Hippocampal differentiation without recognition: an fMRI analysis of the contextual cueing task

A central role of the hippocampus is to consolidate conscious forms of learning and memory, while performance on implicit tasks appears to depend upon other structures. Recently, considerable debate has emerged about whether hippocampal-dependent tasks necessarily entail task awareness. In the contextual cueing task, repetition facilitation is implicit, but impaired in patients with amnesia. Whether the hippocampus alone or other MTL structures are required is unclear. Event-related functional magnetic resonance imaging revealed hippocampal activity that differentiates novel from repeated arrays. This pattern of results was observed without recognition of the repeating arrays. This finding provides support for the claim that the hippocampus is involved in processes outside the domain of conscious learning and memory.     

Crawling is associated with more flexible memory retrieval by 9-month-old infants

In the present experiment, we used a deferred imitation paradigm to explore the effect of crawling on memory retrieval by 9-month-old human infants. Infants observed an experimenter demonstrate a single target action with a novel object and their ability to reproduce that action was assessed after a 24-hr delay. Some infants were tested with the demonstration stimulus in the demonstration context and some infants were tested with a different stimulus in a different context. Half of the infants in each test condition were crawling at the time of participation and half were not. Both crawling and non-crawling infants exhibited retention when tested with the demonstration stimulus in the demonstration context, but only infants who were crawling by 9 months of age exhibited retention when tested with a different stimulus in a different context. These findings demonstrate that the onset of independent locomotion is associated with more flexible memory retrieval during the first year of life.     

Automatic Emotion Regulation

How do people effectively regulate their emotional reactions? Why are some people better at this than others? Most prior research has addressed these questions by focusing on deliberate forms of emotion regulation. We argue that this focus has left out an important aspect of emotion regulation, namely, automatic emotion regulation (AER). Our review of the behavioral literature suggests that AER is pervasive in everyday life, and has far‐reaching consequences for individuals’ emotions. However, the behavioral literature has yet to address the mechanisms underlying the observed effects. Because it is difficult to directly measure the processes involved in AER, evidence from neuroscientific studies is particularly helpful in addressing these questions. Our review of the neuroscientific literature suggests distinct neural bases for different types of AER, which provides important clues about the cognitive and behavioral processes that might be involved in AER.     

Sentence processing in Lewy body spectrum disorder: the role of working memory

Prior work has related sentence processing to executive deficits in non-demented patients with Parkinson's disease (PD). We extended this investigation to patients with dementia with Lewy bodies (DLB) and PD dementia (PDD) by examining grammatical and working memory components of sentence processing in the full range of patients with Lewy body spectrum disorder (LBSD). Thirty-three patients with LBSD were given a two-alternative, forced-choice sentence-picture matching task. Sentence type, working memory, and grammatical structure were systematically manipulated in the sentences. We found that patients with PDD and DLB were significantly impaired relative to non-demented PD patients and healthy controls. The deficit in PDD/DLB was most pronounced for sentences lengthened by the strategic placement of an additional prepositional phrase and for sentences with an additional proposition due to a center-embedded clause. However, there was no effect for subject-relative versus object-relative grammatical structure. An MRI voxel-based morphometry analysis in a subset of patients showed significant gray matter thinning in the frontal lobe bilaterally, and this extended to temporal, parietal and occipital regions. A regression analysis related sentence processing difficulty in LBSD to frontal neocortex, including inferior prefrontal, premotor, and dorsolateral prefrontal regions, as well as right superior temporal cortex. These findings are consistent with the hypothesis that patients with PDD and DLB have difficulty processing sentences with increased working memory demands and that this deficit is related in part to their frontal disease.     

