The Portuguese version of Addenbrooke’s Cognitive Examination–Revised (ACE-R) in the diagnosis of subcortical vascular dementia and Alzheimer’s disease

The aim of this study was to investigate the accuracy of the Portuguese version of Addenbrooke’s Cognitive Examination–Revised (ACE-R) in detecting and differentiating early stage subcortical vascular dementia (SVD) from early stage Alzheimer’s disease (AD). Ninety-two subjects (18 SVD patients, 36 AD patients, and 38 healthy controls) were assessed using the ACE-R. Between-group’s differences were evaluated using the Quade’s rank analysis of covariance. The diagnostic accuracy and discriminatory ability of the ACE-R were examined via receiver operating characteristic (ROC) analysis. The ACE-R was able to successfully discriminate between patients and healthy subjects. The mean ACE-R total scores differed between SVD and AD patients; there were also significant differences in attention and orientation and in memory measures between the groups. An optimal cut-off of 72/73 was found for the detection of AD (sensitivity: 97%; specificity: 92%) and SVD (sensitivity: 100%; specificity: 92%).     

Jan Patočka’s sacrifice: philosophy as dissent

This article attempts to bring together the life, situation, and philosophical work of the Czech phenomenologist Jan Pato?ka in order to present his conception of philosophy and sacrifice and to understand his action of dissent and his own sacrifice as spokesman for Charter 77 in light of these concepts. Pato?ka philosophized despite being barred from teaching under the German occupation and under the communist regime, even after he was forced to retire and banned from publication. He also refused the official philosophical categories of communism and, what is more, criticized the very manner in which its ideology allowed it to function. Against the destruction of moral and political life by communist and liberal regimes alike, he outlined the necessity of a “life in the idea” that would be responsive to the notion of sacrifice. Such a position of distance from the things of the world which remains anchored among them is meant to respond to dissatisfaction with the world as it is found and is the very movement of human freedom. Taken together, these three aspects of his philosophical practice made him a dissident, a role he took on more completely when, as part of the Charter 77 movement, he publicly opposed the state, in a course of action that led to his death.     

Object and action picture naming in English and Greek

When two orthographically similar words are displayed using rapid serial visual presentation (RSVP), the repeated letters in the second critical word (W2) are not detected, leading to a deficit in reporting this word known as repetition blindness (RB). In Turkish, letters containing diacritic markings (e.g., y, ö) are considered separate letters, yet are visually highly similar to their non-diacritic analogues (s,o). Two experiments used the phenomenon of RB to investigate whether diacritic letters are represented as more similar to their non-diacritic analogues than are two unrelated letters. In Experiment 1, substantially more RB was found for words differing in just a diacritic (i y im-isim) compared to orthographic neighbours (words differing in a visually non-similar letter, such as ilim-isim). In Experiment 2, the amount of RB for identical words (isim-isim) was comparable to words that differed by a single diacritic marking (i y im-isim). We conclude that diacritic letters are mentally represented as variants of their non-diacritic analogue. Letter / word recognition researchers may be interested in pursuing these findings using standard techniques such as backward masking and orthographic priming.     

Film Review

Tell Me Who Is Haunting You and I'll Tell You Who You Are. A Reading of the film Sixth Sense dir. M. Night Shyamalan (1999)     

Organizational social context and psychopathology of youth in residential care: The intervening role of youth–caregiver relationship quality

Drawing on an ecological approach with multiple informants, this study investigated the mediating role of youth–caregiver relationship quality in associations between different features of residential care settings' organizational social context and youth's psychopathology. Participants were 378 youth aged between 12 and 25 years old, and 54 caregivers aged between 24 and 57 years old, from 29 generalist residential youth care settings in Portugal. Given the hierarchical structure of data, analyses were performed using multilevel modeling. Results revealed that organizational social contexts characterized by higher levels of engagement, stress, and centralization, as perceived by the caregivers, were associated with lower levels of youth's externalizing problems (e.g., aggressive behavior and delinquency), reported by the caregivers, via better youth–caregiver relationship quality, perceived by the youth in care. These findings highlight the relevance of creating an organizational social context in residential care settings that supports caregivers in establishing high-quality relationships with the youth in care, thereby promoting their mental health. This study contributes to the clarification of conflicting findings in previous studies of this field, by offering further empirical investigation of these issues.