Construct and concurrent validity of the Cambridge neuropsychological automated tests in Portuguese older adults without neuropsychiatric diagnoses and with Alzheimer’s disease dementia

We aimed to analyze the construct and concurrent validity of the Rapid Visual Information Processing (RVP), Paired Associates Learning (PAL), Reaction Time (RTI), and Spatial Working Memory (SWM) tests from the Cambridge Neuropsychological Test Automated Battery (CANTAB®). Inclusion criteria were checked in a first session. The CANTAB and additional pencil-and-paper tests were administered within 1 week. The participants (aged 69–96 years) were 137 Portuguese adults without neuropsychiatric diagnoses and 37 adults with mild-to-moderate Alzheimer’s disease dementia. Comparisons were made between the CANTAB tests and between these tests and the Rey Complex Figure Test (RCFT), Verbal Fluency (VF) test, and some Wechsler Memory Scale-III and Wechsler Adult Intelligence Scale-III subtests. Most intra-test correlations were stronger than the CANTAB inter-test correlations. The RVP correlated more with VF animals (.44), the PAL with RCFT immediate recall (–.52), the RTI with RVP mean latency (.42), and the SWM with Spatial Span backward (–.39).     

The Trait Anxiety Scale for Children: A validation study for European Portuguese children and adolescents

The State-Trait Anxiety Inventory for Children is a self-report instrument inspired on the State-Trait theory extended by Spielberger that measures a momentary state of anxiety (state) and a stable tendency to experience anxiety (trait). This study presents an exploratory adaptation of the Trait Scale and provides its psychometric properties for European Portuguese children and adolescents. The influence of sex and age were also explored. Our sample, composed of 402 participants aged 8–14 years, revealed a mean anxiety value of 28.37 (SD = 5.99). As expected, females revealed higher levels of anxiety than boys. Higher anxiety was obtained in our youngest group as compared to the oldest group. The exploratory factor analysis led to retaining only 16-items that presented acceptable adjustment to a one-factorial solution. Good indexes were obtained in the confirmatory analysis. The results also revealed good internal consistency and good test-retest reliability. Our results provide initial evidence that this scale is adequate to measure trait-anxiety in European Portuguese young people.     

Biotechnologies that empower transgender persons to self-actualize as individuals,partners, spouses,and parents are defining new ways to conceive a child: psychological considerations and ethical issues

Today, thanks to biomedical technologies advances, some persons with fertility issues can conceive. Transgender persons benefit also from these advances and can not only actualize their self-identified sexual identities but also experience parenthood. Based on clinical multidisciplinary seminars that gathered child psychiatrists and psychoanalysts interested in the fields of assisted reproduction technology (ART) and gender dysphoria, philosophers interested in bioethics, biologists interested in ART, and endocrinologists interested in pubertal suppression, we explore how new biotechnical advances, whether in gender transition or procreation, could create new ways to conceive a child possible. After reviewing the various medical/surgical techniques for physical gender transition and the current ART options, we discuss how these new ways for persons to self-actualize and to experience parenthood can not only improve the condition of transgender persons (and the human condition as a whole through greater equity) but also introduce some elements of change in the habitual patterns of thinking especially in France. Finally, we discuss the ethical issues that accompany the arrival of these children and provide creative solutions to help society handle, accept, and support the advances made in this area.     

Determinants of Quality of Life in Pre-Frail Older Adults According to Phenotypic Criteria: the VERISAUDE Study

Frailty is a dynamic clinical syndrome considered as part of an age-associated continuum of severity, including pre-frailty as an intermediate frailty status with potential reversibility to robustness. The main purpose of this study was to analyse the relationship between the different domains of quality of life, functional dependence and depressive symptomatology in older adults diagnosed as pre-frail, before progression to frailty occurs. Logistic regression analyses were conducted to examine whether sex, age, level of education and scores in the Geriatric Depression Scale 15-item Short Form (GDS-SF) and the Instrumental Activities of Daily Living Lawton scale determine the worst score in the WHOQOL-BREF (World Health Organization Quality of Life) in older adults meeting one or two frailty phenotypic criteria. Depressive symptomatology (GDS-SF score) was the main determinant of poor quality of life in both groups, and in all areas of WHOQOL-BREF. Age was only associated with poor satisfaction with own health. Female sex and low educational level were linked to low physical QOL and poor self-rated health, respectively, but only in older adults meeting one frailty criterion. Association between functional status and WHOQOL-BREF scores was only found in the univariate analysis. These results underline the importance of identifying multiple aspects, but mainly the presence of depressive symptomatology, as risk factors for all dimensions of quality of life in the pre-frailty process, where interventions might be targeted to reduce the progression of pre-frailty and frailty in older adults.     