Psychometric evaluation of the Fear of Positive Evaluation Scale in patients with social anxiety disorder

The Fear of Positive Evaluation Scale (FPES; J. W. Weeks, R. G. Heimberg, & T. L. Rodebaugh, 2008) was designed to assess fear of positive evaluation, a proposed cognitive component of social anxiety. Although previous findings on the psychometric properties of the FPES have been highly encouraging, only 1 previous study has examined the psychometric profile of the FPES in a sample of patients with social anxiety disorder (T. A. Fergus et al., 2009). The primary purpose of the present study was to conduct a large multisite examination of the psychometric profile of the FPES among patients with a principal diagnosis of social anxiety disorder (n = 226; generalized subtype = 97.8%). Responses of nonanxious control participants (n = 42) were also examined. The factorial validity, internal consistency, test-retest reliability, construct validity, and treatment sensitivity of the FPES were strongly supported by our findings. Furthermore, an FPES cutoff score was identified for distinguishing levels of fear of positive evaluation characteristic of patients with social anxiety disorder from those characteristic of the control group. Results provide additional support for the psychometric properties of the FPES in clinical samples.     

When trying is not enough: Emotion regulation and the effort-success gap in bipolar disorder

Bipolar disorder (BD) is presumed to involve difficulties in emotion regulation. Little is known, however, about the specific emotion regulation profile associated with this disorder. The present study examined the use of specific emotion regulation strategies among individuals with BD (n = 37) and healthy controls (n = 38). Participants' spontaneous use of reappraisal and suppression, as well as their associated effort and success at regulating their emotions, was measured in the context of three emotionally evocative films (neutral, happy, sad). Results indicated that the BD participants made greater use of spontaneous suppression and reappraisal across all films compared to the control group. BD participants also reported greater effort, but less success, when spontaneously regulating emotions. These findings suggest that bipolar disorder is associated with less success when regulating emotions despite a widespread engagement of regulatory efforts. Discussion focuses on the disjunction between troubled emotion functioning in bipolar disorder and sustained efforts to modify intense emotions. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Emotion regulation in Asperger's syndrome and high-functioning autism

It is generally thought that individuals with Asperger's syndrome and high-functioning autism (AS/HFA) have deficits in theory of mind. These deficits have been previously linked to problems with social cognition. However, we reasoned that AS/HFA individuals' Theory of Mind deficits also might lead to problems with emotion regulation. To assess emotional functioning in AS/HFA, 27 AS/HFA adults (16 women) and 27 age-, gender-, and education-matched typically developing (TD) participants completed a battery of measures of emotion experience, labeling, and regulation. With respect to emotion experience, individuals with AS/HFA reported higher levels of negative emotions, but similar levels of positive emotions, compared with TD individuals. With respect to emotion labeling, individuals with AS/HFA had greater difficulties identifying and describing their emotions, with approximately two-thirds exceeding the cutoff for alexithymia. With respect to emotion regulation, individuals with AS/HFA used reappraisal less frequently than TD individuals and reported lower levels of reappraisal self-efficacy. Although AS/HFA individuals used suppression more frequently than TD individuals, no difference in suppression self-efficacy was found. It is important to note that these differences in emotion regulation were evident even when controlling for emotion experience and labeling. Implications of these deficits are discussed, and future research directions are proposed.     

Selection,Optimization, and Compensation in the Domain of Emotion Regulation: Applications to Adolescence,Older Age,and Major Depressive Disorder

Emotions often are well calibrated to the challenges and opportunities we face. When they are not, we may try to regulate our emotions. Interestingly, there seems to be considerable variation both in the strategies people use to regulate emotions and in the success of these emotion regulation efforts. The Selection, Optimization, and Compensation with Emotion Regulation framework suggests that variation in the resources required for particular emotion regulation strategies may be a crucial determinant of emotion regulation use and success within individuals across situations, between individuals, and between groups of individuals. In this review, we consider the ways in which two resources for emotion regulation (working memory and social support) might differ among three groups, namely adolescents, older adults, and adults with major depressive disorder. We link these between‐group differences in resources to differences in emotion regulation and make suggestions for future research.