Brain activation on pre-reading tasks reveals at-risk status for dyslexia in 6-year-old children

In this fMRI-study, 6-year-old children considered at risk for dyslexia were compared with an age-/gender-matched control group for differences in brain activation when presented with visual stimuli differing in demands for literacy processing. Stimuli were nameable pictures, brand logos familiar to children, and written words - these were either regularly spelled using early-acquired rules ("alphabetic") or more complex ("orthographic"). Brain responses distinguished between the presentation conditions, as a function of group, within many cortical areas. Activation in the alphabetic and orthographic conditions in the left angular gyrus correlated with individual at-risk index scores, and activation in inferior occipito-temporal regions further indicated differential activation for the two groups related to orthographic processing, especially. Since similar patterns are reported in adult dyslexics when processing written words, it appears that sensitivity to the cortical differentiation of reading networks is established prior to formal literacy training.     

Prevalence and correlates of gambling among 16 to 19-year-old adolescents in Norway

There is evidence that young people are at high risk of developing gambling disorders. The prevalence and correlates of gambling among youth therefore merit closer study. During spring 2004, a sample of 1,351 boys and girls (aged 16–19 years) from 151 high-school classes (clusters) participated in an internet survey about gambling. The response rate was 69.8%. The instruments used in the survey were the Hospital Anxiety and Depression Scale, the Alcohol Use Disorders Identification Test and the Massachusetts Adolescent Gambling Screen, in addition to questions about demography. Controlling for the design effect, the estimated prevalence rate was 2.5% for pathological gambling and 1.9% for problem gambling. In all, 7.3% of the boys and 0.6% of the girls fulfilled the criteria for pathological or problem gambling. The results of item analysis of the DSM-IV subscale of MAGS provide support for differential item functioning between boys and girls. A multiple logistic regression analysis revealed that gender (male: OR = 9.09), depression (OR = 9.23), alcohol abuse (OR = 3.62), and dissociation (OR = 1.96) were related to problem and pathological gambling. These results support the view that gambling disorders are best understood as part of an addictive behavior spectrum ( Jacobs, 2000 ).     

The role of learning data in causal reasoning about observations and interventions

Recent studies have shown that people have the capacity to derive interventional predictions for previously unseen actions from observational knowledge, a finding that challenges associative theories of causal learning and reasoning (e.g., Meder, Hagmayer, & Waldmann, 2008). Although some researchers have claimed that such inferences are based mainly on qualitative reasoning about the structure of a causal system (e.g., Sloman, 2005), we propose that people use both the causal structure and its parameters for their inferences. We here employ an observational trial-by-trial learning paradigm to test this prediction. In Experiment 1, the causal strength of the links within a given causal model was varied, whereas in Experiment 2, base rate information was manipulated while keeping the structure of the model constant. The results show that learners’ causal judgments were strongly affected by the observed learning data despite being presented with identical hypotheses about causal structure. The findings show furthermore that participants correctly distinguished between observations and hypothetical interventions. However, they did not adequately differentiate between hypothetical and counterfactual interventions.     

The Incredible Years Teacher Classroom Management Programme in Kindergartens: Effects of a Universal Preventive Effort

The purpose of this study was to identify preventive effects of the Incredible Years (IY) teacher classroom management (TCM) programme, which is employed in Norwegian kindergartens for 3-year-old to 6-year-old children. IY TCM is a universal preventive intervention intended to reduce the frequency of inappropriate types of behaviour and support children’s social- and emotional competence in kindergartens and schools. IY TCM was implemented in 46 kindergartens and compared to 46 matched kindergartens that did not receive the intervention. A total of 1049 children took part in the trial, 511 from the IY TCM group and 538 from the comparison group. Children’s behaviours were measured using well-validated instruments at the beginning and end of a school-year cycle, approximately 9 months later. Findings showed promising reductions in aggression, internalising and attention problems, and increases in social competence in the IY TCM kindergartens. In a sub-sample comprising children who scored equal to or above the 90th percentile on aggressive behaviour before the intervention, promising developments were found in social competence among the children in IY TCM kindergartens. The IY TCM lead to promising preventive effects in young children’s aggressive behaviours, internalisation, attention problems, and social competence in kindergartens in Norway. However, even if the changes were statistically significant, effect sizes were small. For children with severe behaviour problems, few positive results were found.     

ADHD Symptoms in Post-Institutionalized Children Are Partially Mediated by Altered Frontal EEG Asymmetry

Individual differences in the propensity for left versus right frontal electroencephalogram (EEG) asymmetry may underlie differences in approach/withdrawal tendencies and mental health deficits. Growing evidence suggests that early life adversity may shape brain development and contribute to the emergence of mental health problems. The present study examined frontal EEG asymmetry (FEA) following the transition to family care in children adopted internationally from institutional care settings between 15 and 36 months of age (N = 82; 46 female, 36 male). Two comparison groups were included: an international adoption control consisting of children adopted from foster care with little to no institutional deprivation (N = 45; 17 female, 28 male) and a post-adoption condition control consisting of children reared in birth families of the same education and income as the adoptive families (N = 48; 23 female, 25 male). Consistent with evidence of greater approach and impulsivity-related behavior problems in post-institutionalized (PI) children, PI status was associated with greater left FEA than found in the other two groups. In addition, left FEA served as a mediator between institutionalization and age 5 ADHD symptoms for girls. Age at adoption and other preadoption factors were examined with results suggesting that earlier adoption into a supportive family resulted in a more typical pattern of brain functioning. Findings support the idea that the capacity of brain activity to evidence typical functioning following perturbation may differ in relation to the timing of intervention and suggest that the earlier the intervention of adoption, the better.     

