An Internal Performance Assessment of CancerGene Connect: An Electronic Tool to Streamline,Measure and Improve the Genetic Counseling Process

CancerGene Connect (CGC) is a web-based program that combines the collection of family and medical history, cancer risk assessment, psychosocial assessment, report templates, a result tracking system, and a patient follow up system. The performance of CGC was assessed in several ways: pre-appointment completion data analyzed for demographic and health variables; a time study to assess overall time per case and to compare the data entry by the genetic counselor compared to the patient, and a measured quality assessment of the program via observation and interview of patients. Prior to their appointment, 52.3 % of 2,414 patients completed the online patient questionnaire section of CGC. There were significant differences in completion rates among racial and ethnic groups. County hospital patients were less likely to complete the questionnaire than insured patients (p?p?CGC. CGC reduces genetic counselor time by approximately 14–46 % compared to average time per case using traditional risk assessment and documentation methods previously reported. All surveyed users felt the questionnaire was easy to understand. CGC is an effective tool that streamlines workflow, and provides a standardized data collection tool that can be used to evaluate and improve the genetic counseling process.     

Classifying Married Adults Diagnosed With Alpha-1 Antitrypsin Deficiency Based on Spousal Communication Patterns Using Latent Class Analysis: Insights for Intervention

Married adults are increasingly exposed to test results that indicate an increased genetic risk for adult-onset conditions. For example, a SERPINA1 mutation, associated with alpha-1 antitrypsin deficiency (AATD), predisposes affected individuals to diseases such as chronic obstructive pulmonary disease (COPD) and cancer, which are often detected in adulthood. Married adults are likely to discuss genetic test results with their spouses, and interpersonal research suggests that spouses’ communication patterns differ. Latent class analysis was used to identify subgroups of spousal communication patterns about AATD results from a sample of married adults in the Alpha-1 Research Registry (N?=?130). A five-class model was identified, and the subgroups were consistent with existing spousal-communication typologies. This study also showed that genetic beliefs (e.g., genetic stigma), emotions, and experiences (e.g., insurance difficulties) covaried with membership in particular subgroups. Understanding these differences can serve as the foundation for the creation of effective, targeted communications interventions to address the specific needs and conversational patterns of different kinds of couples.     

Perceived Cognitive Efficiency and Subjective Well-Being in Late Adulthood: The Impact of Developmental Factors

The current literature shows cross-cultural differences related to implicit theories of ageing. Specifically, in the Western individualistic cultural context, elderly people are perceived as obsolete, weak and unable to contribute usefully to society, whereas in collectivistic cultures, older people are venerated as a source of knowledge and cultural traditions (e.g. Yoon et al. in Psychol Aging 15:694–704, 2000). The focus of the current study was to investigate the effect of age-related factors affecting self-referent well-being in the Italian population. One hundred and thirty-nine healthy adults (20–99 years) were recruited in Northern Italian (i.e. individualistic context) and Sardinian (i.e. collectivist context) contexts and were, respectively, assigned to the following groups: Young (20–30 years old), Old (65–74 years old) and Very Old (>75 years old). Participants were administered a battery of tests, including self-referent cognitive efficiency scales, subjective psychological well-being, depression and psychological distress scales. Participants from Sardinia showed greater levels of well-being and lower levels of psychological distress than adults from Northern Italy. Moreover, participants from the Old group reported more coping strategies, emotional competencies and personal satisfaction, as well as fewer depressive symptoms, than the Very Old group. One possible explanation is that sociocultural contexts emphasising the positive social role of the elderly like that prevailing in Sardinia promote psychological well-being in late adulthood.     

The Importance of Formative Assessment in Science and Engineering Ethics Education: Some Evidence and Practical Advice

Recent research in ethics education shows a potentially problematic variation in content, curricular materials, and instruction. While ethics instruction is now widespread, studies have identified significant variation in both the goals and methods of ethics education, leaving researchers to conclude that many approaches may be inappropriately paired with goals that are unachievable. This paper speaks to these concerns by demonstrating the importance of aligning classroom-based assessments to clear ethical learning objectives in order to help students and instructors track their progress toward meeting those objectives. Two studies at two different universities demonstrate the usefulness of classroom-based, formative assessments for improving the quality of students’ case responses in computational modeling and research ethics.     

