Cognitive impairment and whole brain diffusion in patients with neuromyelitis optica after acute relapse

The objective of this study investigated cognitive impairments and their correlations with fractional anisotropy (FA) and mean diffusivity (MD) in patients with neuromyelitis optica (NMO) without visible lesions on conventional brain MRI during acute relapse. Twenty one patients with NMO and 21 normal control subjects received several cognitive tests to assess cognitive function. Head diffusion tensor imaging (DTI) of all patients with NMO were collected with a 3-T MR system. Correlations of cognitive test scores and whole brain FA and MD were examined by voxel-based analysis. Region-of-interest analysis was applied to the significantly correlated regions which the most frequently appeared. We found that NMO patients without visible brain lesions had significantly impaired learning and memory, decreased information processing speed, and damaged attention compared with normal control subjects. These impaired cognitive domains were significantly correlated with FA and MD in local regions of corpus callosum, anterior cingulate and medial frontal cortex. In corpus callosum of NMO patients, mean FA was significantly lower and mean MD higher than normal control subjects. Our findings suggest that cognitive impairments in learning and memory, information processing speed and attention occur in NMO patients without visible brain lesions during acute relapse. The impairments in immediate and short-term memory in NMO patients may be due to information encoding deficits in the process of information acquisition. The corpus callosum of such patients may have local microscopic damages that play a role in cognitive impairments during acute relapse.     

行为免疫系统对个体就医行为倾向的影响

研究首次考察了行为免疫系统与个体就医行为倾向的关系。3个研究一致显示：行为免疫系统特质性激活水平较高的个体更容易对就医持消极态度和延迟就医; 情境性激活行为免疫系统会使得个体更不愿意就医和更倾向于延迟就医; 且行为免疫系统激活对就医态度和就医延迟倾向的影响以对就医感染风险的感知为中介。这支持了进化失配假说, 提示行为免疫系统对现代医学可能缺乏进化的适应性, 并为理解现代人类就医行为提供了新的理论视角。     

Parental Psychological Control and Adolescents’ Problematic Mobile Phone Use: The Serial Mediation of Basic Psychological Need Experiences and Negative Affect

Journal of Child and Family Studies - Drawing on self-determination theory and problem-behavior theory, we tested the relation between parental psychological control and adolescents’...     

The Sex-Based Harassment Inventory: A Gender Status Threat Measure of Sex-Based Harassment Intentions

Sex Roles - We introduce a new inventory measuring sex-based harassment intentions and threat perceptions grounded in gender status threat theories (Berdahl, 2007; Stephan et al., 2016). In Study 1...     

基于作答时间数据的改变点分析在检测加速作答中的探索——已知和未知项目参数

相对于传统的离散作答数据, 作答时间作为连续数据, 可以提供更多信息。改变点分析(change point analysis)技术在心理和教育领域是一个比较新的技术。本文一方面对改变点分析在心理测量领域的应用进行了一个综合的总结和分析; 另一方面, 将基于作答数据的两种改变点分析统计量推广到作答时间数据, 将改变点分析技术应用到测验异常作答模式：加速作答speededness的检测上。采用两种检验方法：似然比检验和Wald检验, 分别在已知和未知项目参数的条件下, 实现异常作答模式的检测。结果表明, 所采用的方法对于加速作答行为的检测具有很高的检验力, 同时能够很好的控制I类错误率。实证数据分析进一步表明本文中所使用的方法具有应用价值。     

Do Teachers maintain their Expectation Bias for students? A longitudinal investigation

