Individual differences in dopamine D<Subscript>2</Subscript> receptor availability correlate with reward valuation

Reward valuation, which underlies all value-based decision-making, has been associated with dopamine function in many studies of nonhuman animals, but there is relatively less direct evidence for an association in humans. Here, we measured dopamine D₂ receptor (DRD2) availability in vivo in humans to examine relations between individual differences in dopamine receptor availability and neural activity associated with a measure of reward valuation, expected value (i.e., the product of reward magnitude and the probability of obtaining the reward). Fourteen healthy adult subjects underwent PET with [¹⁸F]fallypride, a radiotracer with strong affinity for DRD2, and fMRI (on a separate day) while performing a reward valuation task. [¹⁸F]fallypride binding potential, reflecting DRD2 availability, in the midbrain correlated positively with neural activity associated with expected value, specifically in the left ventral striatum/caudate. The present results provide in vivo evidence from humans showing midbrain dopamine characteristics are associated with reward valuation.     

A tale of two audiences: Narcissism,failure reactivity,and perceived criticism from the self and others as internalized audiences

We proposed a conceptual model which postulates that anticipating greater destructive (vs. constructive) criticism from the self and others partially explains the differentiation of narcissists’ failure reactivity as a function of narcissism subtype. Participants simulated failure, rated the likelihood of experiencing destructive and constructive criticism from social audiences (self and others [important other, unimportant other, social world]), and indicated failure reactivity (indexed as change in negative affect) following failure. Results generally supported our model. Vulnerable (grandiose) narcissism related to enhanced (reduced) failure reactivity and greater (less) anticipated destructive vs. constructive criticism from audiences, particularly the self. Controlling for perceived criticism from audiences attenuated relations between each narcissism subtype and failure reactivity, supporting the theoretical merit of our model.     

Neighborhood Concentrated Disadvantage and Dating Violence among Urban Adolescents: The Mediating Role of Neighborhood Social Processes

The link between relationship violence and aspects of neighborhood concentrated disadvantage (e.g., percent of unemployed adults, percent of families below poverty level), has been established. However, the literature examining neighborhood social processes, including informal social control and social cohesion, in relation to adolescent dating violence has shown mixed results with a limited theoretical foundation and methodology. Using a social disorganization theoretical framework, this study examined the mediating role of these neighborhood social processes in the relation between concentrated disadvantage and adolescent dating violence within an urban context. Participants included 605 adult residents in 30 census tracts and 203 adolescents from neighborhoods on the West and South sides of Chicago. Neighborhood‐level concentrated disadvantage was measured via Census data, adult residents reported on neighborhood social processes, and youth reported on dating violence. Informal social control was negatively associated with dating violence, and social cohesion was positively associated with dating violence. A multilevel mediation model showed that concentrated disadvantage was related to higher levels of dating violence via lower levels of informal social control. These results extend social disorganization theory to dating violence within an urban context, while also highlighting the important role of neighborhood processes on relationship violence. Implications for research and intervention programming are discussed.     

Intraindividual Dynamic Network Analysis – Implications for Clinical Assessment

A network analysis approach to psychopathology regards symptoms as mutually interacting components of a multifaceted system (Borsboom & Cramer, 2013). Although several studies using this approach have examined comorbidity between disorders using cross-sectional samples, a direct application of the network analysis approach to intraindividual dynamic relations between symptoms in a complex, comorbid case has not been reported. The current article describes an intraindividual dynamic network analysis (IDNA) approach to understanding the psychopathology of an individual using dynamic (over time) lead-lag interrelations between symptoms. Multivariate time series data were utilized to create and examine an intraindividual, lag-1 network of the partial, day-to-day relations of symptoms in an individual with comorbid mood and anxiety disorders. Characteristics of the network, including centrality indices, stability, dynamic processes between symptoms, and their implications for clinical assessment are described. Additional clinical implications and future directions for IDNA, including the potential incremental validity of this assessment approach for empirically-based idiographic assessment and personalized treatment planning, are discussed. This person-specific IDNA approach may be especially useful in complex and comorbid cases.     

