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排序方式: 共有151条查询结果,搜索用时 15 毫秒
71.
Karen L. Gould William L. Coventry Richard K. Olson Brian Byrne 《Journal of abnormal child psychology》2018,46(2):251-263
Although attention-deficit/hyperactivity disorder (ADHD) is highly heritable, emerging evidence suggests symptoms are associated with interactions between genes and the environment (GxE) during development. This study tested whether heritability of ADHD symptoms is moderated by two environmental factors: socioeconomic status (SES) and chaos (household disorganisation). A population sample of 520 twin pairs (N = 1040, 52.3% female) from 6 to 15 years completed measures of behavior and home environment. Structural equation modelling was then used to test whether environmental factors were associated with a change in the extent to which genes explain variability in ADHD symptoms. Neither chaos nor SES moderated heritability, with consistent contributions from both genes and environment indicated across socioeconomic strata and levels of chaos. This finding contrasts with those of previous research, underlining the need to replicate results in the emerging field of GxE research across different populations and statistical methods. Robust findings may assist in developing targeted interventions for genetically vulnerable individuals. 相似文献
72.
Temperature concepts and colour are commonly associated (i.e., red is “hot” and blue is “cold”), although their direction of influence (unidirectional, bidirectional) is unknown. Semantic Stroop effects, whereby words like fire influence colour categorization, suggest automatic semantic processing influences colour processing. The experiential framework of language comprehension indicates abstract concepts like temperature words simulate concrete experiences in their representation, where expressions like “red-hot” suggest colour processing influences conceptual processing. Participants categorized both colour (Experiment 1: red, blue; Experiment 2: red, green, blue) and word-meaning with matched lists of hot and cold meaning words in each colour. In Experiments 1 and 2, semantic categorization showed congruency effects across hot and cold words, while colour categorization showed facilitation only with hot words in Experiment 2. This asymmetry reflects a more consistent influence of colour categorization on semantic categorization than the reverse, suggesting experiential grounding effects may be more robust than the effects of semantic processing on colour processing. 相似文献
73.
Recent research has suggested an important role for spatial attention in reading, however the nature of this influence is unclear. Further, it has been shown that intention to engage in linguistic processing can enhance lexical processing. Therefore, we developed a novel paradigm to examine the impact of spatial attention on primed and unprimed lexical processing. In a lexical decision task, targets were preceded by a cue to lexical access and spatial location simultaneously. Results indicated that on spatially valid trials, the lexical cuing effect was large and word processing was enhanced, suggesting that spatial attention influences lexical access. On spatially invalid trials, lexical cuing effects were significantly decreased, resulting in a spatial cuing by lexical cuing interaction. Results from this experiment provide evidence that spatial attention interacts with lexical access during word processing. This novel paradigm provides a new avenue for exploring the relations between spatial attention and reading processes. 相似文献
74.
Gould MS Kalafat J Harrismunfakh JL Kleinman M 《Suicide & life-threatening behavior》2007,37(3):338-352
In this study we evaluated the effectiveness of telephone crisis services/hotlines, examining proximal outcomes as measured by changes in callers' suicide state from the beginning to the end of their calls to eight centers in the U.S. and again within 3 weeks of their calls. Between March 2003 and July 2004, 1,085 suicide callers were assessed during their calls and 380 (35.0%) participated in the follow-up assessment. Several key findings emerged. Seriously suicidal individuals reached out to telephone crisis services. Significant decreases in suicidality were found during the course of the telephone session, with continuing decreases in hopelessness and psychological pain in the following weeks. A caller's intent to die at the end of the call was the most potent predictor of subsequent suicidality. The need to heighten outreach strategies and improve referrals is highlighted. 相似文献
75.
Latent inhibition is a phenomenon by which pre-exposure to a conditioned-stimulus (CS), prior to subsequent pairings of that same CS with an unconditioned-stimulus (US), results in decreased conditioned responding to the CS. Previous work in our laboratory has suggested that the entorhinal cortex is critically involved in the establishment of latent inhibition of cued fear conditioning. Furthermore, utilizing systemic pharmacology, we have demonstrated a role for of NMDA receptors, protein kinase A (PKA), and mitogen activated protein kinase (MAPK, also known as ERK) in latent inhibition of cued fear conditioning, but until now, where these cell signaling cascades are critically activated during latent inhibition of cued fear was unknown. Here, we use direct drug infusion to demonstrate that cell signaling via NMDA receptors, the cAMP/PKA pathway, and the MAPK pathway within the entorhinal cortex are critically involved in latent inhibition of cued fear conditioning. In the present study, CS pre-exposed mice received 20 CS pre-exposures 24h prior to two pairings of the same CS with a 0.53 mA foot shock US, while control animals receive no pre-exposure to the CS. The NMDA antagonist APV (0.25 or 2.5 microg/side), the cAMP inhibitor Rp-cAMP (1.8 or 18.0 microg/side), or the MAPK inhibitor U0126 (0.1 or 1.0 microg/side) were directly infused into the entorhinal cortex prior to pre-exposure. All three drugs produced dose-dependent disruptions in latent inhibition of cued fear conditioning. Importantly, none of the drugs had any effect on cued fear conditioning when administered on training day, suggesting that the effects of each of the drugs were specific to CS pre-exposure. These results are discussed in relation to the potential mechanisms of plasticity that support latent inhibition of cued fear conditioning. 相似文献
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79.
Kerry A. Reynolds Vicki S. Helgeson Howard Seltman Denise Janicki Elizabeth Page‐Gould Margaret Wardle 《Journal of applied social psychology》2006,36(7):1595-1616
The current study examined the impact of interpersonal conflict on mood and physical symptoms for individuals who scored high on a personality characteristic called unmitigated communion (UC), as compared to individuals who did not score high in UC. UC is defined as a focus on others to the exclusion of the self. Forty‐one undergraduate students participated in 7 consecutive nightly interviews. Participants described their social interactions, indicated whether the interaction involved interpersonal conflict, and indicated their distress and physical symptoms at the end of the day. Multilevel modeling analysis demonstrated that conflict adversely affected UC and non‐UC individuals similarly on the same day, but had a more negative impact for UC individuals on the following day. 相似文献
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