Using a virtual reality system to study balance and walking in a virtual outdoor environment: a pilot study.

Falls and fall-related injuries are a major problem for elderly persons. Most falls occur during walking and turning, and the risk of falling increases when attention is diverted to something besides walking. It is often difficult to standardize methods for testing balance and fall tendency in a clinically relevant setting. We describe the development of a system using a virtual environment (VE) to assess how attention demanding and unexpected events influence a person's capacity to control balance and movement. The hardware in the system consists of a head-mounted display (HMD), a magnetic tracker system, and two SGI computers. The software consists of the image generation of the VE and the management and visualization of motion tracking data. In a preliminary pilot study eight subjects (age 23-80) participated. Each subject walked on a normal floor and was visually presented a familiar outdoor environment in the HMD. They were exposed to different unexpected events, such as a virtual snowfall and tilting of the VE. Disturbances of balance and walking patterns such as changes in speed, stride length and balance reactions like slipping were observed. Two subjects experienced symptoms of cyber sickness with a SSQ score above 25 points. Walking with sensors only did not affect walking time, but in VE the subjects generally walked more slowly. Virtual tilting of the environment had an impact on balance performance during walking. This effect was not observed while the test subjects were walking in a virtual snowfall. The model needs further development but may hold a potential for clinical use.     

Testing for the presence of 1/f noise in continuation tapping data.

A number of recent papers have suggested that the series of time intervals produced in continuation tapping may have fractal properties. This proposition, nevertheless, was only based on the visual appraisal of graphical results, and was not statistically supported. In the present study, we applied the ARMA/ARFIMA modeling procedures proposed by Wagenmakers, Farrell, and Ratcliff (2005) to test for the presence of long-range dependencies in continuation tapping data. Our results demonstrate the presence of long-range dependencies in most series and offer strong support for the hypothesis that fluctuations in tapping series are fractal in nature.     

Radical Innovation and End-User Involvement: The Ambilight Case

To make technology research more effective and to deal with fierce cost competition, technology research should be more focused on radical innovation and needs to adopt a more end-user-focused approach. Product improvement is already quite often building on knowledge collected around consumers’ experiences with these products to come with a next, improved generation of products. However, in case of creating novel products from “scratch,” this will be more difficult. The user-centered research approach including insights, scenarios, and experience prototypes provides a good method to incorporate the consumer perspective in the earliest stages of the product creation process. The development of the Ambilight TV will be used as a case to illustrate this approach.     

Clinical Characterization and Risk Profile of Individuals Seeking Genetic Counseling for Hereditary Breast Cancer in Brazil

Hereditary breast cancer (HBC) accounts for 5–10% of breast cancer cases and it significantly increases the lifetime risk of cancer. Our objective was to evaluate the sociodemographic variables, family history of cancer, breast cancer (BC) screening practices and the risk profile of cancer affected or asymptomatic at-risk women that undergo genetic counseling for hereditary breast cancer in public Brazilian cancer genetics services. Estimated lifetime risk of BC was calculated for asymptomatic women using the Gail and Claus models. The majority of women showed a moderate lifetime risk of developing BC, with an average risk of 19.7% and 19.9% by the Gail and Claus models, respectively. The average prior probability of carrying a BRCA1/2 gene mutation was 16.7% and overall only 32% fulfilled criteria for a hereditary breast cancer syndrome as assessed by family history. We conclude that a significant number of individuals at high-risk for HBC syndromes may not have access to the benefits of cancer genetic counseling in these centers. Contributing factors may include insufficient training of healthcare professionals, disinformation of cancer patients; difficult access to genetic testing and/or resistance in seeking such services. The identification and understanding of these barriers is essential to develop specific strategies to effectively achieve cancer risk reduction in this and other countries were clinical cancer genetics is not yet fully established.     

Defining task-set reconfiguration: The case of reference point switching

Some researchers argue that task switching involves task-set reconfiguration-that is, changing the existing task set to perform a different task. Although this idea is intriguing, it is often unclear what is reconfigured and which processes are involved in reconfiguration. We addressed these issues by defining task sets, identifying differences between them, and obtaining evidence that was diagnostic of reconfiguration. In two experiments, subjects performed relative judgment tasks that involved comparing a target with a reference point that repeated or switched across trials. The task was the same on every trial, but the task set was not, because a task-set parameter-the reference point-had to be changed. Target-reference point distance effects that changed with the reference point provided diagnostic evidence that reconfiguration occurred, and this reconfiguration led to switch costs. We discuss how our approach can be generalized to define reconfiguration more clearly in other task-switching situations. nt|mis|This research was supported by Grants BCS 0133202 and BCS 0446806 from the National Science Foundation to G.D.L.     

