) that was followed by a 2nd event (a complex picture projected on the other side of the screen). The results showed that early social contingencies are related to the competency to detect nonsocial action-consequence contingencies in the mobile conjugate reinforcement paradigm.