Medical Genetics and Genetic Counseling in Chile

In the South American Republic of Chile genetic counseling is not currently recognized as an independent clinical discipline, and in general is provided by physicians with training in clinical genetics. At present only one genetic counselor and 28 clinical geneticists practice in this country of over 16 million inhabitants. Pediatric dysmorphology constitutes the primary area of practice in clinical genetics. Although the country has a universal health care system and an adequate level of health care, genetic conditions are not considered a health care priority and there is a lack of clinical and laboratory resources designated for clinical genetics services. Multiple educational, cultural and financial barriers exist to the growth and development of genetic counseling services in Chile. However, during the last 10 years increased awareness of the importance of identifying individuals at risk for inherited cancer syndromes led to growing interest in the practice of cancer genetics.     

Neither Here nor There,I Do Not Vote and I Do Not Care: The External Electoral Participation of Mexican Migrants in New Zealand

In 2006, an estimated 4.2 million Mexican emigrants were entitled to vote in presidential elections in Mexico, making this country the highest potential recipient of external votes around the world. Despite this fact, during the 2006 and 2012 presidential elections, less than 1 % of that estimated population actually casted their external votes raising questions about how previous patterns of political behavior can transcend borders and accompany migrants to their new countries. In this work, I argue that Mexican migrants’ interaction with an established democracy such as New Zealand is not a fundamental reason to encourage political participation through external voting. Through a qualitative lens, the paper attempts to analyze sentiments, attitudes, and behaviors of Mexican migrants toward the political arena and their effect in preventing or encouraging formal participation in Mexican elections. I conclude that cultural patterns of electoral behavior that originated in Mexico play a decisive role in the way Mexicans relate to their native country, regardless of the intensity of political integration to New Zealand democracy.     

Association Between Socio-Ecological Risk Factor Clustering and Mental,Emotional, and Behavioral Problems in Hispanic Adolescents

Compared to non-Hispanic whites, Hispanic adolescents in the U.S. report higher rates of several mental, emotional, and behavioral problems such as substance use, sexual risk behaviors, and internalizing and externalizing problems. There is evidence of common pathways in the development of mental, emotional, and behavioral problems with certain subgroups of Hispanic adolescents being at greater risk. In the present article, we report analysis of baseline data for 959 Hispanic adolescents who participated in one of two randomized controlled trials evaluating a family-based preventive intervention. Utilizing latent class analysis, we identified subgroups of Hispanic adolescents based on socio-ecological risk and protective factors (e.g., parent–adolescent communication, parental involvement in school). Three distinct socio-ecological risk subgroups (high, medium, and low risk) were identified and exhibited significant differences from each other across a majority of socio-ecological risk and protective factors. Adolescents in higher socio-ecological risk subgroups reported greater mental, emotional, and behavioral problems across all outcomes. Individual comparisons revealed significant differences between the low socio-ecological risk group and both the medium and high socio-ecological risk group in lifetime alcohol use, smoking, and sex, as well as internalizing and externalizing problems. Implications for intervention include focusing on specific risk subgroups and targeting shared risk and protective factors rather than specific mental, emotional, and behavioral outcomes.     

Expertise in complex decision making: the role of search in chess 70 years after de Groot

One of the most influential studies in all expertise research is de Groot's (1946) study of chess players, which suggested that pattern recognition, rather than search, was the key determinant of expertise. Many changes have occurred in the chess world since de Groot's study, leading some authors to argue that the cognitive mechanisms underlying expertise have also changed. We decided to replicate de Groot's study to empirically test these claims and to examine whether the trends in the data have changed over time. Six Grandmasters, five International Masters, six Experts, and five Class A players completed the think-aloud procedure for two chess positions. Findings indicate that Grandmasters and International Masters search more quickly than Experts and Class A players, and that both groups today search substantially faster than players in previous studies. The findings, however, support de Groot's overall conclusions and are consistent with predictions made by pattern recognition models.     

The development of gyrification in childhood and adolescence

Gyrification is the process by which the brain undergoes changes in surface morphology to create sulcal and gyral regions. The period of greatest development of brain gyrification is during the third trimester of pregnancy, a period of time in which the brain undergoes considerable growth. Little is known about changes in gyrification during childhood and adolescence, although considering the changes in gray matter volume and thickness during this time period, it is conceivable that alterations in the brain surface morphology could also occur during this period of development. The formation of gyri and sulci in the brain allows for compact wiring that promotes and enhances efficient neural processing. If cerebral function and form are linked through the organization of neural connectivity, then alterations in neural connectivity, i.e., synaptic pruning, may also alter the gyral and sulcal patterns of the brain. This paper reviews developmental theories of gyrification, computational techniques for measuring gyrification, and the potential interaction between gyrification and neuronal connectivity. We also present recent findings involving alterations in gyrification during childhood and adolescence.     