Long-term consequences of early experience on adult avoidance learning in female rats: role of the dopaminergic system

Following our hypothesis that juvenile emotional and/or cognitive experience should affect learning performance at preweaning age as well as adulthood, the present study in female Wistar rats aimed to examine the impact of (i) avoidance training at preweaning age, (ii) exposure to repeated maternal separation, (iii) the combination of both, and (iv) the blockade of dopaminergic neurotransmission on adult two-way active avoidance learning in rats. We found that preweaning, i.e. three week old, rats were less capable of avoidance learning compared to adults. Our main findings revealed that preweaning avoidance training alone improved avoidance learning in adulthood. Furthermore, maternal separation alone also improved avoidance learning in preweaning and in adult rats, but this effect of maternal separation did not add up to the beneficial effect of preweaning avoidance training on adult learning. In addition, the pharmacological blockade of dopamine receptors during preweaning avoidance training via systemic application of haloperidol impaired preweaning avoidance performance in a dose-dependent manner. Testing the haloperidol-treated preweaning presumed "non-learners" as adults revealed that they still showed improved learning as adults. Taken together, our results strongly support the hypothesis that emotional as well as cognitive experience at preweaning age leaves an enduring "memory trace," which can facilitate learning in adulthood. Our pharmaco-behavioral studies suggest that unlike the adult brain, preweaning learning and memory formation is less dependent on dopaminergic mechanisms, which raises the intriguing question of possible alternative pathways.     

Seven principles of goal activation: a systematic approach to distinguishing goal priming from priming of non-goal constructs.

Countless studies have recently purported to demonstrate effects of goal priming; however, it is difficult to muster unambiguous support for the claims of these studies because of the lack of clear criteria for determining whether goals, as opposed to alternative varieties of mental representations, have indeed been activated. Therefore, the authors offer theoretical guidelines that may help distinguish between semantic, procedural, and goal priming. Seven principles that are hallmarks of self-regulatory processes are proposed: Goal-priming effects (a) involve value, (b) involve postattainment decrements in motivation, (c) involve gradients as a function of distance to the goal, (d) are proportional to the product of expectancy and value, (e) involve inhibition of conflicting goals, (f) involve self-control, and (g) are moderated by equifinality and multifinality. How these principles might help distinguish between automatic activation of goals and priming effects that do not involve goals is discussed.     

Using the Internet to find offline sex partners.

We aimed to expand upon the demographic characteristics and gender differences among those who have met someone on the Internet who they later met offline and had sex with as well as any relationship with cybersex, sexually transmitted infections, and online sexual problems. We analyzed data collected through an online questionnaire in 2002 in Sweden including a total population of 1836 respondents of which 1458 used the Internet for sexual purposes. Of those, 35% men and 40% women reported to have met offline sex partners online. The majority reported an occurrence of one to two times, whereas 10% reported six or more times. The analysis suggested women aged 34-49 and 50-65 years, homo- and bisexual men, and singles more likely to have this experience. They were also more likely to have engaged in cybersex. No relationships were found with sexually transmitted infections or online sexual problems. The results suggest that using the Internet to find sex partners may be less hazardous for the general Internet users than pointed out by prior research about this behavior often focusing on specific sub groups of Internet users.     

Perceptual resonance: action-induced modulation of perception

A direct relationship between perception and action implies bi-directionality, and predicts not only effects of perception on action but also effects of action on perception. Modern theories of social cognition have intensively examined the relation from perception to action and propose that mirroring the observed actions of others underlies action understanding. Here, we suggest that this view is incomplete, as it neglects the perspective of the actor. We will review empirical evidence showing the effects of self-generated action on perceptual judgments. We propose that producing action might prime perception in a way that observers are selectively sensitive to related or similar actions of conspecifics. Therefore, perceptual resonance, not motor resonance, might be decisive for grounding sympathy and empathy and, thus, successful social interactions.