Intellectual property rights, moral imagination, and access to life-enhancing drugs

Although the idea of intellectual property (IP) rights--proprietary rights to what one invents, writes, paints, composes or creates--is firmly embedded in Western thinking, these rights are now being challenged across the globe in a number of areas. This paper will focus on one of those challenges: government-sanctioned copying of patented drugs without permission or license of the patent owner in the name of national security, in health emergencies, or life-threatening epidemics. After discussing standard rights-based and utilitarian arguments defending intellectual property we will present another model. IP is almost always a result of a long history of of scientific or technological development and numbers of networks of creativity, not the act of a single person or a group of people at one moment in time. Thus thinking about and evaluating IP requires a traditional model of IP. It follows that the owner of those rights has some obligations to share that information or its outcomes. If that conclusion is applied to the distribution of antiretroviral drugs, what pharmaceutical companies are ethically required to do to increase access to these medicines in the developing world will have to be reanalyzed from a more systemic perspective.     

The role of executive functioning in CBT: a pilot study with anxious older adults

Cognitive behavior therapy (CBT) is an effective treatment for late life anxiety and depression. The successful use of CBT is assumed to rely on cognitive skills known as executive functions (EF; e.g., hypothesis generation, allocation of attention, self-monitoring) governed by the prefrontal cortex. Because older adults sometimes have executive deficits as a consequence of normal aging, EF may be a mediator of CBT outcome in older samples. The current pilot study tested the hypothesis that older adults with executive deficits (as measured by neuropsychological tests) would show decreased therapeutic benefit from CBT for generalized anxiety disorder, as compared to a group with intact EF. Results indicated differential response to CBT within the dysfunction group depending on the stability (and possibly, the etiology) of executive deficits from pre- to posttreatment. Those whose EF scores remained low from pre- to posttreatment did not respond to CBT, while those whose scores improved responded quite well, similar to an Intact EF group. Results indicate that some, but not all, older adults with executive dysfunction show decreased benefit from CBT, and are consistent with the assumption that executive skills are important for the successful use of CBT. However, some participants may show improvement on both mood and cognitive skills during treatment, which is discussed further.     

The Relationship between Reaction Time and Psychometric Intelligence in a Rural Guatemalan Adolescent Population

In industrialized countries reaction time has been found to be related to measures of intelligence and cognitive abilities. Little, however, is known about the validity of using such tasks in nonindustrialized countries. The present research investigated the association between reaction time and psychometric intelligence in a rural Guatemalan adolescent population. Results indicated that speed and consistency of processing on reaction time tasks were related to psychometric intelligence. However, the magnitude of these relationships were considerably smaller than those reported in industrialized populations. Reaction time task performance accounted for less than 5% of the variance in psychometric intelligence. Findings suggest that although reaction time tasks are associated with intelligence, the predictive validity of such measures needs to be established before use in nontraditional populations.     

Facilitated communication: rejected in science, accepted in court-a case study and analysis of the use of FC evidence under Frye and Daubert

This article traces the phenomenon of facilitated communication (FC) from its introduction to the United States in 1990 to its use in recent court proceedings. FC is an alleged breakthrough technique that enables nonverbal individuals with developmental disabilities to communicate via a form of assisted typing. Widespread use of FC resulted in miraculous communications and surprising allegations of abuse. The growing importance and notoriety of FC attracted the interest of the scientific community which rejected the technique after numerous controlled studies were undertaken. Despite the rejection of FC by the scientific community, however, some courts have accepted this unproven technique by evading their state's test of scientific admissibility. It is asserted that court decisions admitting FC evidence are pretextural, and it is argued that FC should not be admitted into court proceedings. In addition, this report analyzes the future of FC in those states that have adopted the newer Daubert standard for scientific evidence.     

Effects of question type and experimenter position on bilateral differences in electrodermal activity and conjugate lateral eye movements

28 dextral males participated in a within-subjects experiment which tasted for the effects of question type (verbal versus spatial) and experimenter-position (in front of or behind the subject) on direction of conjugate lateral eye movements (LEMs) and bilateral differences in skin conductance responses (SCRs). Question dependent asymmetries were observed for LEM direction but not for SCR magnitude. Experimenter-position had no significant effect. The results for LEM direction are consistent with the hypothesis linking eye movements to the left or right with activation of the cerebral hemisphere contralateral to the direction of gaze. The results for SCR magnitude, given certain assumptions, can be reconciled with a hemispheric model of contralateral excitatory control of that system.