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191.
The predictive power of combined neuropsychological measures for attention-deficit/hyperactivity disorder in children. 总被引:8,自引:0,他引:8
The present study explores the predictive power of seven neuropsychological assessment tools used in combination in classifying children with attention-deficit/hyperactivity disorder (ADHD). Twenty-one ADHD boys and 22 community control children participated. Group differences were significant on the continuous performance test only; however, battery analysis did increase overall predictive power, which was moderate. This study highlights the difficulty in identifying consistent mean differences on tests of frontal/executive functioning across studies, as well as the need to assess the predictive validity of these tests in classifying children with ADHD. The study suggests that these tests may provide greater predictive validity when used in combination. Inconsistencies in the literature are discussed, with consideration of research methodology, the heterogeneity of the ADHD population, and comorbid diagnoses. 相似文献
192.
Jichuan Wang Ahmmed Rahman Harvey A. Siegal James H. Fisher 《Behavior research methods》2000,32(2):357-366
Standardization and decomposition are widely used analytic techniques in population studies for adjusting the impact of compositional factors on rates. This study demonstrates the application of these methods to behavior and health studies. Bootstrapping is used to estimate standard errors of the component effects and to conduct significance tests for them. The authors have developed a Windows-based computer program that is demonstrated in the study for standardization and decomposition analysis by using empirical data on HIV seropositivity rates in two injection-drug-using populations in the northeastern United States. 相似文献
193.
Emerging evidence suggests that a traumatic brain injury (TBI) in childhood may disrupt the ability to abstract the central meaning or gist-based memory from connected language (discourse). The current study adopts a novel approach to elucidate the role of immediate and working memory processes in producing a cohesive and coherent gist-based text in the form of a summary in children with mild and severe TBI as compared to typically developing children, ages 8-14 years at test. Both TBI groups showed decreased performance on a summary production task as well as retrieval of specific content from a long narrative. Working memory on n-back tasks was also impaired in children with severe TBI, whereas immediate memory performance for recall of a simple word list in both TBI groups was comparable to controls. Interestingly, working memory, but not simple immediate memory for a word list, was significantly correlated with summarization ability and ability to recall discourse content. 相似文献
194.
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196.
Individuals with insomnia were exposed to a stressor (speech threat) prior to getting into bed and were instructed to think about the speech and its implications in either images (Image group, n = 14) or verbal thought (Verbal group, n = 17). Participants completed questionnaires about speech anxiety, arousal, and sense of resolution. Measures were taken of subjective (sleep diary estimates) and objective (actigraphy) sleep-onset latency. In the short term, the Image group reported more distress and arousal relative to those in the Verbal group. In the longer term, the Image group estimated that they fell asleep more quickly and, the following morning, reported less anxiety and more comfort about giving the speech compared with the Verbal group. 相似文献
197.
Bale HE 《Science and engineering ethics》2005,11(1):31-40
Remaining important tasks in finding and developing new drugs and vaccines for HIV/AIDS, malaria, cancer and other diseases
require continued industry research and development. Industry’s research and development pipeline has produced drugs that
have saved AIDS victims previously facing certain death, but still no cure nor vaccine is yet available. Experience with the
process of research and development indicates that it requires more than a decade of development to produce a new drug with
costs in the hundreds of millions of dollars. Intellectual property protection is critically important in assuring that drug
development continues. Partnerships between industry and the public sector have increased access to new therapies in developing
countries and promise to enhance access to both patented and generic medicines in the future.
An earlier version of this paper was presented at an international conference, “The Ethics of Intellectual Property Rights
and Patents,” held in Warsaw, Poland on 23–24 April, 2004.
This paper was prepared with the assistance of Maciej Gajewski, Policy Research Analyst, International Federation of Pharmaceutical
Manufacturers Association (IFPMA). 相似文献
198.
Koenigsberg HW Harvey PD Mitropoulou V New AS Goodman M Silverman J Serby M Schopick F Siever LJ 《Journal of personality disorders》2001,15(4):358-370
This study examines the degree to which two putative biologically influenced personality traits, affective instability and impulsive aggression, are associated with some of the interpersonal and intrapsychic disturbances of borderline personality disorder (BPD) and with choice of defense mechanism. In a sample of 152 personality disorder patients, affective instability and impulsive aggression were measured. Defense mechanisms were assessed in 140 of these patients using the Defensive Style Questionnaire (DSQ). The correlations between the traits of affective instability and impulsive aggression and the eight DSM-III-R criteria for borderline personality disorder and 20 DSQ defenses were examined. Affective instability was significantly correlated with the DSM-III-R criteria of identity disturbance, chronic emptiness or boredom, inappropriate anger, suicidality, and the affective instability criteria. It also was associated with the defenses of splitting, projection, acting out, passive aggression, undoing, and autistic fantasy. Impulsive aggression was related to unstable interpersonal relationships, inappropriate anger and impulsiveness and with the defense of acting out. It was negatively correlated with the defenses of suppression and reaction formation. A number of the interpersonal and experiential disturbances and defense mechanisms that are features of BPD are associated with the traits of affective instability and impulsive aggression among patients with personality disorders. 相似文献
199.
We used pairs of slides showing 3 women and 3 men displaying 2 sex linked carrying styles to examine differences in the attribution of homosexuality as a consequence of behavioral displays that are either sex typical or sex atypical. We hypothesized that the participants would be less likely to view targets displaying sex-typical behaviors as gay men or as lesbians. Each of 2 groups of U.S. university students rated targets in 6 slides on homosexuality and 3 other traits. The mean difference in rated homosexuality for typical versus atypical carrying styles was small but statistically significant. Thus, the results provide some empirical support for the common belief that effeminate men and masculine women are more likely to be seen as homosexual, at least by U.S. university students. 相似文献
200.
J Clevenger G M Pereira D Wiechmann N Schmitt V S Harvey 《The Journal of applied psychology》2001,86(3):410-417
Using 3 different samples, the authors assessed the incremental validity of situational judgment inventories (SJIs), relative to job knowledge, cognitive ability, job experience, and conscientiousness, in the prediction of job performance. The SJI was a valid predictor in all 3 samples and incrementally so in 2 samples. Relative to the other predictors, SJI's partial correlation with performance, controlling for the other 4 predictors, was superior in most comparisons. Subgroup differences on the SJI also appear to be less than those for cognitive ability and job knowledge, but greater than differences in conscientiousness. The SJI should prove to be a valuable additional measure in the prediction of job performance, but several additional areas of research are suggested. 相似文献