Decent Work and Work Motivation in Knowledge Workers: the Mediating Role of Psychological Capital

This article aimed to investigate the role of Decent Work as a predictor of different types of Work Motivation and to explore the possible role of Psychological Capital in mediating this relationship. The Decent Work Questionnaire, the Multidimensional Work Motivation Scale, and the Psychological Capital Questionnaire were administered to 3004 knowledge workers, in Portugal and Brazil. Results from Structural Equation Modeling analyses support the hypothesized model, showing the predictor role of Decent Work and complete and partial mediation effects of PsyCap in different relationships between DW and Work motivation variables. The results also support the idea that a decent work context predicts more autonomous work motivations again with the mediation of PsyCap. In sum, the results suggest that decent work plays an important role in promoting a positive approach to work, and that Psychological Capital is an important mediating variable in the promotion of autonomous Work motivation. Limitations and practical implications conclude the article.     

Domain-specific conflict adaptation without feature repetitions

An influential account of how cognitive control deals with conflicting sources of information holds that conflict is monitored by a module that automatically recruits attention to resolve the conflict. This leads to reduced effects of conflict on the subsequent trial, a phenomenon termed conflict adaptation. A prominent question is whether control processes are domain specific—that is, recruited only by the particular type of conflict they resolve. Previous studies that have examined this question used two-choice tasks in which feature repetition effects could be responsible for domain-specific adaptation effects. We report two experiments using four-choice (Experiment 1) and five-choice (Experiment 2) tasks that contain two types of irrelevant sources of potentially conflicting information: stimulus location (Simon conflict) and distractors (flanker conflict). In both experiments, we found within-type conflict adaptation for both types of conflict after eliminating trials on which stimulus features were repeated from one trial to the next. Across-type conflict adaptation, however, was not significant. Thus, conflict adaptation was due to domain-specific recruitment of cognitive control. Our results add converging evidence to the idea that multiple independent control processes are involved in reactive cognitive control, although whether control is always local remains to be determined.     

Hippocampal PKA/CREB pathway is involved in the improvement of memory induced by spermidine in rats

Spermidine (SPD) is an endogenous polyamine that modulates N-methyl-D-aspartate (NMDA) receptor function, and has been reported to facilitate memory formation. In the current study we determined whether or not the PKA/CREB signaling pathway is involved in SPD-induced facilitation of memory of inhibitory avoidance task in adult rats. The post-training administration of the cAMP-dependent protein kinase (PKA) inhibitor, N-[2-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide [H-89, 0.5 ρmol intrahippocampal (ih)] or the antagonist of the NMDA receptor polyamine-binding site (arcaine, 0.02 nmol ih) with SPD (0.2 nmol ih) prevented memory improvement induced by SPD. Intrahippocampal administration of SPD (0.2 nmol) facilitated PKA and cAMP response element-binding protein (CREB) phosphorylation in the hippocampus 180 min, but not 30 min, after administration, and increased translocation of the catalytic subunit of PKA into the nucleus. Arcaine (0.02 nmol) and H-89 (0.5 ρmol) prevented the stimulatory effect of SPD on PKA and CREB phosphorylation. These results suggest that memory enhancement induced by the ih administration of SPD involves the PKA/CREB pathways in rats.     

Latin-American immigrant women and mental health: differences according to their rural or urban origin

Spain is one of the EU countries that receive most immigrants, especially from Latin America. The process of migration implies a high level of stress what may have repercussions for the mental health of immigrants. The purposes of this study were: (a) to determine whether the degree of mental health of immigrant women differs according to their rural or urban origin, (b) to compare the mental health of immigrant women with that of the female normative sample of host population (Spain). A sample of 186 Latin American immigrant women (142 from urban areas and 44 from rural areas) was recruited in Barcelona by means of a consecutive case method. A structured interview and the SCL-90-R were administered. The results indicated that the immigrant women from rural origin reported higher levels of psychological symptomatology than those from urban areas. Immigrants reported higher levels of psychological symptomatology than the native female population and in most of the psychological symptoms exceeded 90% of the native Spanish population. Migration is a powerful stressor which may lead to psychological distress. Being female of rural origin and being in an illegal situation is related with an increase in symptomatology.     

Quality of Life in Old Age: Problematic Issues

Quality of Life (QoL) is a concept widely used in gerontology, as well as in other fields such as anthropology, health sciences, psychology, sociology and political sciences. Historically, although Aristotle is considered as an antecedent, the term QoL emerged in about the sixties in scientific literature. In the field of ageing, it is considered as an outcome of projects, programmes, services or policies and is used for describing populations, contexts and individuals. QoL is considered by most experts as a multidimensional concept involving multiple domains (health, psychological, social and environmental), containing objective and subjective components. Nevertheless, in recent years, QoL has been reduced to the subjective appraisal, to health or to subjective psychological attributes such as well-being, happiness or life satisfaction. Moreover, conceptual confusions can be found between QoL and other concepts related to positive ageing. In this conceptually-driven paper, after reviewing a set of expert and lay conceptualizations of QoL and identifying the diversity of its components, three critical issues will be discussed: its reduction to health or to the subjective appraisal of a set of domains, the confusion of QoL with other subjective or positive concepts and, finally, its methodological reductionism to self-reports as an exclusive procedure for QoL data collection. From these criticisms some conceptual and methodological suggestions are proposed.