Treatment of psychological distress following mastectomy: an initial report

A behavioural programme to treat psychological distress following mastectomy for breast cancer is described. The first 10 patients to be treated were randomly allocated to two treatment groups: Behavioural Programme Only or Behavioural Programme + Drugs (antidepressant medication). Both groups showed improvement over treatment, but the Behavioural Programme + Drugs group appeared to maintain their improvement better.     

Effects of intrahemispheric interference on reaction times to lateral stimuli

Earlier work (Green, 1977) indicated that response by a given hand was slower when stimuli occurred in the visual half field ipsilateral to the body side of hand origin. It was hypothesized that this was due to interference between processing demands originating within the same hemisphere. The present experiments provide evidence regarding the relationship between such interference and the magnitude and type of processing demands. The eight experiments indicate that intrahemispheric interference affects a variety of tasks, including letter shape, letter name, or face matching. The results indicate that reduction in response processing demands reduces the interference. Evidence of interference appeared with a more demanding choice response, but not with a simpler go-no-go response. Manipulations hypothesized to reduce initial, perceptual stimulus processing demands did not reduce the magnitude of interference, possibly because the level of more central stimulus processing demands was still sufficient to interfere with response processing. Interference tended to be minimal on right-hand, match trials, which are hypothesized to involve reduced response processing and reduced central stimulus processing demands. Further investigation of the effects of stimulus processing demands is required.     

How normal and retarded individuals monitor and regulate speed and accuracy of responding in serial choice tasks

These experiments investigate whether or not differences in the way that retarded and nonretarded individuals monitor and regulate speed and accuracy of responding contribute to the slower and more variable performance of retarded subjects on choice reaction time (RT) tasks. Rabbitt (1979, 1981) suggested that efficient choice RT performance is mediated by subjects tracking increasingly faster RT bands on successive trials until, by making and recognizing errors, they discover those very fast RT levels that should be avoided and those safe bands, just above typical error levels, that should be tracked. Experiments 1A and 1B established that most retarded subjects detect their errors as efficiently as nonretarded controls, a finding that excludes the possibility that retarded subjects do not monitor accuracy efficiently but achieve comparable levels of accuracy by consistently responding within very slow RT bands that minimize likelihood of errors. Experiment 2 showed that while a qualitatively similar trial-by-trial tracking mechanism mediates the performance of both groups, retarded subjects are less efficient at constraining RTs within very fast, but safe, bands. Increasing error probabilities at longer RTs suggest that momentary fluctuations in stimulus discriminability and/or attention are factors affecting RT variability in retarded subjects. The RT patterns for various sequences of correct responses initiated and terminated by errors suggest that the effective past experience (EPEX) guiding trial-by-trial RT adjustments of retarded subjects is short and inadequate, and it was argued that this can account for much of the remaining RT variability contributing to retarded-nonretarded differences. Not only does a short EPEX increase variability by giving rise to long error-free sequences of slower than average RT but also, when combined with occasional specified random fluctuations, it suggests why retarded subjects can achieve, but not sustain, RT levels maintained by nonretarded subjects.     

Evidence for the involvement of brain GABA and serotonin systems in the anticonflict effects of chlordiazepoxide in rats

Using male hooded Lister rats the effects of GABAergic and serotonergic treatments alone and with chlordiazepoxide (CDP) were compared with the behavioral effects of CDP in a conditioned conflict procedure with three components; Reward, Time Out, and Conflict. CDP (2.5, 5.0, and 10.0 mg/kg ip) dose- relatedly increased punished and time out responding, but increased rewarded responding in an inversely dose-related manner. Punished responding was enhanced by chronic treatment to a rate which remained stable between 9 and 19 injections. The GABA transaminase inhibitor ethanolamine-O-sulfate (EOS), given chronically in drinking water (5.0 mg/ml), increased punished responding linearly to a high stable level after 2-3 weeks. Rewarded and time out responding were less substantially increased. CDP given with EOS dose- relatedly increased time out and punished responding substantially above the rates found with either treatment alone. The GABA antagonist picrotoxin blocked the increase in punished and time out responding found with EOS and CDP alone. The tryptophan hydroxylase inhibitor p-chlorophenylalanine (PCPA; 100 mg/kg x 3) linearly increased punished responding for the first week of treatment. CDP with PCPA selectively and significantly increased punished responding above the rates for either treatment alone, but the increases were not as substantial as those with EOS + CDP. The serotonin reuptake inhibitor Wy 25093 reduced increases in time out and punished responding under CDP, and the precursor 5-hydroxytryptophan (5-HTP) counteracted increases in punished responding under PCPA but also substantially reduced rewarded responding. These results provide evidence that both increased GABA and decreased serotonin transmission are involved in the anticonflict effects of CDP, as EOS and PCPA both mimicked and potentiated effects of CDP, while picrotoxin, Wy 25093, and 5-HTP counteracted them.(ABSTRACT TRUNCATED AT 250 WORDS)     

Stimulus selection in passive avoidance learning and retention: weanling, periadolescent, and young adult rats

Periadolescent rats exhibit a number of behavioral differences in comparison with younger or older animals. For instance, periadolescents tend to show enhanced acquisition of simple active avoidance tasks, but impaired acquisition of more complex appetitive and aversive discriminations. In this experiment, rats were trained on a simple passive avoidance task at one of three ages, as weanlings (25 days), periadolescents (35 days), or young adults (45 days). Training occurred in the presence of both a redundant discriminative stimulus and a specified, redundant contextual stimulus. The periadolescents did not differ from either younger or older rats in rate of learning the passive avoidance task. The retention performance of these animals was then tested following a change in either, neither, or both of the redundant cues. When a measure of performance that controls for baseline activity was used, it was observed that periadolescents were not disrupted by a change in the redundant discriminative stimulus, a cue change that clearly disrupted performance in 25- and 45-day-old animals, and tended to be more disrupted by the contextual change than younger or older rats. It is hypothesized that the alterations in performance exhibited by periadolescents may be related to an ontogenetic alteration in stimulus selection modulated by the catecholaminergic systems.     

The behavioural treatment of school refusal—A comparative study

A consecutive series of 30 school refusers received behavioural treatment (BTA). Their outcome is compared with that of 16 school refusers who were hospitalized and 20 who received psychotherapy and home tuition. The BTA group showed superior outcome compared to the other two groups. The Home-tuition group did very badly. There was no evidence of symptom substitution in the 28 cases treated successfully by behaviour therapy.     

Revision of the self-monitoring scale

Snyder's (1974) Self-Monitoring Scale exhibits a stable factor structure that does not correspond to the five-component theoretical structure he presents. Sets of face-valid items that better approximate the theoretical structure are described. Correlations between these sets of items and measures of other constructs reveal that four of the five components are positively related to social anxiety. Effective social interaction is supposedly the high self-monitor's forte, and social anxiety appears to be incompatible with this. The correlational results therefore question the entire theory and indicate the need for a narrower definition of the construct. Adopting such a definition from Snyder's review article (1979), we present a 13-item Revised Self-Monitoring scale which measures only sensitivity to the expressive behavior of others and ability to modify self-presentation. A 20-item Concern for Appropriateness scale is also described. This scale measures 2 variables that are directly associated with social anxiety--cross-situational variability and attention to social comparison information. Both scales have acceptable internal consistency, and both yield 2 subscale scores as well as a total score. Prospective users of either scale are advised to treat the 3 scores separately.