Central galanin administration blocks consolidation of spatial learning

Galanin is a neuropeptide that inhibits the evoked release of several neurotransmitters, inhibits the activation of intracellular second messengers, and produces deficits in a variety of rodent learning and memory tasks. To evaluate the actions of galanin on encoding, consolidation, and storage/retrieval, galanin was acutely administered to Sprague-Dawley rats at time points before and after training trials in the Morris water maze. Intraventricular administration of galanin up to 3h after subjects had completed daily training trials in the Morris water task impaired performance on the probe trial, indicating that galanin-blocked consolidation. Pretreatment with an adenylate cyclase activator, forskolin, prevented the deficits in distal cue learning produced by galanin. Di-deoxyforskolin, an inactive analog of forskolin, had no effect. These results provide the first evidence that galanin interferes with long-term memory consolidation processes. A potential mechanism by which galanin produces this impairment may involve the inhibition of adenylate cyclase activity, leading to inhibition of downstream molecular events that are necessary for consolidation of long-term memory.     

Degrees of maximality of Klukasiewicz-like sentential calculi

The paper is concerned with the problem of characterization of strengthenings of the so-called Lukasiewicz-like sentential calculi. The calculi under consideration are determined byn-valued Lukasiewicz matrices (n>2,n finite) with superdesignated logical values. In general. Lukasiewicz-like sentential calculi are not implicative in the sense of [7]. Despite of this fact, in our considerations we use matrices analogous toS-algebras of Rasiowa. The main result of the paper says that the degree of maximality of anyn-valued Lukasiewicz-like sentential calculus is finite and equal to the degree of maximality of the correspondingn-valued Lukasiewicz calculus. Allatum est die 15 Octobris 1976     

Frontal EEG alpha band asymmetry as a predictor of reasoning deficiency in depressed people

Cognitive deficits in depression are mostly apparent in executive functions, especially when integration of information and reasoning is required. In parallel, there are also numerous studies pointing to the frontal alpha band asymmetry as a psychophysiological marker of depression. In this study, we explored the role of frontal alpha asymmetry as a potential factor explaining the cognitive problems accompanying depression. Twenty-six depressed and 26 control participants completed a reasoning task and underwent 5 minutes of electroencephalography recording. In line with the previous studies, depressed people showed difficulties with reasoning but we did not observe the relationship between frontal asymmetry in the alpha band and depression. However, we found that in the depressed group the frontal alpha asymmetry index was characterised by larger variance than in the control group, and it was also a strong predictor of cognitive functioning exclusively in the depressed group. Our results point to the disruption of a psychophysiological balance, reflected in changed frontal alpha asymmetry (into more left-sided frontal asymmetry in the alpha band, reflecting more right-sided cortical activity) as a possible brain correlate of cognitive disturbances present in depressive disorders.     

Positive effects of subclinical depression in prospective memory and ongoing tasks in young and old adults

Results reported in the literature show that depression can have either negative or neutral effects on prospective memory (PM). The goal of the present study was to broaden the analysis of depression-related effects on PM, with regard to the possibility that subclinical depression may have positive influence on PM. A total of 120 participants from four groups (young/old, subclinically depressed/non-depressed) completed event- and time-based PM tasks embedded in the linear orders task or stories task, respectively. In the event-based PM task no effects of depression were found, whereas depressed participants were more accurate in the time-based PM task, where higher monitoring during the last minute of the task was observed. It was also found that depressed participants built a mental model in the linear orders task more accurately than controls. Results of the present study are discussed with reference to the analytical rumination hypothesis.     

Intuitive (in)coherence judgments are guided by processing fluency, mood and affect

Recently proposed accounts of intuitive judgments of semantic coherence assume that processing fluency results in a positive affective response leading to successful assessment of semantic coherence. The present paper investigates whether processing fluency may indicate semantic incoherence as well. In two studies, we employ a new paradigm in which participants have to detect an incoherent item among semantically coherent words. In Study 1, we show participants accurately indicating an incoherent item despite not being able to provide an accurate solution to coherent words. Further, this effect is modified by affective valence of solution words that are not retrieved from memory. Study 2 replicates those results and extend them by showing that mood moderates incoherence judgments independently of affective valence of solutions. The results support processing fluency account of intuitive semantic coherence judgments and show that it is not fluency per se but fluency variations that drive judgments.     

Family Therapy in Poland: Development and Current Perspectives

The authors of the present article describe the historical context of family therapy in Poland and current issues in the field. They highlight the fact that Polish therapists first began to develop the field after coming into contact with family therapy leaders from the United States and Western Europe. With the political breakthrough of 1989, there were new opportunities for multilateral cooperation, attendance at international conferences, and the exchange of experiences. Currently, the work of Polish family therapists, the place of family therapy among other forms of psychotherapy, and the related problems and challenges do not differ from other European nations.     

Action rules: why the visual control of reaching and grasping is not always influenced by perceptual illusions

It is generally accepted that vision first evolved for the distal control of movement and that perception or 'representational' vision emerged much later. Vision-for-action operates in real time and uses egocentric frames of reference and the real metrics of the world. Vision-for-perception can operate over longer time scales and is much more scene-based in its computations. These differences in the timing and metrics of the two systems have been examined in experiments that have looked at the way in which each system deals with visual illusions. Although controversial, the consensus is that actions such as grasping and reaching are often unaffected by high-level pictorial illusions, which by definition affect percetion. However, recent experiments have shown that, for actions to escape the effects of such illusions, they must be highly practiced actions, preferably with the right hand, and must be directed in real time at visible targets. This latter finding suggests that some of the critical components of the encapsulated (bottom-up) systems that mediate the visual control of skilled reaching and grasping movements are lateralised to the left hemisphere.     

Logic, Formal Methodology and Semantics in Works of Ryszard W��jcicki

For decades Ryszard Wójcicki has been a highly influential scholar in the community of logicians and philosophers. Our aim is to outline and comment on some essential issues on logic, methodology of science and semantics as seen from the perspective of distinguished contributions of Wójcicki to these areas of philosophical investigations.