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991.
Theoretical and empirical research has linked poor emotion regulation abilities with dysfunctional frontolimbic circuitry.
Consistent with this, research on borderline personality disorder (BPD) finds that frontolimbic dysfunction is a predominant
neural substrate underlying the disorder. Emotion regulation is profoundly compromised in BPD. However, BPD is also associated
with broad impairment across multiple domains, including impulse control, interpersonal relationships, and cognitive functioning.
To date, BPD research has focused largely on single areas of dysfunction, failing to account for overlap at either the biological
or behavioral levels of analysis. We examine the literature on frontolimbic dysfunction in BPD within the context of Coan’s
social baseline theory. Social baseline theory proposes that healthy human functioning is dependent upon adequate social support
and that, at baseline, biological systems are adapted to operate interdependently rather than independently. The social baseline
perspective is particularly useful for understanding borderline personality development because the impulsive and emotionally
dysregulated behaviors common among those with BPD occur almost invariably within an interpersonal context. We discuss clinical
and research implications of this work. 相似文献
992.
People often try to improve their interpersonal skills to satisfy romantic partners. However, when and why a partner appreciates these efforts is an important but underaddressed question. The present research explored how people's theories that interpersonal abilities are either fixed entities or can be changed incrementally affect their responses to relationship partner's efforts at self-improvement. Study 1 validated a new measure for these theories and showed that, compared to the former entity theorists, the latter incremental theorists were less likely to attribute recalled instances of partners' negative behaviors to dispositional causes and perceive these behaviors as fixed and stable. An experiment that induced these different implicit theories (Study 2) and a longitudinal study (Study 3) further demonstrated that perceptions of partners' self-improvement efforts led to greater increases in relationship security and quality among incremental than among entity theorists. How implicit theories may shape the interpersonal dynamics of self-improvement is discussed. 相似文献
993.
Harris JA Andrew BJ Livesey EJ 《Journal of experimental psychology. Animal behavior processes》2012,38(2):157-166
In three experiments using Pavlovian conditioning of magazine approach, rats were trained with a compound stimulus, AB, and were concurrently trained with stimulus B on its own. The reinforcement rate of B, rB, was either 1/2, 2/3, or 2/5 of rAB. After extended training, the conditioning strength of A was assessed using probe trials in which A was presented alone. Responding during A was compared with that during AB, B, and a third stimulus, C, for which rC = rAB - rB. In each experiment, the rats' response rate during A was almost identical to that during C (and during B, when rB = 1/2rAB). This suggests that, during AB conditioning, the rats had learned about rA as being equal to [rAB - rB], and implies that the content of their learning was a linear function of r. The findings provide strong support for rate-based models of conditioning (e.g., Gallistel & Gibbon, 2000). They are also consistent with the associative account of learning defined in the Rescorla and Wagner (1972) model, but only if the learning rate during reinforcement equals that during nonreinforcement. 相似文献
994.
States develop specific protocols for cystic fibrosis (CF) newborn screening to reflect the population served. We hypothesized that mutation distribution and detection rates would differ between Hispanic and non-Hispanic CF patients diagnosed by IL newborn screen with more Hispanic infants carrying mutations not detected by the state panel. Data from CF cases diagnosed via newborn screen in IL between 3/1/2008 and 10/31/2010 were reviewed. More Hispanic infants with CF had one or more undefined mutations after screening, in comparison to non-Hispanic Caucasian patients (40% vs. 9.5%; p?0.002). The risk of having a positive diagnosis of CF with only one mutation noted by positive newborn screen increases 2-fold in Hispanic Caucasian versus non-Hispanic Caucasian infants (5% vs. 2.4%). Health care providers must be aware of the limitations of CF newborn screening to ensure appropriate counseling and prompt referral for a positive newborn screen, even when zero or one mutations are identified. 相似文献
995.
Intrinsic persistent spiking mechanisms in medial entorhinal cortex (mEC) neurons may play a role in active maintenance of working memory. However, electrophysiological studies of rat mEC units have primarily focused on spatial modulation. We sought evidence of differential spike rates in the mEC in rats trained on a T-maze, cued spatial delayed response task. Animals begin at the base of the T-maze where a 1-sec white noise and visual light cue are presented on the left or right side of the maze. Rats are rewarded for responding toward the cued direction. In correct trials, we observed decreased spike rates during the delay period, the time interval between cue presentation and reward delivery. Firing-rate histograms show significant decreases during the delay period compared to 5-sec windows from both pre-cue and post-reward periods. We analyzed how running speed and trajectory specificity correlated to spike rate. Twice as many cells were responsive to cue alone compared to running speed. Trajectory specificity did not relate significantly to firing rate. Decreased spike rate may reflect active maintenance in other structures inhibiting mEC. Alternately, the reduction may reflect decreases in background activity during enhanced attention and cholinergic modulation. Lastly, animals often ran through the T-maze choice-point with varying speed. We calculated the spatial posterior probability density from spike rates during these choice-point passes. Slow passes through the choice point were characterized by greater probability of decoding to the reward locations on correct trials compared to quick passes on the maze consistent with similar "look-ahead" properties previously reported in the hippocampus and ventral striatum. 相似文献
996.