Whether teachers maintain their expectation bias for students over time is crucial for understanding self-fulfilling prophecy effects. However, the stability of teacher expectation bias has been largely ignored in the literature. We examined the stability of teacher expectation bias across a sample of teachers and the change trajectories of teacher expectation bias across high-, medium-, and low-expectation teacher groups across all teachers and in the curriculum areas of mathematics, Chinese, and English. Our analyses were based on two-year longitudinal data with four time points from 567 Chinese senior high school students and their 50 teachers. The results showed that across all teachers, teacher expectation bias at the individual student level was dynamic over time. That is, teachers seemed to adjust their initial expectation bias in the first few months but then maintained the adjusted expectation bias afterwards. However, when students moved from Grade 11 to Grade 12 (the last year of high school), teachers seemed to change their expectation bias again. The evidence from HLM analyses further supported these results. That is, all the high- and low-expectation teachers alleviated their initial expectation bias significantly in the first six months and then adhered to their adjusted expectation bias. However, when students moved to the last year of high school, some high- and low-expectation teachers’ expectation biases were volatile again. Nevertheless, most high- and low-expectation teachers (except for Chinese low-expectation teachers) tended to either over-estimate or under-estimate their students across two school years. Further, compared to Chinese and mathematics teachers, English teachers’ biases seemed to be even more stable. Our findings suggested that some teachers consistently over- or under-estimated their students over an extended time period and this could have implications for student outcomes.

     

Mental Disorders Associated with COVID-19 Related Unemployment

In response to the COVID-19 pandemic, restrictions on economic activities have resulted in a sharp rise of unemployment. The purpose of this research is to explore mental disorders associated with COVID-19 related unemployment using a large, nationally representative dataset, the 2020 COVID-19 Household Pulse Survey. ANOVA with post hoc tests (Tukey HSD) are utilized to reveal the mean difference of mental disorders between various employment status, as well as between reasons of unemployment. Binary logit model is used to investigate the potential effect of different reasons of unemployment on mental disorders. Individuals who were not working during the pandemic due to involuntary reasons had higher probabilities of mental disorders than those who were working and those who voluntarily separated from work. Among respondents who were not working due to COVID-19 related reasons, respondents whose employer went out of business were the most likely to experience mental disorders. Household job uncertainty in the next four weeks positively contributed to mental disorders. Government should consider measures to contain the spread of virous while keeping as many people employed as possible. Government should also consider providing adequate financial and counseling assistance to individuals who are in the greatest need for such support.

     

“It is not a something,but not a nothing either!”—McDowell on Wittgenstein

This paper corrects a mistake in John McDowell’s influential reading of Wittgenstein’s attack on the idea of private sensations. McDowell rightly identifies a primary target of Wittgenstein’s attack to be the Myth of the Given. But he also suggests that Wittgenstein, in the ferocity of his battles with this myth, sometimes goes into overkill, which manifests itself in seemingly behavioristic denials about sensations. But this criticism of Wittgenstein is a mistake. The mistake is made over two important but notoriously difficult sections in the so-called Private Language Argument, namely §304 and §293 of the Philosophical Investigations. Wittgenstein, maximally charitably read, commits no overkill in these two sections. This correction strengthens McDowell’s overall reading, but it is only a first step toward fully bringing out the deep but obscurely expressed insights in §304 and §293, the full treatment of which must await another occasion.     

多级评分模型下的题库结构对CAT的影响分析

在多级评分模型下,项目的难度参数或步骤参数有多个,在对多级评分模型进行选题时,通常对项目的多个难度参数用一个综合的指标来概括.当对每个项目的难度参数进行有效的综合后,综合后的难度参数分布发生了改变,这时如果增加适量的平均难度较难或较易的项目进入题库,测验的精度和项目的曝光率都有一定的改善.     

The dermatology life quality index (DLQI) and the hospital anxiety and depression (HADS) in Chinese rosacea patients

The study aims to investigate the quality of life (QOL) and the psychological situation in Chinese patients with rosacea. A total of 196 healthy controls and 201 rosacea patients were involved in the final analysis. The general information, the Dermatology Life Quality Index (DLQI) and the Hospital Anxiety and Depression Scale (HADS) were collected. Significantly higher DLQI, anxiety and depression score were observed in the rosacea group compared to the control group (p < .01). Total DLQI score of patients was positively related with anxiety (r = .526, p < .001) and depression scores (r = .399, p < .001) in HADS. Rosacea had significant psychological impact on Chinese patients and had substantial influence on their QOL. Physicians should address the psychosocial needs of rosacea patients as much as its physical symptoms.