Will I Fit in and Do Well? The Importance of Social Belongingness and Self-Efficacy for Explaining Gender Differences in Interest in STEM and HEED Majors

Throughout the world, the labor market is clearly gender segregated. More research is needed to explain women’s lower interest in STEM (Science, Technology, Engineering and Mathematics) majors and particularly to explain men’s lower interest in HEED (Health care, Elementary Education, and the Domestic spheres) majors. We tested self-efficacy (competence beliefs) and social belongingness expectations (fitting in socially) as mediators of gender differences in interest in STEM and HEED majors in a representative sample of 1327 Swedish high school students. Gender differences in interest in STEM majors strongly related to women’s lower self-efficacy for STEM careers and, to a lesser degree, to women’s lower social belongingness expectations with students in STEM majors. Social belongingness expectations also partly explained men’s lower interest in HEED majors, but self-efficacy was not an important mediator of gender differences in interest in HEED. These results imply that interventions designed to lessen gender segregation in the labor market need to focus more on the social belongingness of students in the gender minority. Further, to specifically increase women’s interest in STEM majors, we need to counteract gender stereotypical competence beliefs and assure women that they have what it takes to handle STEM careers.     

Infant manual exploration of composite substrates

Everyday environments, even small regions within reach, vary dramatically in terms of material composition. Adapting one's manual behavior to such transitions can be considered to be an important element of skilled action. To investigate the origins of this ability, we presented 8-month-olds (n=24) and 10-month-olds (n=24) hard or soft objects on a composite tabletop substrate that was half rigid and half flexible. Results indicated infants explored the objects selectively and geared their manual behaviors, with or without an object in hand, to the particular substrate they contacted. More broadly, the study suggests that infant manual exploration is flexible even in the face of abrupt transitions in material structure. Such flexibility may support early attempts at problem solving and tool use.     

Efficiently assessing negative cognition in depression: an item response theory analysis of the Dysfunctional Attitude Scale

Despite a central role for dysfunctional attitudes in cognitive theories of depression and the widespread use of the Dysfunctional Attitude Scale, form A (DAS-A; A. Weissman, 1979), the psychometric development of the DAS-A has been relatively limited. The authors used nonparametric item response theory methods to examine the DAS-A items and develop a briefer version of the scale. Using DAS-A data obtained from depressed participants enrolled in 2 large depression treatment studies (N=367), the authors developed a 9-item DAS form (DAS-SF1). In addition, because 2 versions of the DAS are needed for certain study designs, they also developed a 2nd short version (DAS-SF2). These short forms were highly correlated with the original 40-item DAS-A (rs ranged from .91 to .93), exhibited change similar to that of the DAS-A over the course of treatment, were moderately correlated with related self-report assessments, predicted concurrent depression severity, and predicted change in depression from before to after treatment. Taken together, the authors believe the DAS-SF1 and DAS-SF2 provide an efficient and accurate assessment of dysfunctional attitudes among depressed individuals.     

The genetic versus pharmacological invalidation of the cannabinoid CB(1) receptor results in differential effects on 'non-associative' memory and forebrain monoamine concentrations in mice

The endocannabinoid CB(1) receptor has been implicated in the inhibitory control of learning and memory. In the present experiment, we compared the behavioral response of CB(1) receptor knockout mice (CB(1)R(-/-)) with animals administered CB(1) receptor antagonist/inverse agonist SR141716A (rimonabant; 3 mg/kg IP, 30 min pre-trial) in terms of acquisition and retention of a habituation task and changes in cerebral monoamines. The results can be summarized as follows: (i) the acute and chronic invalidation of the CB(1) receptor resulted in an increase of behavioral habituation during the first exposure to an open field, indicative of enhanced acquisition of the task; (ii) CB(1)R(-/-) mice, but not rimonabant-treated animals, showed enhanced retention of the habituation task when re-tested 48 h and 1 week subsequent to the first exposure to the open field, respectively; (iii) the facilitation of retention of the habituation task in CB(1)R(-/-) mice was accompanied by a selective and site-specific increase in serotonin activity in hippocampus; and (iv) rimonabant-treated animals displayed 'antidepressant-like' neurochemical alterations of cerebral monoamines, that is, most parameters of monoaminergic activity were increased especially in dorsal striatum and hippocampus. Taken together, the present findings demonstrate that the genetic disruption of the CB(1) receptor gene can cause an improvement of behavioral habituation, which is considered to represent a form of 'non-associative' learning. Furthermore, our data support the assumption of a rimonabant-sensitive cannabinoid receptive site that is different from the 'classical' CB(1) receptor and which, under physiological conditions, might be involved in the inhibitory control of the acquisition but not retention of non-associative learning tasks.