Previous research has established that infants are unable to perceive causality until 6¼ months of age. The current experiments examined whether infants’ ability to engage in causal action could facilitate causal perception prior to this age. In Experiment 1, 4½‐month‐olds were randomly assigned to engage in causal action experience via Velcro sticky mittens or not engage in causal action because they wore non‐sticky mittens. Both groups were then tested in the visual habituation paradigm to assess their causal perception. Infants who engaged in causal action – but not those without this causal action experience – perceived the habituation events as causal. Experiment 2 used a similar design to establish that 4½‐month‐olds are unable to generalize their own causal action to causality observed in dissimilar objects. These data are the first to demonstrate that infants under 6 months of age can perceive causality, and have implications for the mechanisms underlying the development of causal perception. 相似文献
997.
This experiment examined the performance of common marmosets (Callithrix jacchus) on a series of patterned string problems to assess the marmosets’ understanding of means–ends relationships. One marmoset, Jet, was exposed to a series of problems that were ordered in terms of perceived difficulty during two testings that were separated by 1 year. In the second testing, Jet received problems that had been used during the first testing along with three new problems. Each of the new problems was designed to be an exemplar of the type of problem that Jet had experienced difficulty with in the first testing. A second marmoset, Peaches, was tested on the same set of problems given to Jet in the second testing. Results indicated that the marmosets’ performance on these problems fell into three categories. In one category, some problems were solved without evidence of trial-and-error learning. In a second category, there were problems in which the marmosets responded at chance levels initially but evidenced improvement as a function of extended testing. In a third category, some problems appeared to be virtually unsolvable even with extended testing. Taken together, these results indicate that the marmosets were able to learn the means–ends connection between pulling a string and obtaining food. This learning was best characterized as a trial-and-error process for some problem forms, while for others there appeared to be rapid learning that did not require extensive practice. The instances of rapid learning may be the result of the application of a simple spatial proximity rule in which the marmosets chose the string that was closest to an imaginary line drawn between the marmoset and the reinforcer. 相似文献
998.
Research has shown that those with insomnia focus primarily on their sleep as a cause of daytime fatigue rather than the multitude of other possible causes of fatigue. This can create sleep-related anxiety and further perpetuate the sleep disturbance. In order to lessen the increased focus on sleep, the present study investigated whether people could learn to consider other attributions for fatigue via an information-based manipulation. Undergraduate students (N = 88) were randomized to two information groups: They either received information about common factors that could explain daytime fatigue (the fatigue information condition) or received generic sleep-related information (the control condition). Each group was tested pre- and post-intervention. Fatigue information participants were significantly more likely to consider non-sleep-related attributions for fatigue at post-intervention, relative to control participants. These results demonstrate that attributions for fatigue may be amenable to change via an information-based intervention; thus, this research explores a preliminary step toward investigating refinements to insomnia treatments. 相似文献
999.
Berryhill ME Richmond LL Shay CS Olson IR 《Quarterly journal of experimental psychology (2006)》2012,65(3):426-438
It is well known that visual working memory (VWM) performance is modulated by attentional cues presented during encoding. Interestingly, retrospective cues presented after encoding, but prior to the test phase also improve performance. This improvement in performance is termed the retro-cue benefit. We investigated whether the retro-cue benefit is sensitive to cue type, whether participants were aware of their improvement in performance due to the retro-cue, and whether the effect was under strategic control. Experiment 1 compared the potential cueing benefits of abrupt onset retro-cues relying on bottom-up attention, number retro-cues relying on top-down attention, and arrow retro-cues, relying on a mixture of both. We found a significant retro-cue effect only for arrow retro-cues. In Experiment 2, we tested participants' awareness of their use of the informative retro-cue and found that they were aware of their improved performance. In Experiment 3, we asked whether participants have strategic control over the retro-cue. The retro-cue was difficult to ignore, suggesting that strategic control is low. The retro-cue effect appears to be within conscious awareness but not under full strategic control. 相似文献
1000.