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The authors investigated the relationship between stress at initial cancer diagnosis and treatment and subsequent quality of life (QoL). Women (n = 112) randomized to the assessment-only arm of a clinical trial were initially assessed after breast cancer diagnosis and surgery and then reassessed at 4 months (during adjuvant treatment) and 12 months (postadjuvant treatment). There were 3 types of stress measured: number of stressful life events (K. A. Matthews et al., 1997), cancer-related traumatic stress symptoms (M. J. Horowitz, N. Wilner, & W. Alvarez, 1979), and perceived global stress (S. Cohen, T. Kamarck, & R. Mermelstein, 1983). Using hierarchical multiple regressions, the authors found that stress predicted both psychological and physical QoL (J. E. Ware, K. K. Snow, & M. Kosinski, 2000) at the follow-ups (all ps < .03). These findings substantiate the relationship between initial stress and later QoL and underscore the need for timely psychological intervention.  相似文献   
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This article analyzes the way a series of recent policy statements have been used to promote and shape the take-up of e-commerce in Denmark. Issuing periodic policy statements, with a combination of direct and indirect modes of intervention, is one of the roads governments are taking to influence the evolutions of ICT. The policy statements present the goals, launch initiatives, and assess achievements. Complementing a co-or self-regulation strategy, the policy statement approach has become particularly important in areas where governments seek to influence the take-up of a technology without appearing to tip the scales. She did her Ph.D. at the Center for Electronic Commerce, at Department of Informatics, Copenhagen Business School. Helle Zinner Henriksen has a degree in Law (University of Copenhagen, 1995). Her research interests include: Adoption and diffusion of Interorganizational Information Systems, e-government, and institutional regulation of electronic commerce and e-government. Kim Viborg Andersen is a researcher in organizational and policy aspects of IT. Andersen’s research encompasses various applications: economic models, EIS/BIS, health data network, EDI, e-commerce, and mobile applications primarily within the public sector domain. He is co-founder of the AIS SIG on e-government, vice-chair of the IFIP WG 8.4 on interdisciplinary e-business and on various editorial boards for journals. He is head of the Center for Research on Information Technology in Policy Settings (CIPS) at the Copenhagen Business School.  相似文献   
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The field of nanoscience and nanotechnology is expanding rapidly, promising great benefits for society in the form of better medicine, more efficient energy production, new types of materials, etc. Naturally, in order for the science and technology to live up to these promises, it is important to continue scientific research and development, but equally important is the ethical dimension. Giving attention to the social, ethical and legal aspects of the field, among others, will help in developing a fully responsible—and thereby capable—science and technology. Nanoethics has emerged as a field concerned with such ethical issues related to nanoscience and nanotechnology. Even though this field is relatively new, a significant amount of literature has already been published. This paper focuses on three of the major issues which are discussed in the literature of nanoethics, and also points to a certain bias in this literature. Each quite different in nature, these issues are: (1) The naming and (2) the timing of and approach to the field, as well as (3) the issue of safety. As will be seen, these issues are almost exclusively discussed by ethicists, (throughout the article, the term’ethicist’ is used in a broad definition covering philosophers, social and political scientists as well as philosophers of science) thus having no direct influence on the work being carried out by scientists. One can argue, therefore, that this bias creates a distortion of the ethical debate, making it insufficient and misleading. Ultimately, this bias is caused by the lack of communication and collaboration between ethicists on the one hand, and nanoscientists on the other. Thus, an argument is made for the different disciplines to begin collaborating, so as to more effectively and responsibly develop the field of nanoscience.  相似文献   
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The effects of eating on heart rate variability (HRV) differ between adults and newborns. This may reflect the impact of suckling on the overall psychophysiological and autonomic nervous system maturation. The purpose of the present study was to explore whether the reactions of HRV during feeding change towards the adult pattern during the first 6 months of life. In addition, the effects of non-nutritive and nutritive sucking on heart rate (HR) and HRV were compared. The participants were 23 infants on whom recordings were performed as newborns and at 6, 12 and 24 weeks old. Nutritive sucking caused an increase in HR and a decline in HRV. The results were consistent with previous reports of a decrease in high frequency components of HRV during feeding in newborns, reflecting a decrease in parasympathetic activity. This response was apparent in all four ages studied, and remained similar throughout the 6-month period. However, age as an independent factor seemed to influence both HR and HRV. Pacifier sucking had no significant effects on HRV at any age. The results demonstrate the physical strain that sucking imposes on the baby, with a specific autonomic nervous system response involved. We consider this response an essential part of the overall psychophysiological maturation of infants.  相似文献   
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Most Norwegians are Internet users. We conducted a stratified probability sample study (Norway, 2007, age-group 16–74 years, N = 3,399, response rate 35.3%, 87.1% Internet users) to assess the prevalence of Internet addiction and at-risk Internet use by the Young Diagnostic Questionnaire (YDQ). The prevalence of Internet addiction (YDQ score 5–8) was 1.0% and an additional 5.2% were at-risk Internet users (YDQ score 3–4). Internet addiction and at-risk Internet use was strongly dependent on gender and age with highest prevalences among young males (16–29 years 4.1% and 19.0%, 30–39 years 3.3% and 10.7%). Logistic regression showed that male gender, young age, university level education, and an unsatisfactory financial situation were factors positively associated with "problematic Internet use" (at-risk and addicted use combined). Time spent on the Internet and prevalence of self-reported sleeping disorders, depression, and other psychological impairments increased linearly with YDQ score. Problematic Internet use clearly affects the lives of many people.  相似文献   
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The present study investigated the brain mechanisms involved during young children's receptive familiarization with new words, and whether the dynamics of these mechanisms are related to the child's productive vocabulary size. To this end, we recorded event-related potentials (ERPs) from 20-month-old children in a pseudoword repetition task. Results revealed distinct patterns of repetition effects for children with large and small productive vocabularies. High producers showed evidence of recognizing the novel words already after three presentations, while the low producers needed five presentations to display a recognition effect. The familiarization process was manifested in the modulations of two components, the N200-400 and a later fronto-central component, which appeared to increase in amplitude until a certain level of encoding was reached and then decrease with further repetition. These findings suggest a relation between the onset of the productive vocabulary spurt and the rate of receptive word familiarization.  相似文献   
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A considerable body of empirical and theoretical research suggests that morphological structure governs the representation of words in memory and that many words are decomposed into morphological components in processing. The authors investigated an alternative approach in which morphology arises from the interaction of semantic and phonological codes. A series of cross-modal lexical decision experiments shows that the magnitude of priming reflects the degree of semantic and phonological overlap between words. Crucially, moderately similar items produce intermediate facilitation (e.g., lately-late). This pattern is observed for word pairs exhibiting different types of morphological relationships, including suffixed-stem (e.g., teacher-teach), suffixed-suffixed (e.g., saintly-sainthood), and prefixed-stem pairs (preheat-heat). The results can be understood in terms of connectionist models that use distributed representations rather than discrete morphemes.  相似文献   
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