Automatic detection of transient potentials in the EEG

A classifier based on the linear regression model was developed to automatically detect sharp transients in EEG, matching the definition of spikes and sharp waves accepted by IFSECN. Practical applications proved the accuracy of the method which succeeded in detecting 84% of sharp transients previously found by an experienced electronencephalographer. Computerized search for sharp transients in EEG records will be particularly useful in long term EEG records obtained from epileptic patients.     

Diagnostic value of myelography as an expanded clinical study method

The paper investigates 54 myelograms and their influence on diagnostic thinking efficacy, on patient management efficacy, and on ultimate outcome efficacy, using statistical methods. Conventional myelography contributes to diagnostic thinking efficacy having a LLR- value of approximately 0.9. With an accuracy value of 0.95 it can be regarded as a reliable method of diagnosis. It alters diagnostic thinking efficacy in no less than 83% (94%) of the cases and patients management efficacy in 89%. Thus, by definition, myelography may be said to affect the state of health of the myelographed patients in 94.4%.     

Psychopathology of progressive paralysis. Remarks on some personal cases

Four of our own cases that presented a clinical picture of dementia are discussed. A study of the relative literature has failed to reveal any "swing" in the pattern of the clinical condition: Just as it did ninety years age, paralytic dementia accounts today for well over 60% of all cases, those clinical pictures erroneously regarded as "typical" "classic", accounting for a mere 10%-15% of cases. The need for routine lues serology is pointed out.     

On structural equation modeling with data that are not missing completely at random

A general latent variable model is given which includes the specification of a missing data mechanism. This framework allows for an elucidating discussion of existing general multivariate theory bearing on maximum likelihood estimation with missing data. Here, missing completely at random is not a prerequisite for unbiased estimation in large samples, as when using the traditional listwise or pairwise present data approaches. The theory is connected with old and new results in the area of selection and factorial invariance. It is pointed out that in many applications, maximum likelihood estimation with missing data may be carried out by existing structural equation modeling software, such as LISREL and LISCOMP. Several sets of artifical data are generated within the general model framework. The proposed estimator is compared to the two traditional ones and found superior.The research of the first author was supported by grant No. SES-8312583 from the National Science Foundation and by a Spencer Foundation grant. We wish to thank Chuen-Rong Chan for drawing the path diagram.     

Flicker contrast sensitivity in normal and specifically disabled readers

Temporal contrast sensitivity for counterphase flicker was determined for specifically disabled and normal readers to investigate whether the two groups differ in the functioning of their transient systems. In experiment 1, temporal contrast sensitivity was measured over a range of temporal frequencies with a spatial frequency of 2 cycles deg-1. Disabled readers were less sensitive than the control subjects at all temporal frequencies. In experiment 2, temporal contrast sensitivity was measured at a temporal frequency of 20 Hz over a range of spatial frequencies. Disabled readers were less sensitive than the controls at all spatial frequencies, with the differences between the groups increasing as spatial frequency increased. Both these findings are interpreted as supporting the hypothesis of a transient-system deficit in the visual systems of disabled readers.     

Brain potentials as indices of orthographic and phonological interaction during word matching

The interaction between orthographic and phonological codes in a same-different judgment task was studied by requiring subjects to decide if two visually presented words either looked alike or rhymed. Word pairs were selected from four different lists. Words rhymed and looked alike, rhymed but did not look alike, looked alike but did not rhyme, or neither looked alike nor rhymed. Reaction time and percent error increased whenever there was a conflict between the orthography and phonology of the words. The N200 component of the event-related brain potential (ERP) indicated that subjects were capable of detecting phonological differences between words within 260 ms from the presentation of a word pair. The amplitude of the N200s also varied with the degree of mismatch between words. N200s were largest when both the orthography and phonology mismatched, of intermediate amplitude when either orthography or phonology mismatched, and smallest when both orthography and phonology matched. P300 latency was consistent with reaction time, increasing whenever there was a conflict between the two codes. Taken together, behavioral measures and the ERP data suggest that the extraction of the orthographic and phonological aspects of words occurs early in the information processing sequence.