Phosphorylation of mitogen-activated protein kinase in the medial prefrontal cortex and the amygdala following memory retrieval or forgetting in developing rats

We examined neuronal correlates of forgetting in rats by detection of phosphorylated mitogen-activated protein kinase (pMAPK) in the medial prefrontal cortex (mPFC) and amygdala. In Experiment 1, postnatal day (P)23 and P16 rats received paired noise CS-shock US presentations. When tested immediately after conditioning, P23 and P16 rats exhibited similar levels of conditioned fear; when tested after 2 days, however, P16 rats showed poor CS-elicited freezing relative to P23 rats. In Experiment 2, P16 and P23 rats received either paired or unpaired CS-US presentations, and then were tested 48 h later. Consistent with Experiment 1, P16 rats showed forgetting whereas P23 rats exhibited good retention at test. Additionally, unpaired groups showed poor CS-elicited freezing at test. Immunohistochemistry showed that P23 and P16 rats given paired presentations exhibited significant elevation of pMAPK-immunoreactive (ir) neurons in the amygdala compared to rats given unpaired presentations. That is, MAPK phosphorylation in the amygdala tracked learning history rather than behavioral performance at test. In contrast, only the P23-paired group showed an elevated number of pMAPK-ir neurons in mPFC, indicating that MAPK phosphorylation in the mPFC tracks memory expression. Different test-perfusion intervals were employed in Experiment 3, which showed that the developmental dissociation in the pMAPK-ir neurons observed in the mPFC in Experiment 2 was not due to age differences in the rate of phosphorylation of MAPK. These findings provide initial evidence suggesting that while the mPFC is involved in memory retrieval, MAPK phosphorylation in the amygdala may be a persisting neural signature of fear memory.     

Temporal factors in visual perception as related to aging

Older Ss, in the age range 30–55 years, were compared on certain temporal characteristics of visual perception. Experiment I confirmed a previous finding that older adults required an appreciably longer exposure duration to identify forms, even when equated with younger adults on standard measures of visual acuity. Experiment 2 found that older adults have a longer critical duration over which time-intensity reciprocity holds for form identification. The results were discussed in terms of such concepts of psychological time as the psychological moment.     

What about the Male Victims? Exploring the Impact of Gender Stereotyping on Implicit Attitudes and Behavioural Intentions Associated with Intimate Partner Violence

Sex Roles - Past research has indicated that women who work in male-dominated fields, such as politics, face discrimination due to a stereotypically perceived poor fit between their gender and...     

The mentalistic basis of core social cognition: experiments in preverbal infants and a computational model

Evaluating individuals based on their pro‐ and anti‐social behaviors is fundamental to successful human interaction. Recent research suggests that even preverbal infants engage in social evaluation; however, it remains an open question whether infants’ judgments are driven uniquely by an analysis of the mental states that motivate others’ helpful and unhelpful actions, or whether non‐mentalistic inferences are at play. Here we present evidence from 10‐month‐olds, motivated and supported by a Bayesian computational model, for mentalistic social evaluation in the first year of life.A video abstract of this article can be viewed at http://youtu.be/rD_Ry5oqCYE     

Negative affect and interpersonal rejection among prison inmates in a therapeutic community: a social relations analysis.

The authors used D. A. Kenny's social relations model to examine J. C. Coyne's interpersonal theory of depression among a clinical sample of well-acquainted prison inmates. Members of 12 therapy groups (N = 142) diagnosed with a substance abuse disorder completed a self-report measure of depression and anxiety and indicated their desire to interact with other group members. There was both consensus about which group members were rejected and individual differences in the participants reported desire for future interaction with other group members. Those reporting high levels of depressive negative affect were most likely to be rejected. Those lowest in positive affect indicated the least desire for future interaction with others.