The ontogeny of hemispheric specialization: some old hypotheses revisited

This paper re-examines two hypotheses on the ontogeny of hemispheric specialization that long ago fell into disfavor in neuropsychology. It is argued that these hypotheses, equipotentiality and progressive lateralization, may have suffered from misinterpretation that fostered premature acceptance of the developmental invariance view of hemispheric specialization. An alternative view is presented that incorporates both hypotheses within a neurodevelopmental context using anatomical (postmortem) and childhood aphasia data.     

Benzodiazepine receptor ligand influences on acquisition: suggestion of an endogenous modulatory mechanism mediated by benzodiazepine receptors

In rats, pretraining ip administration of the central benzodiazepine receptor antagonist, flumazenil (5.0 mg/kg), or of the inverse agonist, n-butyl-beta-carboline-3-carboxylate (BCCB) (0.2 or 0.5 mg/kg), facilitated retention of a step-down inhibitory avoidance task; the central agonists, clonazepam and diazepam (0.4 or 1.0 mg/kg), had an opposite effect, and the peripheral agonist, 4'-chlordiazepam (1.25 or 6.25 mg/kg), was without effect. Pre- but not post-training flumazenil (2.0 mg/kg) blocked the effect of BCCB (0.5 mg/kg), clonazepam (1.0 mg/kg), or diazepam (1.0 mg/kg) given also pretraining. The post-training administration of all of these drugs had no effect on retention of the avoidance task. Flumazenil (5.0 mg/kg) and BCCB (0.5 mg/kg), given before training, enhanced retention test performance of habituation to a buzzer but not of habituation to an open field. In the three tasks studied, none of the drugs used had any appreciable effect on training session parameters. These results suggest that there is an endogenous mechanism mediated by benzodiazepine agonists, sensitive to inverse agonists, that normally down-regulates acquisition of certain behaviors; this mechanism becomes activated only when the tasks involve or occur with a certain degree of stress or anxiety (i.e., inhibitory avoidance or habituation to the buzzer) and not in less stressful or anxiogenic tasks (i.e., habituation to an open field).     

Values and Recovery From Alcoholism Through Alcoholics Anonymous

This report reviews the literature on the values of alcoholics and addicts in treatment and presents data that suggest a shift in values is involved in recovery from alcoholism through participation in Alcoholics Anonymous and that values clarification and value therapy may be useful in chemical dependency treatment.     

Testosterone and personality among college students and military veterans

Relationships of serum and saliva to personality were examined among 401 college students in four laboratory studies and 5,236 military veterans in one archival study. Among the students, there were few relationships between testosterone and traditional personality measures. Among the veterans, MMPI scores and DSM-III diagnoses showed testosterone related to drug and alcohol abuse, antisocial and generally intemperate behavior, and effective disorders. Consistent with social control theory, correlations were higher among veterans who were lower in socioeconomic status. It appears likely that testosterone has innate effects that are socially undesirable but can be attenuated by bonds between the individual and society. Effect sizes were small, suggesting that testosterone will have noticeable effects only in large populations or individuals who differ markedly from the population mean. Further research should focus upon antisocial correlates of testosterone and conditions that produce marked changes in testosterone levels.     

Tracks and affordances: The sources of a physical ontology

How is meaning assigned to those terms in a theory which are remote from direct observational instantiation? Models and analogies play a role, but close examination of theories in high energy physics shows that the design of experimental apparatus also influences the interpretation of such terms. Certain apparatus favours certain kinds of effects, and this affects the way mathematical theories are interpreted. In particular track producing apparatus becomes involved with theories in which photonic terms are picked out in the theory. A further conceptual constraint is thus introduced. It is argued that this situation favours the interpretation of dispositional properties as affordances rather than as simple dispositions.     

Laws,chances and properties

The paper develops a unified account of both deterministic and indeterministic laws of nature which inherits the merits but not the defects of the best existing accounts. As in Armstrong's account, laws are embodied in facts about universals; but not in higher‐order relations between them, and the necessity of laws is not primitive but results from their containing chances of 0 or 1. As in the Ramsey‐Lewis account, law statements would be the general axioms and theorems of the simplest deductive theory of everything; but because laws are not so defined, simplicity of statement is not a criterion of law‐hood.     

