Variations in explicitly unpaired training are differentially effective in producing conditioned inhibition

To evaluate a contingency interpretation of conditioned inhibition (CI), rats were given “explicity unpaired” training in which the locus and duration of a CS within the inter-US (shock) interval were systematically manipulated for different groups. Summation and retardation tests in Experiment 1 indicated that stronger CI resulted from both a backward and a trace CS than from a midlocus CS of equal or greater duration. Complementing these findings, the same tests in Experiment 2 showed that, by comparison with novel-stimulus controls, CI developed to a trace CS but not to a mid-locus CS, nor to a trace CS that was accompanied by an immediate signal for the US. These findings argue against a contingency interpretation of CI and favor a contiguity interpretation stressing the short-term rehearsal of stimulus events. Such rehearsal of the US allows a backward CS, but not a mid-locus CS with an extended US-CS interval, to be discriminated as a signal for nonreinforcement, and thus to develop as a conditioned inhibitor. Similarly, excitatory conditioning to the memory trace of a CS allows the nominal trace CS to develop as a signal for nonreinforcement, and thus as a conditioned inhibitor, but not when its memory trace is overshadowed by another CS that immediately precedes the US. In short, the development of CI is facilitated when excitation is mediated by the memorial processing of either the US or a discrete CS for the US rather than by contextual cues.     

Centering culture in the treatment of opioid use disorder with American Indian and Alaska Native Communities: Contributions from a National Collaborative Board

American Indian/Alaska Native (AI/AN) communities are disproportionally impacted by the opioid overdose epidemic. There remains a dearth of research evaluating methods for effectively implementing treatments for opioid use disorder (OUD) within these communities. We describe proceedings from a 2-day Collaborative Board (CB) meeting tasked with developing an implementation intervention for AI/AN clinical programs to improve the delivery of medications to treat OUD (MOUD). The CB was comprised of Elders, cultural leaders, providers, individuals with lived experience with OUD, and researchers from over 25 communities, organizations, and academic institutions. Conversations were audio-recorded, transcribed, and coded by two academic researchers with interpretation oversight provided by the CB. These proceedings provided a foundation for ongoing CB work and a frame for developing the program-level implementation intervention using a strength-based and holistic model of OUD recovery and wellbeing. Topics of discussion posed to the CB included engagement and recovery strategies, integration of extended family traditions, and addressing stigma and building trust with providers and clients. Integration of traditional healing practices, ceremonies, and other cultural practices was recommended. The importance of centering AI/AN culture and involving family were highlighted as priorities for the intervention.     

Magnitude production and magnitude estimation of taste intensity

Magnitude productions of sodium chloride (salty), quinine hydrochloride (bitter), and sucrose (sweet) yielded steeper psychophysical functions than those obtained with magnitude estimation. Hydrochloric acid (sour) produced the opposite effect. The results are discussed with respect to previous findings in taste intensity scaling and to general psychophysical considerations.     

Selective mechanisms in visual perception

The notion of perceptual tuning is investigated by presenting alternatives either before, after, or both before and after a tachistoscopic stimulus. Study 1 (N = 12) showed that identification accuracy is best with alternatives both before and after the stimulus, poorest with alternatives after the stimulus, and intermediate with alternatives only before the stimulus. Study 2 (N = 3) indicated that performance with alternatives both before and after the stimulus varies according to where S is permitted to fixate prior to each exposure. The possibility of a central tuning mechanism was not strongly supported.     

The semiautomatic Wisconsin general test apparatus

A semiautomatic version of the Wisconsin General Test Apparatus is described along with circuitry. Comparison data are provided for the semiautomatic and manual WGTA obtained under comparable procedures and conditions. Response latencies are given for go/no-go object discrimination problems and subsequent retention tests.     

Discriminative and associative aspects of retroactive inhibition

Original learning of paired drawings of meaningful objects or of modified Chinese characters was followed by interpolated learning in which details of drawings were changed in one of two degrees with or without rearrangement of the original pairings. Subjects were tested for accuracy of identification of the original drawings and for associative matching of the original pairs. Identification errors were attributed jointly to confusion between original and interpolated drawings, and to unlearning of those features of original drawings which were in conflict with comparable features of interpolated drawings. Rearrangement of pairs during interpolated learning produced not only associative interference on the matching test, but also additional discriminatory interference on the identification test. Effects of associative and discriminative interference upon individual drawings were uncorrelated for meaningful material and only slightly correlated for meaningless material.     

Adolescents: A Suppressed Minority Group

The recent antagonistic but equally meritorious arguments concerning the nature of the adolescent necessitates a new framework of analysis which would incorporate these apparent antagonisms. Cursory observations indicate that more fruitful results may be obtained if the adolescent is equated to a member of a suppressed minority group. A comparison of the characteristics of the adolescent peer group to those of a suppressed minority group reveals some striking similarities.     

Relational perception and modes of perceiver operation

Judgments were made of the size of a small, luminous (inner) square appearing in the center of a somewhat larger, variable (outer) square, the whole pattern appearing in the dark. Accuracy of judgment was greatest when the outer square was constant from trial to trial but deteriorated when the outer square also varied in size, reaching a lower limit less than the accuracy produced under the absolute judgment condition (no outer square presented). An application of multiple discriminant analysis and the use of a maximum likelihood observer model provided estimates of the extent to which Os responded to inner and outer size variation as separate aspects of stimulation. Although Os differed markedly in this respect, their ability to identify inner square size under the various conditions did not reflect this difference.