Methodological functionalism and the description of natural systems

The primary way that explanations are constructed in cognitive psychology is by methodological functionalism: in short, functionally defined components are proposed in order to explain how inputs (i.e., stimuli from the environment) are turned into behavior. But despite its close association with cognitive psychology, methodological functionalism is a technique that can be used to describe any natural system. I look at how methodological functionalism has fared when used by other special sciences and what lessons can be learned from these cases. Three explanations of chemical and biological systems that were developed using methodological functionalism are examined: Willis’s (1684) explanation of fermentation, Farr’s (mid-1800s) explanation of cholera, and Mendel’s (mid-1800s) explanation of inheritance. The discovery of HIV in the early 1980s, an investigation that rejected methodological functionalism early on, is also discussed. The assessment of methodological functionalism is not positive. This technique has limitations. The implications for cognitive psychology are considered, and one conclusion is that cognitive psychology will eventually cease relying on methodological functionalism.     

Client Report of Delivery of Common Elements in Usual Care and the Association to Satisfaction

Recently, scholars have advocated for the use of a new flexible approach to evidence-based practice through the use of “common elements”, which are treatment procedures that are utilized in a variety of evidence-based mental health interventions. The objective of this study was to describe the extent to which clinicians are using common elements of evidence-based treatment (EBT) in routine mental health care for children and if they are utilizing more of the elements associated with their client’s diagnosis. A second objective was to determine whether use of these elements was associated with client satisfaction. The Youth Services Survey was administered to a diverse sample of youth and their caregivers (total sample = 1075) to measure satisfaction with services and use of both talk-based and skill-based common elements. More than 74 % of caregivers indicated that their child’s clinician utilized the talk-based common elements frequently or almost always. Additionally, at least 69 % of youth agreed with this finding. Youth and caregivers reported that the common elements related to skill building were utilized less frequently. A Generalized Estimating Equation approach was used to examine the relationship between use of common elements and client diagnosis and satisfaction. The results for diagnosis were mixed and varied by parent and youth report. Finally, the more clinicians discussed and practiced common elements of EBT with their clients, both youth and caregivers were more likely to be satisfied. Due to clients’ reporting that on average clinicians utilized skill building common elements less often, targeted clinician training may be important, since practicing skill-building therapeutic elements is key to adopting new methods of managing behavior and emotions. Further, if families are more satisfied with a common elements approach, then clinicians may be more likely to utilize it.     

Impaired Health-Related Quality of Life in Children and Families Affected by Methylmalonic Acidemia

An understanding of health related quality of life (HRQoL) in children and families affected by methylmalonic acidemia (MMA) is important in planning counseling and therapeutic intervention. Liver transplantation (LT) is used as a treatment for MMA; however, its risks and benefits continue to be investigated. The purpose of this study was twofold: (1) to measure HRQoL in children and families affected by MMA using the Pediatric Quality of Life Inventory (PedsQL?) parent version, and (2) to assess the impact of LT on HRQoL by comparing LT and non-LT patient scores and free responses. Parents/caregivers reported lower scores on the majority of the PedsQL? scales as compared to samples of healthy children, children with solid organ transplants for indications other than MMA, and families affected by chronic conditions. Scores for children with MMA were lowest in school and social functioning and scores for families were lowest in worry and activity impairment. There were no significant differences in LT and non-LT patient scores on the PedsQL? scales. Our results document the negative impact of MMA on HRQoL.     

Cognitive and affective components of empathy and their relationship with personality dimensions in a Chinese sample

Empathy is an essential component of social interactions and may be related to personality characteristics. However, this issue has not been extensively examined in a Chinese sample. Students at six universities in China (N = 257) completed the Interpersonal Reactivity Index (IRI), the Eysenck Personality Questionnaire‐Revised (EPQ‐R), and the Depression, Anxiety and Stress Scale (DASS‐21). Using multiple regression analyses, and after accounting for demographic variables (sex and age), it was found that the affective empathy component Personal Distress positively predicted EPQ‐R Neuroticism scores (β = .49), negatively predicted Extraversion (β = –.21) and Lie scale scores (β = –.22), and positively predicted DASS‐21 Depression (β = .26), Anxiety (β = .34) and Stress scores (β = .39). Empathic Concern positively predicted Lie Scale scores (β = .21), and negatively predicted Psychoticism scores (β = –.24). Individuals with high scores in Empathic Concern were also found to score more highly on Fantasy, Personal Distress, Neuroticism, Stress and Anxiety. Thus, more empathic individuals are likely to experience elevations in negative affectivity when they perceive the emotional suffering of others.