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851.
Van Steendam G Dinnyés A Mallet J Meloni R Casabona CR González JG Kure J Szathmáry E Vorstenbosch J Molnár P Edbrooke D Sándor J Oberfrank F Cole-Turner R Hargittai I Littig B Ladikas M Mordini E Roosendaal HE Salvi M Gulyás B Malpede D 《Science and engineering ethics》2006,12(4):731-793
This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6-9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy. Discussions during The Budapest Meeting are reported in depth in this paper as well as the initiatives to involve the participating groups and others in ongoing collaborations with the goal of forming an integrated network of European resources in the fields of ethics of science. 相似文献
852.
Postural control in otolith disorders 总被引:1,自引:0,他引:1
It was the aim of the present paper to investigate the influence of otolith disorders on human postural control by different methods. The 33 patients of our study had undergone a minor head injury and suffered subsequently from an utricular or sacculo-utricular disorder as evidenced by vestibular evoked myogenic potential recordings and eccentric rotation recordings of the otolith-ocular responses. Postural control was assessed by performing stance/gait tests (standard balance deficit test, SBDT) and by evaluating trunk sway (using angular velocity sensors). Moreover, classical tests of the posterior column of the spinal tract (Romberg/Unterberger) and the dynamic posturography (sensory organization test, SOT) were included. It could be shown that SBDT tasks with reduced proprioceptive and visual cues (e.g. standing on foam, eyes closed) are most sensitive for an otolith disorder. The patients showed an increased trunk sway in the pitch plane (i.e. linear motion as adequate utricular stimulus) and an increase in sway velocities (i.e. tilting movements as adequate saccular stimulus) compared to controls. The SOT was most sensitive for combined (sacculo-utricular) otolith disorders (78%) while vestibulospinal tests are not enough sensitive. In essence, otolith disorders evidently impair human postural control and have been possibly underestimated as a source of posttraumatic postural imbalance as yet. 相似文献
853.
Hans Lenk 《Man and World》1970,3(1):16-25
Ohne Zusammenfassung 相似文献
854.
In recent years there has been a growing consensus that ordinary reasoning does not conform to the laws of classical logic,
but is rather nonmonotonic in the sense that conclusions previously drawn may well be removed upon acquiring further information.
Even so, rational belief formation has up to now been modelled as conforming to some fundamental principles that are classically
valid. The counterexample described in this paper suggests that a number of the most cherished of these principles should
not be regarded as valid for commonsense reasoning. An explanation of this puzzling failure is given, arguing that a problem
in the theory of rational choice transfers to the realm of belief formation. 相似文献
855.
Visuo-spatial working memory span: a sensitive measure of cognitive deficits in children with ADHD. 总被引:1,自引:0,他引:1
Helena Westerberg Tatja Hirvikoski Hans Forssberg Torkel Klingberg 《Child neuropsychology》2004,10(3):155-161
Working memory (WM) has been hypothesised to be impaired in attention-deficit/hyperactivity disorder (ADHD). However, there are few studies reported on tests measuring visuo-spatial WM (VSWM) in ADHD. Some of these studies used paradigms including episodic memory, others only used low memory loads. In the present study we used a VSWM test that has not been used previously in ADHD research. The sensitivity of the VSWM test and a choice reaction time (CRT) test was evaluated in a pilot study by comparing them to two commonly used tests in ADHD-research; the Continuous Performance Test (CPT) and a Go/no-go test, in children with and without ADHD. The groups differed significantly in performance on the VSWM test (P < .01) and CRT (P < .05) but not on the CPT (P > .1) or on the Go/no-go test (P > .1). The results from the VSWM and CRT tests were replicated in a larger sample of participants (80 boys; 27 boys with ADHD and 53 controls, mean age 11.4 years). The difference between the groups was significant for both the VSWM test (P < .01) and the CRT test (P < .01). The effect size (ES) of the VSWM test was 1.34. There was a significant age-by-group interaction on the VSWM test, with larger group differences for the older children (P < .01). Our results show that the VSWM test is a sensitive measure of cognitive deficits in ADHD and it supports the hypothesis that deficits in VSWM is a major component of ADHD. 相似文献
856.
In the present study, a new hypothesis on the neural mechanisms linking affect to attention was brought forward by evolutionary
simulations on agents navigating a virtual environment while collecting food and avoiding predation. The connection strengths
between nodes in the networks controlling the agents were subjected to random variation, and the fittest agents were selected
for reproduction. Unexpectedly, oscillations of node activations emerged, which drastically enhanced the agent’s fitness.
We analyzed the mechanisms involved in the modulation of attention and found that oscillations acted on competitive networks.