Book review of Applied Behavior Analysis Advanced Guidebook: A Manual for Professional Practice (2nd edition)

The second edition of Applied Behavior Analysis Advanced Guidebook: A Manual for Professional Practice (Luiselli, 2023) covers 17 chapters on topics that are relevant to applied behavior analysis practitioners. In this review, we discuss the purpose and intended audience of the Guidebook, briefly summarize the contents of the Guidebook, and critically evaluate the contents with respect to breadth and depth, audience fit, organization, and cohesion. In addition, we discuss emerging areas that are highlighted in the Guidebook (i.e., technology and telehealth, diversity and multiculturism, and practice-oriented research).     

The role of personal and key resources in the family‐to‐work enrichment process

Based on the work‐home resources model, the aim of the present research was to test a process model of family‐to‐work enrichment by examining whether self‐efficacy (i.e., personal resource) mediates the relationship between support from one's family and work engagement. Further, it was assumed that positive affectivity (i.e., key resource) moderates the relation between family support and self‐efficacy. Using an occupationally heterogeneous sample of Slovenian employees (n = 738), we found support for a mediating effect of self‐efficacy as well as for the moderating role of positive affectivity. In general, our results broaden the understanding of work‐family enrichment processes and provide support for the work‐home resources model. In addition, they point to the relevant role of personal and key resources in work‐family interactions.     

A General Population Twin Study of Conduct Problems and the Auditory P300 Waveform

Reduced amplitude of the P300 event-related potential has been consistently associated with a variety of externalising problems, including conduct disorder. The few available genetically-informative studies of these relationships, however, were conducted among adolescents/adults (i.e., at an age when conduct disorder has typically already become manifest). Among 200 general population twins with a mean age of 9 years (range 6–14 years), we studied the relationship between the P300 waveform elicited by an auditory oddball task and the DSM-oriented conduct problems scale of the Child Behavior Checklist 6–18. Conduct problems scores were negatively and significantly correlated (r?=??0.19, p?=?0.01) with P300 amplitude; correlations between P300 amplitude and the other DSM-oriented Child Behavior Checklist scales were non-significant, except for oppositional defiant problems (p?=?0.01). We found moderate heritability estimates for both P300 amplitude (0.58, CI:0.37;0.73) and conduct problems (0.52, CI:0.25;0.70). Bivariate twin analyses indicated that the covariation between these two phenotypes can be explained by additive genetic factors only, with a genetic correlation of ?0.33. An association between reduced P300 amplitude and conduct problems can be substantiated already in childhood, at an age that precedes the most typical onset of conduct disorder. This relationship appears to be genetic in nature. Reduced P300 amplitude can represent a valuable marker for conduct problems, and can contribute to the early identification of children at high-risk for conduct disorder.     

Frustrated,but not flustered: The benefits of hierarchical approach motivation to weathering daily frustrations

Variations in the organization of personal goals are thought to be important to self-regulation, yet relevant measures and evidence is largely lacking. In two studies (total N = 217), participants were prompted to self-generate personal goals at three levels of a goal hierarchy (low, mid, and high), following which they rated all of these goals along an approach-avoidance dimension. A hierarchical approach measure was created from these ratings and this novel individual difference measure was hypothesized to predict the better self-regulation of goal frustrations in daily life. Such predictions were confirmed. For example, daily frustrations precipitated anger among those low but not high, in hierarchical approach (Study 2). The findings are important theoretically as well as from a measurement perspective.     

Residential mobility and the family context: A developmental approach

The goal of this study was to examine the links between residential mobility and the family context, whether these links varied across developmental periods (early childhood, middle childhood, or adolescence), and how they were associated with children's achievement and behavioral outcomes. Longitudinal data from a diverse sample of over 1000 U.S. children were used to explore family structure (marital and employment change), process (quality of the home and maternal sensitivity and depression), and residential mobility. Results of structural equation models indicated that associations between residential mobility and family structure and process varied across developmental periods, with significant links found for family process in early childhood and structure in middle childhood and adolescence. We found evidence of indirect associations between residential mobility and children's outcomes through family process in early childhood and of a direct association with internalizing behaviors in adolescence. We provide implications for programs and policies for residentially mobile children.     

Concordance Between Measures of Anxiety and Physiological Arousal Following Treatment of Panic Disorder in Adolescence

This study examined the concordance (or synchrony/desynchrony) between adolescents' self-reports of anxiety and physiological measures of arousal (heart rate) both prior to and after treatment for panic disorder. Results indicated a decline in reported subjective units of distress (SUDS) for the treatment group only at the post-treatment measurement for two of three tasks. Within the treatment group, heart rate changes during the Behavioral Approach Test (BAT) were observed following treatment for one task only. Implications of this apparent desynchrony between self-report and physiological measures in adolescent panic disorder are discussed, with cognitive changes in participants' perception of anxiety after treatment suggested as an important factor in recovery.