Visions and Ethics in Current Discourse on Human Enhancement

Since it is now broadly acknowledged that ethics should receive early consideration in discourse on emerging technologies, ethical debates tend to flourish even while new fields of technology are still in their infancy. Such debates often liberally mix existing applications with technologies in the pipeline and far-reaching visions. This paper analyses the problems associated with this use of ethics as “preparatory” research, taking discourse on human enhancement in general and on pharmaceutical cognitive enhancement in particular as an example. The paper will outline and discuss the gap between the scientific and technological state of the art and the ethical debates, pointing out epistemic problems in this context. Furthermore, it will discuss the future role of genuine ethical reflection in discourse on human enhancement, arguing also that such discourse needs to include a technology assessment—in the broad sense of the term—which encompasses, inter alia, anthropological perspectives and aspects of social theory.     

Simulating Ordinal Data

The increasing use of ordinal variables in different fields has led to the introduction of new statistical methods for their analysis. The performance of these methods needs to be investigated under a number of experimental conditions. Procedures to simulate from ordinal variables are then required. In this article, we deal with simulation from multivariate ordinal random variables. We propose a new procedure for generating samples from ordinal random variables with a prespecified correlation matrix and marginal distributions. Its features are examined and compared with those of its main competitors. A software implementation in R is also provided along with examples of its application.     

A Different Approach to Dependence Analysis

This article focuses on a statistical tool for dependence analysis in scientific research. Starting from a recent index of concordance for a multiple linear regression model, a coefficient suitable in catching any monotonic dependence relationship between a dependent variable and an independent variable is derived and discussed. Given its interpretation in terms of monotonic dependence, it is called monotonic dependence coefficient (MDC). It is appropriate to all contexts where the dependent variable is quantitative (continuous or discrete) and the independent variable is at least of ordinal nature; tied data are also allowed. MDC’s adequacy is validated through Monte Carlo simulations led by taking into account different scenarios of dependence. Finally, an application to real data is provided to stress MDC’s capability of detecting dependence relationships between two variables, even if some pieces of information about original data are lost.     

Community responses to a suicidal crisis: implications for suicide prevention

We conducted a cross‐sectional, random‐digit‐dial survey to evaluate public responses to a hypothetical question: “If someone you knew was suicidal, what would you do first?” Younger people were more likely to call a suicide hotline, and less likely to go to an emergency room (ER) or call 911; immigrants (in the U.S. <15 years) were more likely to call 911, and less likely to call a suicide hotline; African Americans were more likely to go to the ER and call 911; Hispanics were more likely to call 911 but less likely to call a suicide hotline. These results suggest that public messages about hotlines and emergency options for suicidal patients need to be tailored to relevant population characteristics including age, education, ethnicity, and language preferences.     

Permanent Deacons and Non-profit Directors: Comparing Leadership Styles Among Facilitators of Community Agencies

Permanent deacons in the Roman Catholic Church (all male) are active in their local community and congregation mobilizing faith formation events, liturgical services, and community social action programs, yet not much is known about their leadership style. The present study compared U.S. 203 permanent deacons with 202 male community-based directors of non-profit agencies on their self-reported transformational leadership style, assessed by five subscales of competencies. Deacons and directors differed significantly on three subscales; deacons scored higher on the promoting positive values and leadership as service subscales, while directors scored higher on the building a sustainable organization subscale. Results suggested that the transformational leadership styles of U.S. permanent deacons is more value and service-centered, and, in comparison, community-based non-profit leaders seem to focus more on the group’s structure and health of their organization.     

Testing the effects of end-goal during reach-to-grasp movements in Parkinson’s disease

Previous evidence suggests that hand shaping during reaching is modulated by the presence and the nature of the end-goal following object’s grasp. Here we test whether such modulation is maintained in Parkinson’s disease (PD). Six participants with PD and six healthy participants took part in the study. Participants were requested to reach towards a bottle filled with water, and then: (1) grasp it without performing any subsequent action; (2) grasp it and place it accurately on a target area; (3) grasp it and pour its contents within a container. The results showed that participants shaped their hand differently depending on the presence or absence of an action following object’s grasp. However, the request to perform an action after grasp determined a modulation of hand kinematics which was delayed for PD than for control participants. Further, whereas for control participants the nature of the end-goal determined a modulation of hand shaping, for PD patients such modulation was not evident. Data are discussed in terms of the role played by basal ganglia in implementing anticipatory mechanisms for the control of manipulative activities. We contend that in PD patients these mechanisms are not totally compromised, but their implementation depends on the action information that has to be anticipated.     

Correspondence of children's anticipated vocations, perceived competencies, and interests: Results from an Italian sample

Relations among anticipated vocations, self-assessments of competence, and interests in sample of 190 Italian children were examined. Children were asked what activities they liked, those they thought they were good at, and what job they expected when they grew up. The responses were coded into RIASEC Holland codes and agreement across the three questions was examined using kappa statistics. Results indicated that there was no relation between anticipated occupations and either interest or perceived competence. Thus, these anticipated occupations appear to be based on unrealistic criteria and the validity of studying such early expressions of interest is questionable. Conversely, results demonstrated a correspondence between interest and competence and this correspondence was similar for boys and girls and increased with age.     

Developments in the Debate on Nanoethics: Traditional Approaches and the Need for New Kinds of Analysis

This paper aims to review different discourses within the emerging field of ethical reflection on nanotechnology. I will start by analysing the early stages of this debate, showing how it has been focused on searching for legitimacy for this sphere of moral inquiry. I will then characterise an ethical approach, common to many authors, which frames ethical issues in terms of risks and benefits. This approach identifies normative issues where there are conflicts of interest or where challenges to the fundamental values of our society arise. In response to the limitations of this approach, other commentators have called for more profound analysis of the limits of our knowledge, and have appealed to values, such as sustainability or responsibility, which should, they suggest, inform nanotechnological development (I will define this approach as a “sophisticated form of prudence”). After showing the ways in which these frameworks are limited, I will examine more recent developments in debates on nanoethics which call for the contextualisation of ethical discourse in its ontological, epistemic and socio-economic and political reflections. Such contextualisation thus involves inquiry into the ‘metaphysical research program’ (MRP) of nanotechnology/ies and analysis of the socio-economic, political and historical reality of nano. These ideas offer genuinely new insights into the kind of approach required for nanoethical reflection: they recover a sense of the present alongside the need to engage with the past, while avoiding speculation on the future.     

Bridging professional and mutual-help: An application of the transtheoretical model to the mutual-help organization

The authors suggest that the mental health system of the nation could benefit by more fully embracing the idea of mutual-help (i.e., self-help), and this collaboration could be facilitated by the utilization of a well-established clinical theory to elucidate the psychological processes at work within mutual-help organizations. The processes of change of the transtheoretical model is offered as one potential framework. This well-established model has been used to help psychologists better understand clinical and professional phenemonena, but, to date, has been used less frequently with non-professional interventions. This article applies the ten processes of change of the transtheoretical model to mutual-help organizations, focusing on four groups, including Alcoholics Anonymous (AA), Oxford House, GROW, and Schizophrenics Anonymous. The advantages of the transtheoretical model and its potential ability to act as a common language across clinical professionals and mutual-help organizations are discussed. In addition, advantages of bolstering the present mental health system using combinations of both forms of care along the recovery continuum are described.