A robust approach for analyzing unbalanced factorial designs with fixed levels

The goal of this study was to investigate the performance of Hall’s transformation of the Brunner-Dette-Munk (BDM) and Welch-James (WJ) test statistics and Box-Cox’s data transformation in factorial designs when normality and variance homogeneity assumptions were violated separately and jointly. On the basis of unweighted marginal means, we performed a simulation study to explore the operating characteristics of the methods proposed for a variety of distributions with small sample sizes. Monte Carlo simulation results showed that when data were sampled from symmetric distributions, the error rates of the original BDM and WJ tests were scarcely affected by the lack of normality and homogeneity of variance. In contrast, when data were sampled from skewed distributions, the original BDM and WJ rates were not well controlled. Under such circumstances, the results clearly revealed that Hall’s transformation of the BDM and WJ tests provided generally better control of Type I error rates than did the same tests based on Box-Cox’s data transformation. Among all the methods considered in this study, we also found that Hall’s transformation of the BDM test yielded the best control of Type I errors, although it was often less powerful than either of the WJ tests when both approaches reasonably controlled the error rates.     

Virtual reality applications to agoraphobia: a protocol.

Recently, educators and instructional designers have focused on the development and implementation of virtual learning environments that effectively combine theoretical and applied knowledge to teach university students. One of the trusts of the Psychology Virtual Teaching Laboratory in collaboration with the IXTLI observatory is to develop dissemination programs to promote the insertion of virtual reality (VR) technologies applied to rehabilitation in their clinical practice. This paper describes the development of (1) agoraphobia VR learning objects to be use as a teaching support tools in class and (2) a multimedia teaching program that incorporate digital video and VR scenarios address to students in the field of mental health. Promotion among professors and students about the use of this technology will allow us to initiate research in our country as well as to validate contextualized applications for our culture, therefore contributing with new advances in this field.     

NATIVITY AND YEARS IN THE RECEIVING CULTURE AS MARKERS OF ACCULTURATION IN ETHNIC ENCLAVES

The current study was conducted to ascertain the validity of two commonly used markers of acculturation (nativity and years in the receiving culture) in an enclave context. Relationships between these markers and a bidimensional measure of acculturation were examined in a convenience sample of Hispanic immigrant adolescents and their caregivers in Miami. Nativity was examined using adolescent-reported data; approximately half of the youth were U.S.-born and half foreign-born, but all of the caregivers were foreign-born. Years in the receiving culture was examined using both adolescent and caregiver data. Results indicated that nativity was significantly associated with adoption of receiving-culture practices, with a small to moderate effect size. Years in the receiving culture was significantly associated with adoption of receiving-culture practices only for adolescent girls and for female caregivers who immigrated as youth. Neither nativity nor years in the receiving culture explained even moderate amounts of variance in retention or loss of culture-of-origin practices.     

Can Cognitive‐Behavioral Therapy Be Optimized With Parent Psychoeducation? A Randomized Effectiveness Trial of Adolescents With Major Depression in Puerto Rico

This is a longitudinal randomized control trial on the impact of adding a parent psychoeducation intervention (TEPSI) as part of cognitive‐behavioral therapy (CBT) for adolescents with Major Depressive Disorder (MDD) in a Puerto Rican sample. We tested the efficacy of adding 8 group sessions of TEPSI to 12 sessions of individual CBT on reducing depressive symptoms, MDD diagnosis, and improving family functioning. Participants (n = 121) were randomized to individual CBT with or without TEPSI. No main group effects were found for most patient domains including depression symptoms, as well as presence of adolescent's MDD diagnosis at posttreatment. Results did show a main effect of CBT over time for depression symptoms, suicide ideation, family criticism, and the presence of MDD diagnosis decreasing from pre‐ to postintervention. A year post treatment, almost 70% of adolescents in both conditions (CBT and CBT + TEPSI) remained in remission. A main effect was obtained for treatment in the adolescent's perception of familism and family emotional involvement. The primary hypothesis that family psychoeducation would optimize CBT for depression in adolescents was not supported. Both conditions yielded similar clinical end points. The culturally adapted CBT was found effective with Latino/a adolescents showing clinically significant improvements from pretreatment to posttreatment and remained stable at a 1‐year follow‐up. Regarding family outcomes, adolescents in CBT + TEPSI remained stable from pretreatment to posttreatment on family emotional involvement, while adolescents in CBT‐alone showed an increase. The implication of these findings is discussed.     

Husserl on Analyticity and Beyond

Quine’s criticism of the notion of analyticity applies, at best, to Carnap’s notion, not to those of Frege or Husserl. The failure of logicism is also the failure of Frege’s definition of analyticity, but it does not even touch Husserl’s views, which are based on logical form. However, some relatively concrete number-theoretic statements do not admit such a formalization salva veritate. A new definition of analyticity based not on syntactical but on semantical logical form is proposed and argued for.

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