The role accorded to the public by philosophers of science 1

The role accorded to the public by scientists and philosophers of science has undergone an essential historical change in the last three centuries. Public participation in (witnessing of) scientific experiments was considered an important requirement for 17th century experimenters (e.g. for Boyle or Pascal). The cognitive role played by lay persons was later substantially downgraded; witnessing went out of fashion, while science became more and more esoteric and a matter for experts only. Part of this process was that all scientific disciplines became intensively compartmentalized and in consequence a rather puzzling or even paradoxical situation appeared: that the scientists themselves were and are being reduced epistemically to the status of lay persons, outside of their proper field of expertise (as was pointed out by J. Hardwig). The paper deals with some cognitive aspects of this historical process.     

Efficacy of behavioral management and patient education on vascular access cleansing compliance in hemodialysis patients

Compared four treatment conditions to test their ability to enhance compliance with vascular access cleansing (VAC) procedures in a group of 56 hemodialysis patients. The conditions were patient education, behavioral management with monetary incentive, patient education/behavioral management, and attention control. Behavioral observers rated VAC behavior at pretreatment, posttreatment 1-month follow-up, and 1-year follow-up. Knowledge of VAC procedures was also assessed via a questionnaire at pretreatment and posttreatment. Data were analyzed using repeated-measures multivariate analyses of variance. Results indicated that the patients in the education/behavioral, behavioral, and education groups gave significantly more correct answers on our VAC knowledge questionnaires at posttreatment than did patients in the attention control group. Further, patients in the education/behavioral and behavioral groups completed significantly more VAC steps at posttreatment and 1-month follow-up than did patients in the education group and in the attention control group. Differences were not maintained at 1-year follow-up, although more than 50% of the patients were lost to follow-up. Implications of the present findings for behavioral and educational interventions are discussed.     

How far can attraction-caused misalignment account for the Morinaga misalignment effect?

Summary When a line (the pointer) is collinear with a dot, the addition of a second line (the induction line) contiguous with the dot or near it may cause the pointer to appear to be collinear with a point further along or nearer to the induction line. The geometrical relations upon which this effect, which we call attraction-caused misalignment, depends have been studied with the Obonai and Wundt-Loeb (Hotopf, 1981; Hotopf & Brown, 1988) figures. Drawing upon the studies of misalignment in the Morinaga figure carried out by Restle (1976), Day, Bellamy, and Norman (1983), and Day and Kasperczyk (1985), as well as upon two new experiments, we show that misalignment in the Morinaga figure is also attraction-caused misalignment, as previously defined. We conclude with a discussion of a number of theories that aim at accounting for attraction misalignment.     

Time courses in visual-information processing: Some theoretical considerations

Summary In the literature two different views with regard to the time course of activation of recognition units —hypothetical entities that represent identity information —are proposed. Both views are derived from a restricted set of phenomena in visual perception. The first view gets its intuitions from phenomena such as those summarized by Bloch's law; these phenomena show integration or summation of activation over time. This grow-and-grow view assumes that recognition units accumulate activation gradually over times The second view finds its inspiration in phenomena such as Mach-bands and simultaneous contrast; these phenomena show inhibition or steady-state suppression over time. This grow-and-shrink view assumes that the activation levels increase fast initially and then start to decrease.The perception literature strongly suggests that it may be light intensity that determines whether mainly integration (and phenomena such as Bloch's law) or inhibition (and phenomena such as Mach-bands) is obtained. So it is also likely that both information-processing views apply only to a limited range of intensity conditions; the grow-and-grow view to conditions of low-flight intensities, and the grow-and-shrink view to conditions of intermediate-and high-light intensities.It is argued that, to arrive at a complete view, a visual phenomenon that applies to the complete range of light intensities should be taken as a background for generating hypotheses about time courses in visual-information processing. The Broca-Sulzer effect is such a phenomenon. Starting from this phenomenon a simple, synthesizing, information-processing model is derived that is compatible with both the grow-and-grow view and the grow-andshrink view. It is shown that, besides the relevant temporal properties, this model also produces the appropriate spatial properties.