The Confluence of Adverse Early Experience and Puberty on the Cortisol Awakening Response

Associations between early deprivation/neglect in the form of institutional care with the cortisol awakening response (CAR) were examined as a function of pubertal status among 12- and 13-year-old post-institutionalized youth. CARs indexed hypothalamic-pituitary-adrenocortical reactivity. Post-institutionalized youth were compared to youth adopted internationally from foster care (adoption control) and to nonadopted youth reared in families comparable in parental education and income to the adoptive families. Post-institutionalized youth exhibited a blunted CAR if they were at earlier but not if they were at later stages of puberty. Similarly, for both groups of internationally adopted youth combined, earlier but not later stages of puberty were associated with more blunted CARs at higher but not lower levels of parent-reported pre-adoption physical and social neglect.     

THE EFFECTS OF REARRANGING WARD ROUTINES ON COMMUNICATION AND EATING BEHAVIORS OF PSYCHOGERIATRIC PATIENTS

Several aspects of ward routine were changed to study the effects of environmental manipulation on the behavior of 21 psychogeriatric patients. Furniture was rearranged to be more conducive to conversation (i.e., grouped around tables instead of along corridor walls), and mealtime routines were changed to allow patients more time to eat, more freedom in choosing the composition of the meal, and more pleasant surroundings. Patients were divided into experimental and control groups, and data were collected on the frequency of verbal and tactile communication and degree of skill in eating behavior. Following baseline, environmental changes were introduced across behaviors. Results show that the frequency of communication increased for the experimental group, as compared to both baseline and the control group. Eating behavior also improved significantly for the experimental group. The study shows that minor changes in the physical environment can promote therapeutic change in the behavior of patients diagnosed as senile dementia.     

Reinforcement sensitivity theory and major motivational and self-regulatory processes in children

The present research explores the role of sensitivity in the BIS and the BAS as antecedents to cognitive and affective motivational processes in middle-school children. Two studies were initiated to examine the relationship between sensitivity in the behavioral inhibition system (BIS) and behavioral approach system (BAS) and several important motivational factors. The first study looked at the assumption that the BIS and the BAS are systematically linked to motives and achievement goals. The second study investigated the links between BIS/BAS and individual differences in self-regulatory processes and affect during problem-solving. The findings indicate that the motive to avoid failure, the inability to take action after failure and to initiate intended goal-directed activities, as well as the tendency to focus on avoiding misunderstanding are all grounded in threat responsiveness. Conversely, the motive to approach success, self-efficacy and the tendency to focus on comparison with others in a problem-solving setting are grounded in incentive responsiveness.     

Serum Lipids in Suicide Attempters

As other studies have shown possible associations of low serum cholesterol concentrations as well as serotonin and corticosteroid deviances with suicide or depression, the present study was undertaken to investigate the serum lipid levels in subgroups of suicide attempters. Serum lipids were determined in 72 suicide attempters. Cerebrospinal fluid monoamine metabolites and plasma cortisol levels were measured, and dexamethasone suppression tests were performed. Hopelessness and suicidality were rated by the Hopelessness Scale (HS) and the Suicidal Intent Scales (SIS). The mean total serum cholesterol (TSC) level was 5.0 ± 1.2 mmol/L. We found no significant correlations between TSC and the monoamine metabolites. High-density lipoprotein cholesterol showed positive correlations with the dopamine metabolite homovanillic acid (r = 0.39, p = 0.04) and the serotonin metabolite 5-hydroxyindoleacetic acid (r = 0.34, p = 0.07). The SIS and HS scales did not correlate significantly with serum lipids. “Violent” attempters showed somewhat higher serum lipid levels than “nonviolent” attempters. We found no significant differences in serum lipid levels between the diagnostic subgroups. Hence, we could not find much support for the hypothesis of associations between low cholesterol levels and decreased serotonin activity in the brain. However, this field merits further investigation.     

Perceived angle of oscillatory motion

The general background of these experiments was the fact, known from e.g. trapezoidal window experiments, that rotary motion under certain conditions is perceived as oscillation. The aim was to identify the variables that determine the perceived angle of this oscillatory motion. Different shapes and different methods of generating the stimulation were used. No effect was obtained when varying the degree of trapezoidality of trapezoids, the location of the axis of rotation, the size of the stimulus pattern and the speed of the change. Both the occurrence and the perceived angle of oscillation was effected, however, by the width-height ratio of the stimulation, a decreasing ratio giving increasing occurrence of oscillation and decreasing perceived angle.