Response selection depended on the connection structure, but the speed and efficacy of switching between selections was modulated
by oscillation frequency. The main focus of the present study was the differential emergence of stimulus-specific oscillation
frequencies. Oscillations had a higher frequency in an appetitive motivational state than in an aversive state. We suggest
that oscillations in biological networks also mediate the affective modulation of attention. 相似文献
857.
When reviewing the non‐European perspectives of Lutheran theology presented in the contributions of this issue of Dialog, it is easy to recognize a dominant, unifying theme and a common task in a confrontation with the new Pentecostal churches. It then makes sense to refer to the two central themes and tasks of Lutheran theology mentioned in this volume: the development of a Lutheran pneumatology in contrast to the Pentecostal/charismatic movements; and an interpretation of the Lutheran doctrine of justification that concentrates on how the pure grace and love of God can be witnessed in good works. As a future focal point of Lutheran theology, the contributions from non‐European Lutheran Christianity presented here show that the connection between the theology of the cross as a central element of the grammar of Lutheran Christianity and the dialectics of law and gospel for the interpretation of the salutary efficacy and experienceable nature of the Spirit requires further reflection. 相似文献
858.
An extraordinary physiological capacity combined with remarkable motor control, perception, and cognitive functioning is crucial for high performance in sports. Tests that assess the physical abilities are already well established. Moreover, a growing area of research evolved in the recent past that is particularly concerned with the basic cognitive functions by means of neurocognitive tests in experts and elite athletes. The aim of this meta‐analysis (k = 19) is to quantify differences among experts and nonexperts as well as elite athletes and non‐elite athletes. In addition, it aims to assemble and compare previous research and analyze possible differences in cognitive functions depending on age, skill level, and used cognitive tasks. Overall, the mean effect size was small to medium (r = 0.22), indicating superior cognitive functions in experts and elite athletes. The factor of skill definition significantly differentiates the cognition–expertise relationship. In contrast, differences in age groups and cognitive areas appeared but were not significant. Future research should prefer the elite rather than the expert definition and distinguish between high‐performance and amateur athletes. Furthermore, the findings suggest that it can be beneficial for coaches and sport clubs to integrate cognitive tests as an additional tool for scouting and for optimizing the athletic development of their players. 相似文献
859.
Johanna Stålnacke Aiko Lundequist Birgitta Böhm Hans Forssberg Ann-Charlotte Smedler 《Child neuropsychology》2019,25(3):318-335
Executive function deficits are often reported as a specific weakness in preterm children. Yet, executive function development is still not fully understood. In a prospective longitudinal study, 115 preterm born children, ≤31 weeks of gestation, were recruited at birth and subject to neuropsychological assessments at ages 5.5 and 18 years. By applying Miyake and colleagues’ integrative framework of executive function to our data, two core components of executive function, working memory and cognitive flexibility, were identified through confirmatory factor analysis. Developmental stability was investigated in a serial multiple mediator structural equation model. Biological, medical, and social factors as well as mental development at 10 months were entered as predictors. Both components of executive function were highly stable from 5.5 to 18 years. Gestational age, intrauterine growth, lack of perinatal medical complications, and female sex were positively related to mental development at 10 months, which together with parental education influenced both core executive functions at 5.5 years. Working memory at 5.5 years mediated outcome in working memory at 18 years. In addition to the mediation of cognitive flexibility at 5.5 years, perinatal medical complications and restricted intrauterine growth had a continued direct negative impact on cognitive flexibility at 18 years. The application of a theoretical framework added to our understanding of executive function development in preterm born children. The study supports early identification of executive deficits among children born preterm, as deficits are unlikely to diminish with maturation. 相似文献
860.
The research on commons dilemmas is characterized by innumerable published findings, each standing relatively isolated from the other. To date there is little integration of the findings under a unified concept. The present contribution aims to integrate already existing findings in a general dynamic model of cooperative behavior in resource crises by means of computer simulation. The model postulates that people base their decisions regarding resource use on both ecological and social information. Whether or not ecological or social information will dominate, however, depends on people's social values, attributions, and their perceptions of the state of the resource. The advantage of the simulation method used is that successful integration of the findings can be shown explicitly, as the simulation then replicates the experimental data. With the model presented here, it is also possible to let variables work together whose interaction has not yet been investigated in real experiments. For instance, the simulation model allows us to hypothesize that people, in dependency upon their resource uncertainty and in dependency upon their attributions, utilize a resource completely differently if the resource is in an optimal or sub‐optimal condition. Copyright © 2002 John Wiley & Sons, Ltd. 相似文献