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101.
Dissociable patterns of brain activity during comprehension of rapid and syntactically complex speech: evidence from fMRI 总被引:7,自引:0,他引:7
Sentence comprehension is a complex task that involves both language-specific processing components and general cognitive resources. Comprehension can be made more difficult by increasing the syntactic complexity or the presentation rate of a sentence, but it is unclear whether the same neural mechanism underlies both of these effects. In the current study, we used event-related functional magnetic resonance imaging (fMRI) to monitor neural activity while participants heard sentences containing a subject-relative or object-relative center-embedded clause presented at three different speech rates. Syntactically complex object-relative sentences activated left inferior frontal cortex across presentation rates, whereas sentences presented at a rapid rate recruited frontal brain regions such as anterior cingulate and premotor cortex, regardless of syntactic complexity. These results suggest that dissociable components of a large-scale neural network support the processing of syntactic complexity and speech presented at a rapid rate during auditory sentence processing. 相似文献
102.
Patients with Parkinson's disease (PD) have sentence comprehension difficulty, but it is unclear whether this is due to a deficit in grammatical processing or to an executive resource limitation. To assess grammatical processing in PD while minimizing task-related demands, PD patients and healthy control subjects performed a word detection procedure that assesses sensitivity to grammatical agreements in sentences in an "on-line" fashion. With this technique, we found that control subjects and PD patients are equally sensitive to grammatical agreement violations in sentences. A traditional, resource-demanding measure of sentence comprehension was also administered to the same PD patients. In comparison to healthy controls, PD patients were significantly impaired in their relative comprehension of sentences containing object-gap subordinate clauses compared to subject-gap subordinate clauses. Performance on several executive resource measures was also impaired in PD, and this correlated with their comprehension performance. Sensitivity to grammatical agreements with the word detection procedure, in the context of sentence comprehension difficulty on a traditional measure, suggests that PD patients' executive resource limitations contribute to their sentence comprehension difficulty. 相似文献
103.
Casasanto DJ Killgore WD Maldjian JA Glosser G Alsop DC Cooke AM Grossman M Detre JA 《Brain and language》2002,80(3):287-295
Recent neuroimaging studies suggest that episodic memory encoding involves a network of neocortical structures which may act interdependently with medial temporal lobe (mTL) structures to promote the formation of durable memories, and that activation in certain structures is modulated according to task performance. Functional magnetic resonance imaging (fMRI) was used to determine the neural structures recruited during a verbal episodic encoding task and to examine the relationship between activation during encoding and subsequent recognition memory performance across subjects. Our results show performance-correlated activation during encoding both in neocortical and medial temporal structures. Neocortical activations associated with later successful and unsuccessful recognition memory were found to differ not only in magnitude, but also in hemispheric laterality. These performance-related hemispheric effects, which have not been previously reported, may correspond to between-subject differences in encoding strategy. 相似文献
104.
Many patients with frontotemporal dementia (FTD) have impaired sentence comprehension. However, the pattern of comprehension difficulty appears to vary depending on the clinical subgroup. The purpose of this study was to elucidate the neural basis for these deficits in FTD. We studied patients with two different presentations: Three patients with Progressive Non-Fluent Ahasia (PNFA), and five non-aphasic patients with a dysexecutive and social impairment (EXEC). The FTD patient subgroups were compared to a cohort of 11 healthy seniors with intact sentence comprehension. We monitored regional cerebral activity with blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) while subjects read sentences featuring both a grammatically complex object-relative center-embedded clause and a long linkage between the head noun phrase (NP) and the gap where the NP is interpreted in the center-embedded clause. Subjects decided whether the agent of the action is a male or a female. Healthy seniors activated both ventral portions of inferior frontal cortex (vIFC) and dorsal portions of IFC (dIFC) in the left hemisphere, often associated with grammatical and working memory components of these sentences, respectively. PNFA patients differed from healthy controls since they have reduced activation of left vIFC, while EXEC patients have less recruitment of left dIFC. We conclude that FTD subgroups have distinct patterns of sentence comprehension difficulty in part because of selective interruptions of a large-scale neural network for sentence processing. 相似文献
105.
Motivation and Emotion - In this short commentary we argue that feelings of contempt play a major role in schadenfreude (joy in the misfortunes of others) and “reverse... 相似文献
106.
Number sense and quantifier interpretation 总被引:1,自引:1,他引:0
We consider connections between number sense—the ability to judge number—and the interpretation of natural language quantifiers.
In particular, we present empirical evidence concerning the neuroanatomical underpinnings of number sense and quantifier interpretation.
We show, further, that impairment of number sense in patients can result in the impairment of the ability to interpret sentences
containing quantifiers. This result demonstrates that number sense supports some aspects of the language faculty.
相似文献
Robin ClarkEmail: |
107.
Hearing loss is a confounding variable that is rarely addressed in behavioral research despite its prevalence across the life span. Currently, the most common method of experimental control over hearing acuity is through self report of perceived impairment. We argue that this technique may lack sensitivity and that researchers should more commonly utilize standardized hearing screening procedures. Distinctive patterns of hearing loss are reviewed with attention to populations that commonly participate in behavioral research. We explain standard techniques for conducting pure tone hearing screening using a conventional portable audiometer and outline a procedure for how researchers can modify a conventional laptop computer for audiometric screening when a standard audiometer is unavailable. We offer a sample hearing screening program that researchers may use toward the development of their own protocol. This program is freely available for download at www .psychonomic.org/archive. 相似文献
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