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Hayden EP Klein DN Sheikh HI Olino TM Dougherty LR Dyson MW Durbin CE Singh SM 《Emotion (Washington, D.C.)》2010,10(5):696-702
Association studies of the serotonin transporter promoter polymorphism (5-HTTLPR) and negative emotionality (NE) are inconclusive. However, emerging evidence suggests that the association between this polymorphism and NE may be influenced by levels of another temperament trait, positive emotionality (PE). Therefore, this study examined whether the association between the 5-HTTLPR and NE was moderated by PE. A community sample of 413 three-year-old children completed a standardized battery of laboratory tasks designed to tap temperamental emotionality. Children were also genotyped for the 5-HTTLPR. No direct association between 5-HTTLPR genotype and NE was found. However, the interaction of child PE and NE predicted 5-HTTLPR genotype. Furthermore, children with a short allele who were also low in PE had significantly greater NE than children without a short allele or children with high PE. Our findings suggest that the short allele of the 5-HTTLPR is associated with NE only in the context of low PE. Inconsistent links between NE and this gene in previous research may stem from the failure to consider other temperament traits that moderate associations. 相似文献
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Hayden EP Bodkins M Brenner C Shekhar A Nurnberger JI O'Donnell BF Hetrick WP 《Journal of abnormal psychology》2008,117(1):164-170
Dysregulation in behavioral activation system (BAS) activity has been implicated in the pathogenesis of bipolar disorder (BPD). To characterize BAS activity and related facets in this disorder, the authors compared 59 participants with BPD to 44 controls on multiple measures of BAS activity, including a standardized behavioral task, self-reports, and electroencephalographic indexes of regional cortical activity. Levels of putative BAS activity differed depending on assessment strategy. When a behavioral task indexing reward sensitivity was used, euthymic BPD patients showed evidence of higher BAS activity than either control participants or patients who were in a mood episode. Following a mood induction procedure designed to elicit BAS activity, currently episodic patients showed relatively greater left anterior cortical activity than either euthymic or control participants. Implications of the findings for future research on BPD vulnerability are described. 相似文献
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Hayden Noel 《Journal of Consumer Psychology》2006,16(3):306-320
We explore the extent to which repeating a brand‐attribute association will have a greater effect on recall when the 2 repetitions occur at different points in time rather than immediately after each other. Cued recall is generally better when the repeated items are separated. However, this depends on the extent to which information is organized by brand as well as by attribute, the number of attribute items presented about the brand, and the relatedness of the attributes. 相似文献
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Peel Hayden J. Royals Kayla A. Chouinard Philippe A. 《Journal of psycholinguistic research》2022,51(1):1-15
Journal of Psycholinguistic Research - It is widely assumed that subliminal word priming is case insensitive and that a short SOA (<?100 ms) is required to observe any... 相似文献
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The ability to compute probability, previously shown in nonverbal infants, apes, and monkeys, was examined in three experiments with pigeons. After responding to individually presented keys in an operant chamber that delivered reinforcement with varying probabilities, pigeons chose between these keys on probe trials. Pigeons strongly preferred a 75% reinforced key over a 25% reinforced key, even when the total number of reinforcers obtained on each key was equated. When both keys delivered 50% reinforcement, pigeons showed indifference between them, even though three times more reinforcers were obtained on one key than on the other. It is suggested that computation of probability may be common to many classes of animals and may be driven by the need to forage successfully for nutritional food items, mates, and areas with a low density of predators. 相似文献
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Pearson JM Heilbronner SR Barack DL Hayden BY Platt ML 《Trends in cognitive sciences》2011,15(4):143-151
When has the world changed enough to warrant a new approach? The answer depends on current needs, behavioral flexibility and prior knowledge about the environment. Formal approaches solve the problem by integrating the recent history of rewards, errors, uncertainty and context via Bayesian inference to detect changes in the world and alter behavioral policy. Neuronal activity in posterior cingulate cortex - a key node in the default network - is known to vary with learning, memory, reward and task engagement. We propose that these modulations reflect the underlying process of change detection and motivate subsequent shifts in behavior. 相似文献
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Hayden EP Klein DN Dougherty LR Olino TM Dyson MW Durbin CE Sheikh HI Singh SM 《Psychological science》2010,21(11):1678-1685
The brain-derived neurotrophic factor (BDNF) gene is a plausible candidate for early-emerging negative emotionality (NE), and evidence suggests that the effects of this gene may be especially salient in the context of familial risk for child maladjustment. We therefore examined whether the single-nucleotide polymorphism producing a valine-to-methionine substitution at codon 66 (val66met) of the BDNF gene was associated with childhood NE, in the context of parental depression and relationship discord. A sample of 413 three-year-old children was assessed for NE using standardized laboratory measures. The children's parents completed clinical interviews as well as a measure of marital satisfaction. Children with at least one BDNF methionine (met) allele exhibited elevated NE when a parent had a history of depressive disorder or when relationship discord was reported by a parent. In contrast, this allele was associated with especially low NE when parental depression was absent and when the parental relationship was not discordant. Our findings suggest that the BDNF met allele confers increased child sensitivity to both positive and negative familial influences. 相似文献